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BACKGROUND AND PURPOSE: Genome-wide association (GWA) studies have identified a few risk loci for ischaemic stroke, but these variants explain only a small part of the genetic contribution to the disease. Coding variants associated with amino acid substitutions or premature termination of protein synthesis could have a large effect on disease risk. We performed an exome array analysis for ischaemi
The risk of solid and hematological malignancy in patients with Turner syndrome, characterized by X chromosome monosomy in women, and Klinefelter syndrome, characterized with two and more X chromosomes in men, is not well established, but such evidence may have etiological implications on cancer development. We identified a total of 1,409 women with Turner syndrome and 1,085 men with Klinefelter s
Stem cell therapies for neurological disorders are rapidly moving towards use in clinical trials. Before initiation of clinical trials, extensive pre-clinical validation in appropriate animal models is essential. However, grafts of human cells into the rodent brain are rejected within weeks after transplantation and the standard methods of immune-suppression for the purpose of studying human xenog
Background: Previous studies regarding the association between serum 25-hydroxyvitamin D (25OHD3) and breast cancer risk have not been conclusive. The aim of this study was to investigate the potential association between pre-diagnostic serum 25OHD3 levels and the risk of different subtypes of breast cancer. Materials and methods: The study was based on The Malmö Diet and Cancer Study recruiting 1
Low serum apolipoprotein (Apo) A1 concentrations and high serum ApoB concentrations may be better markers of the risk of cardiovascular disease than high-density lipoprotein (HDL) and low-density lipoprotein (LDL). However, the associations between modifiable lifestyle factors and Apo concentrations have not been investigated in detail. Therefore, this study investigated the associations between A
Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. Most of the approaches currently under development involve transplantation of immature progenitors that subsequently undergo phenotypic and functional maturation in vivo, and predicting the long-term graft outcome already at the progenitor stage remains a challenge. Here, we took an unbiased approach to
Endogenous retroviruses (ERVs), which make up 8% of the human genome, have been proposed to participate in the control of gene regulatory networks. In this study, we find a region- and developmental stage-specific expression pattern of ERVs in the developing human brain, which is linked to a transcriptional network based on ERVs. We demonstrate that almost 10,000, primarily primate-specific, ERVs
OBJECTIVES: Post-stroke cognitive impairment (PSCI) has considerable impact on patients and society. However, long-term studies on PSCI are scarce and may be influenced by assessment methods and selection bias. We aimed to (i) assess the prevalence of long-term PSCI; (ii) compare two common cognitive assessment instruments; and (iii) compare cognitive function of long-term stroke survivors with no
In general, melanoma can be considered as a UV-driven disease with an aggressive metastatic course and high mutational load, with only few tumors (acral, mucosal, and uveal melanomas) not induced by sunlight and possessing a lower mutational load. The most commonly activated pathway in melanoma is the mitogen-activated protein kinase (MAPK) pathway. However, the prognostic significance of mutation
Increased risks of certain cancers have been observed in patients with hepatitis C virus (HCV) infection. However, data on other cancer sites/types are lacking. We analyzed systematically the risk of developing 35 common cancers in patients with HCV infection using a nationwide Swedish database. Patients with HCV infection were identified from the Swedish Hospital Inpatient and Outpatient Register
Systemic lupus erythematosus (SLE) is a severe chronic inflammatory autoimmune connective tissue disease. Despite major efforts, SLE remains a poorly understood disease with unpredictable course, unknown etiology and complex pathogenesis. Apoptosis combined with deficiency in clearing apoptotic cells is an important etiopathogenic event in SLE, which could contribute to the increased load of poten
The study of airborne bacteria relies on a sampling strategy that preserves their integrity and in situ physiological state, e.g. viability, cultivability, metabolic activity, and ice-nucleation activity. Because ambient air harbors low concentrations of bacteria, an effective bioaerosol sampler should have a high sampling efficiency and a high airflow. We characterize a high-flow-rate impinger wi
Summary Sheet and Statement of Purpose – Master's programme in Wireless Communications Admissions for 2023 1/6 Summary Sheet and Statement of Purpose – Master’s programme in Wireless Communications Admissions for 2023 Questions? Please check out FAQ on: www.lth.se/english/faq Here you can also find guidelines on how to convert local credits into ECTS. Personal information (same as your universitya
https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2022-10/Summary%20Sheet%20Wireless.pdf - 2026-05-08
Summary Sheet and Statement of Purpose – Master's programme in Wireless Communications 1/6 Summary Sheet and Statement of Purpose – Master’s programme in Wireless Communications Questions? Please check out FAQ on: www.lth.se/english/faq Here you can also find guidelines on how to convert local credits into ECTS. Personal information (same as your universityadmissions.se account) First name Last na
https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2024-10/Summary-sheet-wireless.pdf - 2026-05-08
The decline in areal BMD (aBMD) in men may start as early as age 19, but it is debated whether proximal femoral strength follows the same pattern. We measured FN aBMD in a cross-sectional cohort of 1101 men aged 18-28 yr with two-dimensional DXA. Body height, weight, jump height, grip strength, and maximum knee extension torque muscle strength were measured with standard tests, after which BMI was
Purpose: To achieve the high sensitivity of digital breast tomosynthesis (DBT), a time-consuming reading is necessary. However, synthetic mammography (SM) images, equivalent to digital mammography (DM), can be generated from DBT images. SM is faster to read and might be sufficient in many cases. We investigate using artificial intelligence (AI) to stratify examinations into reading of either SM or
OBJECTIVES: To describe the prevalence of cardiovascular disease (CVD) at the time of diagnosis of adult-onset type 1 (T1D) and type 2 (T2D) diabetes, in a recent cohort and compare to a previous cohort from the same region. Further, to explore factors influencing the prevalence of pre-existing CVD, including age, sex, body mass index (BMI) and C-peptide; in the later cohort also heart failure, hy
Direct electrochemical measurements of glutamate release in vivo were combined with optogenetics in order to examine light-induced control of glutamate neurotransmission in the rodent brain. Self-referenced recordings of glutamate using ceramic-based microelectrode arrays (MEAs) in hippocampus and frontal cortex demonstrated precise optical control of light-induced glutamate release through channe
The following article investigates Keats’s expansion of the notion of Eros, arguing that it forms a dialectic relation between the self-sufficiency of the lover and a dream of mutual exchange between the subject and its object of desire. In order to discern the specific concerns of Keats in this regard, the study analyzes a letter sent to his friend John Hamilton Reynolds on the 19th of February 1The following article investigates Keats's expansion of the notion of Eros, arguing that it forms a dialectic relation between the self-sufficiency of the lover and a dream of mutual exchange between the subject and its object of desire. In order to discern the specific concerns of Keats in this regard, the study analyzes a letter sent to his friend John Hamilton Reynolds on the 19th of February 1
Introduction: Oesophageal resection carries significant morbidity and mortality. Artificial intelligence (AI) advances in medical research enable enhanced predictions, flexibility, and interpretability, especially for complex interactions and nonlinear relationships. Material and methods: We used a register-based case-control design nested within prospectively collected data from the Swedish Natio
