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Vertigo is one of the most common complaints in medicine. Despite its high prevalence, patients with vertigo often receive either inappropriate or inadequate treatment. The most important reasons for this deplorable situation are insufficient interdisciplinary cooperation, nonexistent standards in diagnostics and therapy, the relatively rare translations of basic science findings to clinical appli
Medulloblastomas comprise a heterogeneous group of tumours and can be subdivided into four molecular subgroups (WNT, SHH, Group 3 and Group 4) with distinct prognosis, biological behaviour and implications for targeted therapies. Few experimental models exist of the aggressive and poorly characterized Group 3 tumours. In order to establish a reproducible transplantable Group 3 medulloblastoma mode
Exploratory synthesis in the area of polar intermetallics has yielded a rich variety of structures that offer clues into the transition in bonding between Zintl and Hume-Rothery phases. In this article, we present a bonding analysis of one such compound, Ca10Pt7Si3, whose large Ca content offers the potential for negative formal oxidation states on the Pt. The structure can be divided into a subla
Microstructure imaging techniques based on tensor-valued diffusion encoding have gained popularity within the MRI research community. Unlike conventional diffusion encoding—applied along a single direction in each shot—tensor-valued encoding employs diffusion encoding along multiple directions within a single preparation of the signal. The
Humor is essential to social life, but it is often overlooked in the study of crime and other social problems. We introduce and make use of humor theory, emphasizing the theories of superiority and relief. Based on interviews with incarcerated men, we demonstrate how humor is used to criticize authorities, for self-aggrandizement, and to alleviate the pain of tragic experiences. Funny remarks and
The paper suggests conditions for presence of quadratic Lyapunov functions for nonlinear observer based feedback systems with an 'input nonlinearity' in the feedback path. Provided that the system using state feedback satisfies the Circle Criterion (i.e., when all states can be measured), we show that the extended system with only output feedback control from a (full state) Luenberger-type observe
The growth of a planetary core by pebble accretion stops at the so-called pebble isolation mass, when the core generates a pressure bump that traps drifting pebbles outside its orbit. The value of the pebble isolation mass is crucial in determining the final planet mass. If the isolation mass is very low, gas accretion is protracted and the
Botulinum neurotoxins (BoNTs), the most potent toxins known, are potential bioterrorism agents. It is well established that all seven serotypes of BoNTs (BoNT/A-G) require complex gangliosides as co-receptors. Here, we report that BoNT/DC, a presumed mosaic toxin between BoNT/D and BoNT/C1, binds and enters efficiently into neurons lacking complex gangliosides and shows no reduction in toxicity in
The Absolut Company har öppnat besökscentret Absolut Home i Åhus och detta har potential att medföra ett stort antal värden för orten. Forskarna har studerat bådeturistaktörers och Åhusbors syn på värden för att ta reda på hur de ställer sig till det nya besökscentret i sin ort.
Atmospheric new particle formation (NPF) is an important phenomenon in terms of global particle number concentrations. Here we investigated the frequency of NPF, formation rates of 10 nm particles, and growth rates in the size range of 10–25 nm using at least 1 year of aerosol number size-distribution observations at 36 different locations around the world. The majo
For a firm in an open source software (OSS) ecosystem, the requirements engineering (RE) process is rather multifaceted. Apart from its typical RE process, there is a competing process, external to the firm and inherent to the firm’s ecosystem. When trying to impose an agenda in competition with other firms, and aiming to align internal product planning with the ecosystem’s RE process, firms need
The new di- and tetranuclear Fe(III) μ-oxido complexes [Fe 4 (μ-O) 4 (PTEBIA)
A new carbon isotope record with conodont biostratigraphy is presented for the entire Early Triassic from the Musandam Peninsula, United Arab Emirates (UAE). This is a near-continuous and exclusively shallow marine carbonate succession that allows analysis of a high-resolution primary carbon cycling signature in the absence of significant depth-dependent or lithologic controls. The Musandam carbon
Humans require multiple services from ecosystems, but it is largely unknown whether trade-offs between ecosystem functions prevent the realisation of high ecosystem multifunctionality across spatial scales. Here, we combined a comprehensive dataset (28 ecosystem functions measured on 209 forest plots) with a forest inventory dataset (105,316 plots) to extrapolate and map relationships between vari
Aims of the study: Neurological impairment after resuscitated cardiac arrest (CA) remains a significant unmet medical need. Brain ischemia associated with CA and subsequent reperfusion is evident as two fundamentally different types of damage on neuropathological examination: frank necrosis (involving all cell types) and selective eosinophilic neuronal death (SEND). These types of damage are not o
