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In experimental studies, enkephalins (ENKs) and related opioids have been implicated as negative regulators of breast cancer development by enhancing immune-mediated tumoral defense as well as directly inhibiting cancer cells. We hypothesized that plasma levels of ENKs are predictive of the long-term breast cancer risk. Therefore, our objective was to measure pro-ENK A, a surrogate for mature ENK,
Popular Abstract in Swedish Människans utveckling och fysiologiska anpassning till upprätt kroppställning är beroende av en rad blodtrycksreglerande mekanismer. Vid ortostatisk hypotension sjunker blodtrycket i samband med uppresning från liggande till stående. Detta beror på en sviktande cirkulationsanpassning så att organismen inte förmår att upprätthålla ett tillräckligt högt blodtryck. SymtomeOrthostatic hypotension (OH) is believed to be an important cause of cerebral hypoperfusion, leading to chronic fatigue, blurred vision, unsteadiness, dizziness and sometimes syncope. It may also result in episodes of confusion, falls and fractures. The coupling between OH and organic dementia is not clear. Our findings in a large group of patients with Alzheimer's disease, vascular- and frontotem
SI-MENTORSKAP SI-programmet vid KEG På KEG erbjuds SI-programmet på följande kurser/program till våren 2016: Humanekologi: Miljö, kultur och utveckling, grundkurs Kandidatprogrammet i utvecklingsstudier (BIDS) Vill du bli SI-mentor till hösten 2016 och studerar/har studerat samhällsgeografi, humanekologi eller utvecklingsstudier? Kontakta elin.brudin@keg.lu.se för mer information. Mentorn ska
https://www.keg.lu.se/sites/keg.lu.se/files/mentorskapsprogrammet.pdf - 2026-05-11
Ansökan om tillgodoräknande av hel kurs eller del av kurs Ange nedan vilken kurs som du önskar ersätta. Gäller det del av kurs, ange momentet/provkoden. Gäller det termin 5 i kandidatprogrammen, skriv Valbar kurs. Kurskod Kursens namn Antal hp Ange nedan den eller de kurser du vill åberopa (som du har läst tidigare). Gäller det del av kurs, ange momentet/provkoden. Kurskod Kursens namn Lärosäte An
https://www.isk.lu.se/sites/isk.lu.se/files/tillgodoraknande_blankett_10.pdf - 2026-05-11
Styrelseprotokoll 2019-02-13 Sida 1 av 3 STYRELSEPROTOKOLL Diarienummer Biologiska institutionen Datum 2019-02-13 Protokoll institutionsstyrelsen Närvaro Närvarande ledamöter Carin Jarl Sunesson, prefekt, ordförande, Marita Cohn, Violeta Kaleskovska, Carina Rasmussen, Karin Rengefors, Johannes Rousk, Tobias Uller Frånvarande ledamöter Nils Cronberg, Jacob Roved, Marcus Stensmyr, Maja Tarka, Niklas
https://www.biologi.lu.se/internt/sites/biologi.lu.se.internt/files/2020-12/styrelseprotokoll20190213.pdf - 2026-05-11
Plasma metabolomics holds potential for precision medicine, but limited information is available to compare the performance of such methods across multiple cohorts. We compared plasma metabolite profiles after an overnight fast in 11,309 participants of five population-based Swedish cohorts (50–80 years, 52% women). Metabolite profiles were uniformly generated at a core laboratory (Metabolon Inc.)
While organisms have evolved to cope with predictable changes in the environment, the rapid rate of current global change presents numerous novel and unpredictable stressors to which organisms have had less time to adapt. To persist in the urban environment, organisms must modify their physiology, morphology and behaviour accordingly. Metabolomics offers great potential for characterising organism
Oral assessment is an important method to evaluate the learning outcomes of scientific courses. However,there are certain limitations when oral assessment is applied.One of these limitations, which is not apparent in anonymous written exams, is the existence of biases which could lead to unfair (positive or negative) outcomes of the assessment. This could lead to decreased motivation and sense of
DevOps has significantly improved the software development life-cycle by enabling fast, automated, and continuous integration and deployment (CI/CD). However, its application to Cyber-Physical Systems (CPS) presents unique challenges that require rethinking of traditional practices. DevOps in CPS becomes even more challenging when we consider sustainability, which is becoming increasingly importan
Recessive diseases arise when both copies of a gene are impacted by a damaging genetic variant. When a patient carries two potentially causal variants in a gene, accurate diagnosis requires determining that these variants occur on different copies of the chromosome (that is, are in trans) rather than on the same copy (that is, in cis). However, current approaches for determining phase, beyond pare
Title: Rules, roles and risks- A study on occupational health and safety in the construction sector Author: Tova Westerlund Supervisor: Radhlinah Aulin Examiner: Anne Landin Aim & goal: The purpose of this report has been to investigate occupational health and safety risks in the construction sector, how responsibility roles relate to these risks, and the impact of Arbetsmiljöverkets regulatio
INTRODUCTION: Survival and healthcare for patients with congenital heart disease have improved, and the number of pregnancies among women of childbearing age with congenital heart disease has increased. Our aim was to investigate obstetric outcomes in a large retrospective, national registry study of women with congenital heart disease compared to controls.MATERIAL AND METHODS: The study included
Independence and collaboration both play crucial roles in PhD students’ research practice and in their socialization into the PhD role. This study examines how theexpectation of PhD students' academic independence intersects with the need for more collaborative engagements within research groups. Drawing on interviews with supervisors and an analysis of co-authorship patterns in PhD studentdissert
BACKGROUND: The implementation of COVID-19 vaccination among older persons at nursing homes has lowered the infection-associated mortality considerably, but emerging virus variants and decline in vaccine-induced immunity over time necessitate examination of future booster dosing strategies. The overall aim of this study was to assess vaccine protection against COVID-19 mortality in relation to tim
Recent studies of selective auditory attention have demonstrated that neural responses recorded with electroencephalogram (EEG) can be decoded to classify the attended talker in everyday multitalker cocktail-party environments. This is generally referred to as the auditory attention decoding (AAD) and could lead to a breakthrough for the next-generation of hearing aids (HAs) to have the ability to
Cell death plays a pivotal role in many physiological processes, such as cell homeostasis, embryonic development, immune defence and in the pathophysiology of numerous diseases, such as cancer, infections and degenerative diseases. However, the lack of a comprehensive and up-to-date resource on cell death regulators poses a significant challenge to researchers in the field. Existing databases are of
Background Exposure to hexavalent chromium (Cr(VI)) can occur during occupational activities and leading lung cancer. MicroRNA (miRNA) plays an important part in carcinogenesis. Whether Cr(VI) exposure causes cancer-related miRNA changes is yet uncharacterized. Methods This study included 89 Cr(VI) exposed workers and 47 controls. MiRNAs were extracted from plasma followed by library preparations,
Stem cell transplantation is a cornerstone in the treatment of blood malignancies. The most common method to harvest stem cells for transplantation is by leukapheresis, requiring mobilization of CD34+ hematopoietic stem and progenitor cells (HSPCs) from the bone marrow into the blood. Identifying the genetic factors that control blood CD34+ cell levels could reveal new drug targets for HSPC mobili
