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Background & Purpose: Radiation therapy is an essential treatment for cancer patients with the ultimate goal to deliver radiation doses to the tumour with precision while minimizing exposure to surrounding healthy tissues. Treatment verification is crucial to ensure the accuracy of radiation delivery, for instance by measuring the radiation dose distribution. Among various dosimetry techniques
For Those About to Rock... – A study of views of the ensemble repertoire in the aesthetic programme in Swedish high schools In my paper I will present the result of an inquiry made in the aesthetic program in Swedish high schools. The survey covers nine different groups in three different schools in Skåne. As background to my study I have used experiences I have had during my practical workplace t
Complex diseases are caused by a combination of genetic, lifestyle, and environmental factors and comprise common noncommunicable diseases, including allergies, cardiovascular disease, and psychiatric and metabolic disorders. More than 25% of Europeans suffer from a complex disease, and together these diseases account for 70% of all deaths. The use of genomic, molecular, or imaging data to develop
This chapter delves into the challenges encountered by victims of human trafficking and other forms of labour exploitation in Sweden as they struggle to access social rights and justice. By drawing from theories of victimisation as an interactional process, the study examines the role of professionals such as government agents, social services, unions, and NGOs as facilitators in assisting victimsThis chapter delves into the challenges encountered by victims of human trafficking and other forms of labour exploitation in Sweden as they struggle to access social rights and justice. By drawing from theories of victimisation as an interactional process, the study examines the role of professionals such as government agents, social services, unions, and NGOs as facilitators in assisting victims
Purpose: The majority of women with ovarian cancer are diagnosed in late stages. Most women do have symptoms prior to diagnosis, sometimes several months before the diagnosis. The aim of this study was to evaluate the timeline from the first presentation of symptoms to a physician until there is a reasonable suspicion of cancer, among women diagnosed with advanced stage ovarian cancer. We wanted t
A novel metabolomic method based on gas chromatography-mass spectrometry was applied to investigate serum metabolites in response to dietary Gln supplementation in piglets. Sixteen, 21-d-old pigs were weaned and assigned randomly to 2 isonitrogenous diets: 1) Gln diet, which contained 1% L-Gln (as-fed basis), and 2) control diet, which contained LAla to make this diet isonitrogenous with the Gln d
BACKGROUND: To benefit from available care and treatment options, patients should first be counselled and tested for HIV. Our aim was to assess the acceptability of HIV testing among tuberculosis patients under routine care conditions in south Ethiopia.METHODS: We interviewed all adult tuberculosis patients who were treated at Arba Minch Hospital in Ethiopia between January and August 2005. After
A promise of genomics in precision medicine is to provide individualized genetic risk predictions. Polygenic risk scores (PRS), computed by aggregating effects from many genomic variants, have been developed as a useful tool in complex disease research. However, the application of PRS as a tool for predicting an individual's disease susceptibility in a clinical setting is challenging because PRS t
Parkinson’s disease (PD) is a complex, progressive neurological condition that impacts daily life and reduces life satisfaction (LS). To achieve and maintain high LS, persons with PD (PwPD) must go through a process of change to adapt to their new life situation. However, our knowledge about this process is very limited. The aim of this study was to investigate the process of change, and the main
Analysis of the genomic landscape of prostate cancer has identified different molecular subgroups with relevance for novel or existing targeted therapies. The recent approvals of the poly(ADP-ribose) polymerase (PARP) inhibitors olaparib and rucaparib in the metastatic castration-resistant prostate cancer (mCRPC) setting signal the need to embed molecular diagnostics in the clinical pathway of pat
Conservation efforts have mainly been focused on depleted species or populations, but many formerly reduced marine mammal populations have recovered to historical abundances. This calls for new management strategies and new models for ecological risk assessment that incorporate local density dependence and multiple environmental stressors. The harbor seal metapopulation in Swedish and Danish water
OBJECTIVE: To identify and characterize genetic loci associated with the risk of developing anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV).METHODS: Genetic association analyses were performed after Illumina sequencing of 1,853 genes and subsequent replication with genotyping of selected SNPs in a total cohort of 1110 Scandinavian cases with granulomatosis with polyangiit
A library of donor-acceptor system consisting of cyclopentadithiophene-based polymer photocatalysts have been designed and synthesized. Among all photocatalysts, the active PCPDTBSO achieved hydrogen evolution rates of 24.6 mmol h–1 g–1 with apparent quantum yields of 8.7 % at 500 nm. More importantly, combined the results of photocatalytic efficiency, apparent quantum yield, the time-resolved flu
Increasingly, scholarly debates and policy developments on citizen participation in energy transitions have included calls for ‘energy democracy’ and active forms of ‘energy citizenship’. The concepts are tightly connected to the debate on energy transition, and the need for a decentralised energy system, based on renewable energy and increased local energy ownership. The two concepts exist in par
Many exemplary projects have demonstrated that Nature-based Solutions (NBS) can contribute to climate change adaptation, but now the challenge is to scale up their use. Setting realistic policy goals requires knowing the amount of different NBS types that can fit in the urban space and the benefits that can be expected. This research aims to assess the potential for a full-scale implementation of
Semiconductor double quantum dots (DQD) coupled to superconducting microwave resonators offer a promising platform for the detection of single microwave photons. In previous works, the photodetection was studied for a monochromatic source of microwave photons. Here, we theoretically analyze the photodetection of single microwave pulses. The photodetection in this case can be seen as a nonlinear fi
Drug-resistant bacterial infections are among the most severe physiological challenges facing human health. Therefore, the detection and inactivation of pathogenic bacteria remains a crucial therapeutic goal in modern society. In this study, we design multifunctional nanocomposites aimed at bacterial binding, fluorescence labeling, and synergistic antibacterial treatment. These nanocomposites are
Induced pluripotent stem cells (iPSCs) have significant potential for disease modeling and cell therapies. However, their wide-spread application has faced challenges, including batch-to-batch variabilities, and notable distinctions when compared to embryonic stem cells (ESCs). Some of these disparities can stem from using undefined culture conditions and the reprogramming procedure, however, the
