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T helper 17 (T H17) cells located at the Peyer's patch (PP) inductive site and at the lamina propria effector site of the intestinal immune system are responsive to both pathogenic and commensal bacteria. Their plasticity to convert into follicular helper T (T FH) cells has been proposed to be central to gut immunoglobulin A (IgA) responses. Here, we used an IL-17A fate reporter mouse and an MHC
This paper presents a search for a new Z′ vector gauge boson with the ATLAS experiment at the Large Hadron Collider using pp collision data collected at s = 13 TeV, corresponding to an integrated luminosity of 139 fb −1. The new gauge boson Z′ is predicted by Lμ − Lτ models to address observed phenomena that can not be explained by the Standard Model. The search examines the four-muon (4μ) final s
What difference can local participation make in a world where inequality increases everywhere, where segregation pulls communities apart and where policymakers marginalise the needs and interests of the people whose lives their decisions affect the most? This question was central two decades ago when research on participatory institutions took off. Leftist scholars described participatory budgetinWhat difference can local participation make in a world where inequality increases everywhere, where segregation pulls communities apart and where policymakers marginalise the needs and interests of the people whose lives their decisions affect the most? This question was central two decades ago when research on participatory institutions took off. Leftist scholars described participatory budgetin
This article presents the results of survey-based research which explores if licensed aircraft maintenance engineers working in Norway, Sweden, and Portugal experience regulated “just culture” as procedural justice-infused processes when occurrence reporting in European Union (EU) civil aviation. Drawing on Tylerian procedural justice theory, the study finds that, perceived procedural justice is m
Since January 1, 2005 all publicly traded companies within the EU must prepare their consolidated financial statements in accordance with International Financial Reporting Standards (IFRS). The transition to IFRS brought with it major changes in the accounting for financial instruments through the introduction of the highly controversial accounting standard IAS 39 Financial Instruments: Recognitio
Chlorophyllide a is a metabolite late in the biosynthesis of chlorophylls and bacteriochlorophylls. Isolation procedures for chlorophyllide a from Rhodobacter capsulatus CB1200 and barley (Hordeum vulgare L.) are described and compared. R. capsulatus CB1200 is a double mutant in the bacteriochlorophyllide a biosynthetic pathway, and chlorophyllide a is excreted by the cells when grown in Tween 80-
Inverse modeling techniques used to quantify surface carbon fluxes commonly assume that the uncertainty of fossil fuel CO2 (FFCO2) emissions is negligible and that intra-annual variations can be neglected. To investigate these assumptions, we analyzed the differences between four fossil fuel emission inventories with spatial and temporal differences over Europe and their impact on the model simula
Innovative engineering methods are needed to enhance the adaptability and agility of industrial control procedures and concurrently manage their rising complexity. Service-oriented Architecture (SOA) constitutes a promising paradigm to meet these challenges. To apply the rather abstract SOA principles to industrial automation, a model-driven engineering method is presented in this paper. Therefore
High material penetration by neutrons allows for experiments using sophisticated sample environments providing complex conditions. Thus, neutron imaging holds potential for performing in situ nondestructive measurements on large samples or even full technological systems, which are not possible with any other technique. This paper presents a new sample environment for in situ high resolution neutr
Species diversity in sandy grasslands is threatened by decalcification and eutrophication. To determine the most appropriate conditions for red-listed gasteromycete fungi in such grasslands, we investigated their pH preferences in this habitat in southern Sweden. During two winters soil samples were collected from the vicinity of mycelia of these species. Chemical analysis revealed that none of th
Corridors are often considered to promote dispersal between habitat patches. In this paper, we study whether or not corridors induce colonisation of nunataks (ice-free areas in glacier surroundings) by promoting dispersal from lowland to the nunataks. On outlet glaciers, debris originating from nunataks forms the so-called medial moraines that stretch from the nunataks down-glacier to the lowland,
The target for the oral erectile dysfunction drugs, phosphodiesterase type 5 (PDE5) inhibitors, is part of a pathway implicated in the development of malignant melanoma. An increased risk of melanoma in sildenafil users was recently reported.
A coupled diffusion-deformation, multiphase field model for elastoplastic materials is presented. The equations governing the evolution of the phase fields and the molar concentration field are derived in a thermodynamically consistent way using microforce balance laws. As an example of its capabilities, the model is used to study the growth of the intermetallic compound (IMC) Cu6Sn5 during room-t
The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Homozygous FVL and PTM have long been feared conditions thought to cause high rates of morbidity and mortality. To analyse clinical features in patients with homozygous FVL and PTM, as well as patients with double heterozygosity for FVL and PTM. All patients with homozygous FVL, PTM or double
This paper investigates how classical measurement error and additive outliers (AO) influence tests for structural change based on F-statistics. We derive theoretically the impact of general additive disturbances in the regressors on the asymptotic distribution of these tests for structural change. The small sample properties in the case of classical measurement error and AO are investigated via Mo
Background Riks-Stroke, the Swedish Stroke Register, is the world's longest-running national stroke quality register (established in 1994) and includes all 76 hospitals in Sweden admitting acute stroke patients. The development and maintenance of this sustainable national register is described. Methods Riks-Stroke includes information on the quality of care during the acute phase, rehabilitation a
A novel set up composed of an anaerobic biofilm reactor followed by ozonation was used for treatment of artificial and real textile effluents containing azo dyes. The biological treatment efficiently removed chemical oxygen demand and color. Ozonation further reduced the organic content of the effluents and was very important for the degradation of aromatic compounds, as shown by the reduction of
This paper presents an approximation model for optimizing reorder points in one-warehouse N-retailer inventory systems subject to highly variable lumpy demand. The motivation for this work stems from close cooperation with a supply chain management software company, Syncron International, and one of their customers, a global spare parts provider. The model heuristically coordinates the inventory s
The Environmental Determinants of Diabetes in the Young (TEDDY) Study aims at examining the associations between islet autoimmunity and various environmental exposures (e.g. diet) in Finland, Germany, Sweden and the United States (US). In order to produce comparable results from dietary assessments, the national food composition databases (FCDB) must contain mutually comparable food composition da
Knowledge of subcellular localizations (SCLs) of plant proteins relates to their functions and aids in understanding the regulation of biological processes at the cellular level. We present PlantLoc, a highly accurate and fast webserver for predicting the multi-label SCLs of plant proteins. The PlantLoc server has two innovative characters: building localization motif libraries by a recursive meth
