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Poly(propylene imine) dendrimers have been shown to be promising 3-dimensional polymers for the use in the pharmaceutical and biomedical applications. Our aims of this study were first, to synthesize a novel type of dendrimer with poly(propylene imine) core and maltose-histidine shell (G4HisMal) assessing if maltose-histidine shell can improve the biocompatibility and the ability to cross the bloo
Lemierre syndrome usually affects otherwise healthy adolescents or young adults and occurs at an overall rate of 1 to 10 cases per million person-years with an estimated fatality rate of 4 to 9%. Diagnostic criteria remain debated and include acute neck/head bacterial infection (often tonsillitis caused by anaerobes at high potential for sepsis and vascular invasion, notably Fusobacterium necropho
The study of molecular dynamics involves observations of the motion of nuclei and electrons. While nuclear motion is usually on the picosecond or femtosecond timescale, attosecond precision is necessary to directly observe the motion of electrons. Ultrashort laser pulses have become established as a viable tool for probing femtosecond dynamics by irradiating the target for only extremely short tim
Improved industrial energy efficiency is a cornerstone in climate change mitigation. Research results suggest that there is still major untapped potential for improved industrial energy efficiency. The major model used to explain the discrepancy between optimal level of energy efficiency and the current level is the barrier model, e.g., different barriers to energy efficiency inhibit adoption of c
A new electricity-production concept attracted massive media attention in Sweden during 2008 when companies be-gan marketing small-scale photovoltaic panels (PVs) and microwind turbines. The products were launched by their simplicity: the components are so easy to install that anyone can do it. How, then, do households perceive these products? Why would households choose to buy them? What do house
Assessment of breast density at the point of mammographic examination could lead to optimized breast cancer screening pathways. The onsite breast density information may offer guidance of when to recommend supplemental imaging for women in a screening program. A software application (Insight BD, Siemens Healthcare GmbH) for fast onsite quantification of volumetric breast density is evaluated. The
The objective was to design a thin, flex card based personal dosemeter with low angular and energy dependence. It is based on silicon diodes that can measure the personal dose equivalent. Anisotropic conducting adhesive was used to connect the Si sensor to the flex card. Its intended use is for interventional radiology and after nuclear or radiological accidents, as it provides immediate detailed
Carotenoid-based coloration in birds is widely considered an honest signal of individual condition, but the mechanisms responsible for condition dependency in such ornaments remain debated. Currently, the most common explanation for how carotenoid coloration serves as a reliable signal of condition is the resource trade-off hypothesis, which proposes that use of carotenoids for ornaments reduces t
The transition to a Circular Economy (CE) requires enabling conditions that remove existing barriers in product life extension and material recovery operations. This contribution investigates barriers to material resource efficiency strategies in the maritime sector in Scandinavia and discusses the potential of policy interventions to enable increased reuse and remanufacturing of ship components.
Depression is one of the most common health problems worldwide but is often undertreated. Internet-delivered cognitive behavioral therapy (ICBT) appears to be an effective treatment option, with the potential to reach a larger proportion of individuals suffering from depression. While many studies have examined the efficacy of ICBT for depression in randomized controlled trials, fewer have focused
In extending the analysis of the four secular resonances between close orbits in Li and Christou (Celest Mech Dyn Astron 125:133–160, 2016) (Paper I), we generalise the semianalytical model so that it applies to both prograde and retrograde orbits with a one-to-one map between the resonances in the two regimes. We propose the general form of the critical angle to be a linear combination of apsidal
To investigate how manufacturing errors affect the gear set, a method is developed to calculate the contact stress of a gear set with pitch and involute incline errors. The method is parametric, and a hybrid model is used to model the gear stiffness. Contact outside the line of action is considered.A numerical example is used to show how manufacturing errors can change the contact pressure and cau
Large Eddy Simulation (LES) of an incompressible, turbulent, co-annular swirling flow field have been performed in order to compare the influence of different subgrid scale (SGS) models. Two models were investigated, an implicit model and a stress similarity model. In the simulations using the implicit approach, no explicit SGS model was used. For the stress similarity model, similar behaviour bet
Context: Open tools (e.g., Jenkins, Gerrit and Git) offer a lucrative alternative to commercial tools. Many companies and developers from OSS communities make a collaborative effort to improve the tools. Prior to this study, we developed an empirically based theory for companies’ strategic choices on the development of these tools, based on empirical observations in the telecom domain. Aim: The ai
