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Psychometric evaluation of the anticipatory grief scale in a sample of family caregivers in the context of palliative care

Introduction: In palliative care, family caregivers are often faced with experiences of grief in anticipation of the loss of a close person. An instrument designed to measure this form of grief is the Anticipatory Grief Scale, which includes 27 items and has been used in several studies in various contexts. However, the instrument has not been validated. Aim: The aim was to evaluate the psychometr

Ventilation with increased apparatus dead space vs positive end-expiratory pressure : Effects on gas exchange and circulation during anesthesia in a randomized clinical study

Atelectasis formation can be reduced by positive endexpiratory pressure (PEEP), but resulting increases in intrathoracic pressure could affect circulation. We have earlier demonstrated that increased tidal volumes with larger apparatus dead space improves oxygenation and sevoflurane uptake. In the present study, we hypothesize that isocapnic ventilation with increased tidal volumes increases oxyge

The success of sequence capture in relation to phylogenetic distance from a reference genome : a case study of avian haemosporidian parasites

Genomic sequencing of avian haemosporidian parasites (Haemosporida) has been challenging due to excessive contamination from host DNA. In this study, we developed a cost-effective protocol to obtain parasite sequences from naturally infected birds, based on targeted sequence capture and next generation sequencing. With the genomic data of Haemoproteus tartakovskyi as a reference, we successfully s

Fermentation of Cauliflower and White Beans with Lactobacillus plantarum – Impact on Levels of Riboflavin, Folate, Vitamin B12, and Amino Acid Composition

As diets change in response to ethical, environmental, and health concerns surrounding meat consumption, fermentation has potential to improve the taste and nutritional qualities of plant-based foods. In this study, cauliflower, white beans, and a 50:50 cauliflower-white bean mixture were fermented using different strains of Lactobacillus plantarum. In all treatments containing cauliflower, the pH

Interkulturell kompetens kan stärka medicinsk forskning

Samarbetet mellan forskare i Östersjöregionen har aldrig varit starkare. Ändå finns stora utmaningar, vilket blir tydligt i en aktuell debatt i Tyskland om digitaliseringar i vården där politiker lyfter fram Sverige som förebild.Samarbetet mellan forskare i Östersjöregionen har aldrig varit starkare. Ändå finns stora utmaningar, vilket blir tydligt i en aktuell debatt i Tyskland om digitaliseringar i vården där politiker lyfter fram Sverige som förebild.

The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death

Background and aims: A vulnerable plaque is an atherosclerotic plaque that is rupture-prone with a higher risk to cause cardiovascular symptoms such as myocardial infarction or stroke. Mimecan or osteoglycin is a small leucine-rich proteoglycan, important for collagen fibrillogenesis, that has been implicated in atherosclerotic disease, yet the role of mimecan in human atherosclerotic disease rema

Stromal progesterone receptor expression and long-term survival in patients with resected periampullary adenocarcinoma

Background: Early trials have reported a beneficial effect from tamoxifen treatment in patients with unresectable pancreatic cancer, in particular in women. However, the presence and prognostic significance of female hormone receptors in pancreatic or other periampullary cancers has not yet been described. Methods: Immunohistochemical screening of normal and malignant pancreatic tissue revealed t

Methylation patterns and chromatin accessibility in neuroendocrine lung cancer

Lung cancer is the worldwide leading cause of death from cancer. Epigenetic modifications such as methylation and changes in chromatin accessibility are major gene regulatory mechanisms involved in tumorigenesis and cellular lineage commitment. We aimed to characterize these processes in the context of neuroendocrine (NE) lung cancer. Illumina 450K DNA methylation data were collected for 1407 lung

Quasi-Newton waveform iteration for partitioned surface-coupled multiphysics applications

We present novel coupling schemes for partitioned multiphysics simulation that combine four important aspects for strongly coupled problems: implicit coupling per time step, fast and robust acceleration of the corresponding iterative coupling, support for multirate time stepping, and higher-order convergence in time. To achieve this, we combine waveform relaxation—a known method to achieve higher-

Att gestalta en region : Källornas strategier och mediernas föreställningar om Öresund

Popular Abstract in Swedish NÄR ÖRESUNDSBRON INVIGDES ÅR 2000 nådde förväntningarna på dansk-svensk integration sin kulmen. Prognoser och framtidsspekulationer haglade. Nyhetsbrev, reklamkampanjer, webbplatser och konferenser producerades på löpande band. Öresundsbron förenade Öresundsregionen. Öresundsregionen förenade skåningar och själlänningar. Tillsammans skulle de forna broderfolken skapa enThe Öresund Bridge between Denmark and Sweden was inaugurated in the year 2000, connecting the city of Malmö and the Danish capital Copenhagen. The bridge was an important move towards the visionary realisation of a transnational Öresund Region. In this dissertation the communicative aspects of the regional process are put in focus. The vision of the Öresund Region that developed during the 1990s

Food sources of fat and sex hormone receptor status of invasive breast tumors in women of the malmö diet and cancer cohort.

We examined associations between food intakes and incident breast cancer, defined by estrogen receptor (ER) and progesterone receptor (PR) status in the Malmö Diet and Cancer cohort (17,000 women aged 45-73 yr). The hazard ratios (HRs) of ER+PR+ (n = 270), ER+PR- (n = 87), and ER-PR- (n = 61) tumors and all cancer (n = 544) were estimated after 10 yr of follow-up. In multivariate analysis of ER+PR

The Assassination of Mohsen Fakhrizadeh: What Are the Iranian Regime’s Options?

This past Friday, the architect of the Iranian nuclear program, Mohsen Fakhrizadeh, was assassinated in a well-organized raid 70 km outside the city of Tehran. A commander of the Islamic Revolutionary Guard Corps (IRGC), Fakhrizadeh headed the important Organization of Defensive Innovation and Research of the Ministry of Defense, which conducted nuclear weapons research. His killing reflects a maj

The Al-Masri Assassination: Another Iranian Intelligence Failure

On August 7, 2020, the number 2 figure in al-Qaeda, Abdullah Ahmad Abdullah (known as Abu Muhammad al-Masri), was gunned down in Tehran. Al-Masri’s very presence in Iran exhibited the close relationship Tehran has with the Sunni terrorist organization, and his slaying shows the weakness of Iranian counterintelligence. The regime’s frustration at this intelligence failure will likely be expressed t

Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration

The transcription factor hepatic leukemia factor (HLF) is strongly expressed in hematopoietic stem cells (HSCs) and is thought to influence both HSC self-renewal and leukemogenesis. However, the physiological role of HLF in hematopoiesis and HSC function is unclear. Here, we report that mice lacking Hlf are viable with essentially normal hematopoietic parameters, including an intact HSC pool durin

Current opportunities for clinical monitoring of axonal pathology in traumatic brain injury

Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces transmitted to the brain during impact. Axonal injury leads to brain network dysfunction, significantly contributing to cognitive and functional impairments frequently observed in TBI survivors. Diffuse axonal injury