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The ESS Linac project, phase I, requires 12 long pulse klystron modulators with compact footprint, high pulse power and improved quality both on the output pulse waveform and on the input AC power line. Conventional long pulse modulators are typically based on HV pulse transformers and commonly exhibit poor efficiency, low power density, large footprint and cost, with still limited performance on
A new method to determine the concentration of the free protein S in plasma is described. It is an enzyme-linked ligandsorbent assay (ELSA) which utilises the protein S binding capacity of the natural ligand C4b-binding protein (C4BP) to capture the free protein S from plasma samples. The use of C4BP as ligand in the assay is possible due to the high affinity (Kd = 0.1 nM) of the interaction betwe
In 2015 Afghans were the second largest group of asylum seekers in Sweden (and Europe). In this article, I analyze interviews conducted in early 2017 in Scania County with six adult male Afghan asylum seekers, an executive officer at the Swedish Migration Agency, the head of a private asylum seeker camp, and a voluntary worker. I show how the asylum seekers made their way to Sweden not so much thr
The paper presents results from a comparative study of selected biological and technical functions for thermal adaptability, which are based on an extensive literature review in biology and façade engineering. Several selected biological role models have been analysed in detail to identify their principles for dealing with thermal adaptation. These principles have been further abstracted through s
Background: Galectin 3 and ST2 are mediators and biomarkers of myocardial fibrosis and remodeling that have recently entered the clinical practice guidelines as prognostic factors in heart failure patients. Elevated galectin 3 and ST2 levels in acute myocardial infarction patients have also been associated with increased incidence of adverse events during follow-up. Purpose: We aimed to assess the
Phosphorylation is a protein post-translational modification (PTM) that plays an important role in cell signaling, cell differentiation, and metabolism. The hyper phosphorylated forms of certain proteins have been appointed as biomarkers for neurodegenerative diseases, and phosphorylation-related mutations are important for detecting cancer pathways. Due to the low abundance of phosphorylated prot
Academic teacher development is an educational meeting place for academics already practising the art of teaching. Yet, it is in courses for this development that academics are supposed to be taught how to teach and how to improve their teaching skills. In my article I propose a new conceptual methodological framework for teaching teachers how to teach – Didactic Reasoning. Its foundation can be t
Background: Quality of supervision is a major predictor for successful PhD projects. A survey showed that almost all PhD students in the Health Sciences in Denmark indicated that good supervision was important for the completion of their PhD study. Interestingly, approximately half of the students who withdrew from their program had experienced insufficient supervision. This led the Research Educa
Summary: Background: In 2014, the Swedish Association of Clinical Physiology recommended the use of a new reference material for exercise capacity in bicycle exercise stress testing, 'the Kalmar material'. Compared to the formerly used reference material, 'the Kristianstad material', an increase in the amount of patients being classified as having decreased exercise capacity was expected, but the
Do Chinese cities compete for investments with lax environmental law enforcement? The here presented study suggests that this is true for some municipalities but not all of them. Based on data for 126 key environmental protection cities and regional economic hubs between 2010 and 2012 we show that economic decentralization and political centralization both shape spatial patterns of compliance with
The gut microbiome of animals is emerging as an important factor influencing ecological and evolutionary processes. A major bottleneck in obtaining microbiome data from large numbers of samples is the time-consuming laboratory procedures required, specifically the isolation of DNA and generation of amplicon libraries. Recently, direct PCR kits have been developed that circumvent conventional DNA e
Complement is crucial to the immune response, but dysregulation of the system causes inflammatory disease. Complement is activated by three pathways: classical, lectin, and alternative. The classical and lectin pathways are initiated by the C1r/C1s (classical) and MASP-1/MASP-2 (lectin) proteases. Given the role of complement in disease, there is a requirement for inhibitors to control the initiat
The number of triangulations of a planar n point set S is known to be cn, where the base c lies between 2.43 and 30. Similarly, the number of crossing-free spanning trees on S is known to be dn, where the base d lies between 6.75 and 141.07. The fastest known algorithm for counting triangulations of S runs in 2(1+o(1))nlog n time while that for counting crossing-free spanning trees runs in O (7.12
Background and Aims: There are limited data on the potential role of preoperative non-invasive markers, specifically the aspartate-to-alanine aminotransferase ratio and the aspartate aminotransferase-to-platelet ratio index, in predicting perioperative liver-related complications after hepatectomy for colorectal cancer metastases. Methods: Patients undergoing liver resection for colorectal cancer
Background & Aims Predniso(lo)ne, alone or in combination with azathioprine, is the standard-of-care (SOC) therapy for autoimmune hepatitis (AIH). However, the SOC therapy is poorly tolerated or does not control disease activity in up to 20% of patients. We assessed the efficacy of mycophenolate mofetil (MMF) and tacrolimus as second-line therapy for patients with AIH. Methods We performed a r
A multiple-input-multiple-output (MIMO) dual-band antenna system consisting of two elements, each of which built up of circularly polarized slotted patch antenna for mm-wave band 5G wireless handheld and portable terminals is described. Space diversity is used to achieve a good independent channel fading in MIMO systems. In theoretical analysis of MIMO systems often assume that each antenna is iso
