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Cryo-optical setup for wide-field microscopy and spectroscopy of luminescent nanomaterials
Studying photoluminescence (PL) is essential for understanding and engineering light-emitting nanomaterials. Heterogeneous samples, such as thin films and microstructures, require characterization of the spatial distribution of PL intensity, spectra, lifetimes, and photon correlations at the microscale under variable temperatures. Here we describe a cryo-optical setup for micro-PL imaging, spec
Editorial for Themed Issue “Functional Nanostructures: Materials to Applications”
Editorial for the special issue of "Small Structures"
ACS Nano Journal Cover
Depiction of sinusoidal displacement in nanocrystal superlattices through a minimum of geometric shapes and contrasting colors. This cover pays homage to the Bauhaus movement, celebrating human-made craftsmanship, clarity, and accessibility in scientific design, and remains faithful to its fundamental principle: less is more.
Journal of Chemical Physics Front Cover
2023 JCP Emerging Investigators Special Collection: Tuning perovskite nanocrystal superlattices for superradiance in the presence of disorder
“Oxygen tone” drives stage-specific OPC phenotypes for cell-based stroke therapy
Oligodendrocyte precursor cells (OPCs) display functional plasticity beyond myelination. Kuwata et al. explore how hypoxia shapes OPC features after ischemic stroke. Combining single-cell transcriptomics with in vivo and ex vivo models, they reveal oxygen-dependent OPC phenotypes promoting angiogenesis and remyelination, highlighting OPC versatility and potential for novel stroke cell therapies.
Aducanumab binding to Aβ1-42 fibrils alters dynamics of the N-terminal tail while preserving the fibril core
Aducanumab, a human IgG1 antibody with plaque-clearing effects and modest clinical benefit, binds selectively to aggregated Aβ via the N-terminal region. Yet, the molecular details of how the antibody engages Aβ1-42 fibrils remain unresolved. Using magic-angle spinning NMR, we show that binding of aducanumab preserves the overall architecture of the Aβ1-42 fibril core while inducing significant st
Long-term exposure to black carbon and incident asthma and chronic obstructive pulmonary disease in adults : The Danish Nurse Cohort
Background: Air pollution is a known risk factor for chronic respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). However, evidence regarding the role of black carbon (BC) remains mixed and sparse. This study aimed to examine the association of long-term exposure to air pollution, focusing on BC, with incident asthma and COPD in adults. Method: We followed 28,73
SERUM MEDIATED PHAGOCYTOSIS OF NECROTIC MATERIAL BY POLYMORPHONUCLEAR LEUKOCYTES IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE).
Serum Mediated Phagocytosis Of Necrotic Material By Polymorphonuclear Leukocytes May Be Used As a Tool To Predict Clinical Manifestations In Systemic Lupus Erythematosus
Highly-destabilized ligand field excited states of iron carbene complexes and their relation to charge transfer state lifetimes
Lifetimes of photoexcited charge transfer (CT) states in transition metal chromophores are influenced by low-lying ligand field (LF) excited states, especially for 3d metal complexes. To manipulate interactions between LF and CT states, it is important to be able to control LF excited state energies using tunable synthetic variables. In this report, we use Fe 2p3d L3-edge resonant inelastic X-ray
Multiexciton absorption cross sections of CdSe@CdS nanorods studied using pump–repump–probe spectroscopy
While the multiexciton dynamics in semiconductor nanocrystals is widely explored, to determine the absorption cross sections for multiexcitons of varying order is still a challenge. In this study, we performed pump–repump–probe transient absorption (ppp-TA) spectroscopic measurements on CdSe@CdS nanorods to gain insights into the absorption cross sections for multiexcitons. By tuning the pump–repu
Urban living labs as cracks, not doors : Reimagining experimentation in transport (and beyond)
Urban Living Labs (ULLs) are widely promoted as experimental spaces for urban innovation, particularly in EU policy contexts. Yet their design is often shaped by current institutional logics, EU-funding structures, and sector-specific constraints, especially in transport, a domain marked by technical path dependencies and dominant narratives of efficiency and optimization. These conditions risk na
Self- and co-assembly of the amyloid suppressing chaperone DNAJB6b
The clustering of certain proteins into oligomers and fibrils, known as amyloids, underlies the pathology of diseases such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. These processes are counteracted by the cellular protein quality control system, which includes molecular chaperones that interact with disease-associated proteins. One such chaperone is DNAJB6b, which has gaine
How Antisolvent-Induced Ligand Stripping Shapes CsPbX3 Nanocrystals and Their Assemblies
Supercrystals of lead-halide perovskite nanocrystals combine the semiconducting properties of bulk perovskites with quantum confinement effects and extend them to the macroscopic scale. Supercrystals assembled via a two-layer phase diffusion process using an acetonitrile antisolvent were recently shown to be unusually robust. We investigate how the acetonitrile-assisted self-assembly process influ
An unusual case of Streptococcus pyogenes infective endocarditis demonstrating the usefulness of repeated echocardiography
Infective endocarditis (IE) is most often caused by alpha-hemolytic streptococci or Staphylococcus aureus and is characterized by the presence of vegetations on the heart valves. Here we present a case of IE caused by Streptococcus pyogenes, a distinctly uncommon IE-pathogen, where no vegetations could be visualized on repeated echocardiography. Diagnosis was instead evident from septic embolizati
Economic evaluation of diabetes prevention interventions in Bangladesh : A modelling study
Aim: To model the long-term cost-effectiveness of scaling up two prevention interventions against type 2 diabetes mellitus (T2DM), i.e. community mobilisation through participatory learning and action (PLA) and mHealth mobile phone messaging, implemented in rural Bangladesh as part of the “DMagic” trial. Methods: A health-economic Markov model of the three-arm, cluster-randomised controlled DMagic
National implementation of vaginal Natural Orifice Transluminal Endoscopic Surgery for benign hysterectomies : A historical cohort study of Swedish data 2021–2023
Introduction: Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a technique combining vaginal entrance to the abdomen with endoscopic overview. Previous studies have shown that vNOTES decreases operating time, hospitalization, postoperative complications, and pain. We aimed to present patient demographics, costs, and surgical outcomes following the implementation of vNOTES for be
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease
BACKGROUND: Human induced pluripotent stem cells (hiPSCs) have been proposed as an alternative source for cell replacement therapy for Parkinson's disease (PD) and they provide the option of using the patient's own cells. A few studies have investigated transplantation of patient-derived dopaminergic (DA) neurons in preclinical models; however, little is known about the long-term integrity and fun
Telomeres in ecology and evolution : A review and classification of hypotheses
Research on telomeres in the fields of ecology and evolution has been rapidly expanding over the last two decades. This has resulted in the formulation of a multitude of, often name-given, hypotheses related to the associations between telomeres and life-history traits or fitness-facilitating processes (and the mechanisms underlying them). However, the differences (or similarities) between the var
