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Wear properties of cemented carbides with new binder solutions for rock drilling inserts

Cemented carbides with tungsten carbide grains as hard phase and metallic cobalt binder phase are used extensively for drill bit inserts for rock drilling. The process of rock drilling is severe with some of the wear happening through fracture in the cemented carbide. This work investigated two cemented carbides with iron rich alternative binder phases containing different amounts of FCC phase, in

Adding salt to foods and risk of metabolic dysfunction-associated steatotic liver disease and other chronic liver diseases

PURPOSE: Adding salt to foods, a novel indicator for studying habitual sodium intake, has been positively associated with multiple diseases and mortality. However, little is known about its association with liver-related disorders. This study aimed to investigate the associations of adding salt to foods with risks of metabolic dysfunction-associated steatotic liver disease (MASLD), cirrhosis, and

Predictors of abdominal aortic aneurysm progression in men with small infrarenal aortic diameters at screening

Objective: Screening for abdominal aortic aneurysm (AAA) defined as an infrarenal aortic diameter (IAD) of ≥30 mm reduces mortality, but managing patients with diameters of 25 to 29 mm is debated. Incorporating body surface area into the diagnostic criteria may improve the identification of those at risk of developing treatment-requiring aneurysms in this group. In a previous study, we defined a r

Self-reported sleep disturbances and its determinants in people 1 year or more after stroke : A cross-sectional study

Background: Survivors of stroke commonly report sleep disturbances. Studies of sleep disturbances after stroke are mostly performed in the acute phase. An increased knowledge of sleep disturbances and its determinants a longer time after stroke is needed to improve treatment and rehabilitation. Objective: To assess survivors of stroke more than 1 year after stroke onset and (1) investigate self-re

“It is very convenient when it works – successes and challenges with welfare technology” - a qualitative study

Welfare technology (WT) use is increasingly advocated to facilitate aging in place. However, it remains unclear how older adults and homecare staff perceive these digital technologies in practice. This qualitative study investigated the ways in which current WT either facilitated or fell short in supporting older adults in their daily lives and homecare staff at work. Four key themes were develope

Therapeutic S100A8/A9 inhibition reduces NADPH oxidase expression, reactive oxygen species production and NLRP3 inflammasome priming in the ischemic myocardium

Oxidative stress and alterations in redox signalling have been implicated in the pathophysiology of myocardial infarction (MI). NADPH oxidase (Nox) is an important source of reactive oxygen species (ROS) in the infarcted myocardium. Alarmin S100A8/A9 amplifies acute myocardial inflammation in MI and has been shown to be a promising therapeutic target to improve cardiac function post-MI. We aimed t

Functional-gradient WC-TiC cemented carbides with alternative binders (Ni and Fe)

In this work we investigate the development of functionally graded cemented carbides, featuring macro gradients on the millimeter scale, where Fe, or Ni is the binder phase. Two composites, WC-Ni and WC-Fe with 20 % binder by volume were produced by addition of TiC on the surface of the samples before sintering at 1475 °C for 1 h. The sintered samples were analyzed using electron microscopy and mi

Mechanically Robust Supercrystals from Antisolvent-Induced Assembly of Perovskite Nanocrystals

Ordered arrays of nanocrystals, called supercrystals, have attracted significant attention owing to the collective quantum effects arising from the coupling between neighboring nanocrystals. In particular, lead halide perovskite nanocrystals are widely used because of the combination of the optical properties and faceted cubic shape, which enables the formation of highly ordered supercrystals. The

Methods for Vulnerability Analysis of Power Systems

Power systems are a vital infrastructure for the functioning of the society, generally regarded as one of the most critical infrastructures. Past power system blackouts (e.g., the Canadian ice-storm and New-Zeeland Power outage in 1998, the U.S. blackout in 2003, the European blackout in 2006 and the Indian blackout in 2012) have revealed the inherent vulnerabilities of power systems as well as th

Adherence to the EAT-lancet dietary pattern among older adults in Rwanda and its association with micronutrient intake

BACKGROUND: Sub-Saharan Africa is facing a dietary transition with both undernutrition and rising rates of non-communicable diseases. Adopting the reference diet proposed by the EAT-Lancet Commission can reduce both the environmental burden and improve health outcomes. However, whether this diet provides micronutrient adequacy in older adults in low-income settings has not been investigated. This

Identifying genetic variants associated with sugar intake and appraising the genetic correlations with cardiovascular outcomes

BACKGROUND: The evidence linking sugar intake to cardiovascular disease risk remains largely inconclusive, with variations observed across different subgroups of sugar intake. In addition, studies on genetic markers of sugar intake are scarce, especially for different sugar subgroups.OBJECTIVE: This genome-wide association study (GWAS) aimed to investigate genetic variants associated with the inta

Preserved ratio impaired spirometry, plasma proteomics, and incident heart failure

INTRODUCTION: Epidemiological evidence suggests the association of preserved ratio impaired spirometry (PRISm) at baseline with the risk of heart failure (HF), however, the associations between transitions of PRISm and incident HF remain to be clarified. Furthermore, the causal relationship and underlying biological mechanisms linking PRISm and HF are unclear.OBJECTIVES: This study aimed to invest

Weight-adjusted-waist index, estimated glucose disposal rate, C-reactive protein, and mortality risks among individuals with type 2 diabetes : 2 prospective cohort studies in China and the United Kingdom

BACKGROUND: Weight-adjusted-waist index (WWI) is an anthropometric index reflecting fat mass and muscle mass, both of which are important factors influencing insulin resistance and inflammation.OBJECTIVES: We aimed to examine the associations of WWI with all-cause, cardiovascular, and noncardiovascular mortality among individuals with type 2 diabetes (T2D) and further investigate whether insulin r