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This article presents a polar diagram method developed for describing and evaluating the potential machinability of different workpiece materials. The potential machinability is examined in terms of five critical properties of the workpiece material. Two groups of materials, a group of common steel grades and the other a group of stainless steels, were examined in detail, their polar diagrams illu
Purpose – The aim of this study is to test the assumption that ability to handle communication and liability of newness (LoN) is enhanced by academic entrepreneurship education and/or previous start‐up experience. Design/methodology/approach – The data collection includes a questionnaire with a total sample of 392 responding entrepreneurs in Sweden. Statistical analyses are made between entrepren
Accounting for bioenergy's carbon dioxide (CO2) emissions, as done under the Kyoto Protocol (KP) and European Union (EU) Emissions Trading Scheme, fails to capture the full extent of these emissions. As a consequence, other approaches have been suggested. Both the EU and United States already use value-chain approaches to determine emissions due to biofuels - an approach quite different from that
The limit of detection of low-molecular weight compounds in tissue sections, analyzed by matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI), was significantly improved by employing sample washing using a pH-controlled buffer solution. The pH of the washing solutions were set at values whereby the target analytes would have low solubility. Washing the tissue sections
The nexus of population growth and changing diets has increased the demands placed on agriculture to supply food for human consumption, animal feed and fuel. Rising incomes lead to dietary changes, from staple crops, towards commodities with greater land requirements, e.g. meat and dairy products. Despite yield improvements partially offsetting increases in demand, agricultural land has still been
Understanding the role of electrostatics in protein stability requires knowledge of these interactions in both the folded and unfolded states. Electrostatic interactions can be probed experimentally by characterizing ionization equilibria of titrating groups, parameterized as pK(a) values. However, pK(a) values of the unfolded state are rarely accessible under native conditions, where the unfolded
The main objective of this study was to investigate the risk of type 1 diabetes mellitus (T1D) in children exposed to tobacco smoking in utero, also taking genetic predisposition as expressed by HLA haplotype into account. In Skåne, the southernmost county of Sweden, all children born 1999-2005 who developed T1D were registered, resulting in 344 cases. For each child with T1D, three control childr
The neural correspondence between the systems responsible for the execution and recognition of actions has been suggested both in humans and non-human primates. Apart from being a key region of this visuo-motor observation-execution matching (OEM) system, the human inferior frontal gyrus (IFG) is also important for speech production. The functional overlap of visuo-motor OEM and speech, together w
Androgen deprivation therapy (ADT) is first-line treatment for metastatic prostate cancer (PCa). Gonadotrophin-releasing hormone (GnRH) agonists are the most commonly used ADT but have several theoretical physiologic disadvantages (e.g. initial testosterone surge, potential microsurges upon repeat administration). Testosterone surge delays the intended serologic endpoint of testosterone suppressio
The Ordovician Period includes two major macroevolutionary events: the Great Ordovician Biodiversification Event (GOBE) and the Late Ordovician Mass Extinction (LOME), alongside a fundamental climate transition from a greenhouse to an icehouse state. Although both biological events occurred during relatively short-term global cooling conditions, their starkly contrasting biotic responses remain po
PURPOSE: Provision of adequate support is much needed to secure equal educational opportunities for students with developmental language disorder (DLD). Important perspectives on support provision and its impact on academic progress are held by school professionals, caregivers, and students with DLD. This study sought to further the current knowledge on the perceived relation between educational s
This paper introduces a novel dataset that serves as a prototype of what we call the ‘Job Ads Database’ (JADB). The underlying job advertisements are gathered from the Swedish digitalized newspaper corpus hosted by and made accessible through the Swedish National Library (Kungliga Biblioteket). JADB enables studying how the frequency and content of job advertisements change over time and sheds new
Background and purpose: Stereotactic radiosurgery (SRS) requires high positional accuracy to safely deliver large doses. This study evaluated an integrated surface- and image-guided radiotherapy (SGRT-IGRT) system by analysing (1) the agreement between thermo-optical and stereoscopic X-ray positioning, and (2) the impact of intra-fractional workflows on treatment accuracy and time. Materials and m
We show exponential lower bounds on resolution proof length for pigeonhole principle (PHP) formulas and perfect matching formulas over highly unbalanced, sparse expander graphs, thus answering the challenge to establish strong lower bounds in the regime between balanced constant-degree expanders as in [Ben-Sasson and Wigderson’01] and highly unbalanced, dense graphs as in [Raz’04] and [Razborov’03
Background: Technetium-99 m-dimercaptosuccinic acid (DMSA) renal cortical scintigraphy is commonly used in the evaluation of children with urinary tract infections. Pyelonephritis and post-pyelonephritic scarring manifest as renal cortical defects on DMSA renal scintigraphy, including DMSA Single Photon Emission Computed Tomography (SPECT) imaging. SPECT image quality can be degraded by blurring r
Blood biomarkers have emerged as accurate tools for detecting Alzheimer’s disease (AD) pathology, offering a minimally invasive alternative to traditional diagnostic methods such as imaging and cerebrospinal fluid (CSF) analysis. Yet, the logistics surrounding venipuncture for blood collection, although considerably simpler than the acquisition of imaging and CSF, require precise processing and st
Europe’s Beating Cancer Plan is a substantial European Union (EU) investment into cancer prevention and treatment. Integration of genetic services towards personalised cancer prevention and care is a flagship of this plan. Genetic counselling is critical to this integration, facilitating informed patient decision making and improved clinical management. However, growing demands for genetic testing
We explore mission assignment and task offloading in Open Radio Access Network (Open RAN)-enabled intelligent transportation systems (ITS), where autonomous vehicles utilize mobile edge computing for efficient processing. Existing studies often overlook mission dependencies and offloading costs, leading to suboptimal decisions. To address this, we formulate a novel optimization problem that integr
The development of sensitive, convenient, and cost-effective methods for detecting disease biomarkers is very important for meeting the growing demand for early clinical diagnosis. Additionally, the detection of disease biomarkers at ultralow concentrations is very important for disease prevention and treatment and posttreatment rehabilitation. However, current ultrasensitive detection strategies
