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Background: Data on the relationship between body mass index (BMI), thromboembolic events (TEE) and bleeding in patients with atrial fibrillation (AF) are controversial, and further evidence on the risk of such events in obese patients with AF receiving different anticoagulant therapies (OAC) is needed. Methods and results: We divided a total of 9330 participants from the prospective PREFER in AF

Asparagine-linked glycosylation 13 homolog (ALG13) encodes a nonredundant, highly conserved, X-linked uridine diphosphate (UDP)-N-acetylglucosaminyltransferase required for the synthesis of lipid linked oligosaccharide precursor and proper N-linked glycosylation. De novo variants in ALG13 underlie a form of early infantile epileptic encephalopathy known as EIEE36, but given its essential role in g

Two-photon excitation laser induced fluorescence (2p-LIF) is used here for imaging through an optically dense spray system. The main advantage of the approach is that a low level of unwanted fluorescence signal originating from multiple-light scattering is generated. This leads to high visibility and image contrast even through scattering media, thus providing faithful descriptions of the imaged f

Existing researches on two-row film cooling mainly focused on double-jet film cooling. However, researches on the effects by combining different kinds of hole shapes on film cooling performance are quite limited. In order to improve the film cooling effectiveness, the three-dimensional numerical method is utilized to investigate the effects of a novel structure composed of two-row holes with diffe

Currently, policy makers in Sweden are considering updating building regulations with respect to daylight provision. Given this context, the present paper aims to provide insight on the level of compliance of residential spaces when tested against five daylight performance criteria. These included the criterion currently in force in Sweden, the two performance criteria set by European Standard EN1

Purpose: To meet the rising global needs, the humanitarian community has signed off on making a strategic change toward more localisation, which commonly refers to the empowerment of national and local actors in humanitarian assistance. However, to this date, actual initiatives for localisation are rare. To enhance understanding of the phenomenon, the authors explore localisation of logistics prep

Introduction: Social participation can have a positive impact on health; however, physical challenges can be hindrances. During a preventive home visit a health professional (visitor) assesses different aspects of physical, mental and social health. However, there might be a challenge for the visitor to discover the interrelationship between physical factors that hinder social participation. There

Attachment theory and research are drawn upon in many applied settings, including family courts, but misunderstandings are widespread and sometimes result in misapplications. The aim of this consensus statement is, therefore, to enhance understanding, counter misinformation, and steer family-court utilisation of attachment theory in a supportive, evidence-based direction, especially with regard to

Systems mixing Boolean logic and arithmetic have been a long-standing challenge for verification tools such as SAT-based bit-vector solvers. Though SAT solvers can be highly efficient for Boolean reasoning, they scale poorly once multiplication is involved. Algebraic methods using Gröbner basis reduction have recently been used to efficiently verify multiplier circuits in isolation, but generally

In the present work, the laminar burning velocities of the NH3+N2O+air flames were measured using the heat flux method at 1 atm and 298 K, with varied equivalence ratios and N2O mixing ratios. For the mixing ratio N2O/(N2O+air) = 0.5, a full range of equivalence ratios was covered. Moreover, at three equivalence ratios an extended range of mixing ratios was investigated. The laminar burning veloci

Lignin, the world's most abundant biopolymer with high aromaticity, has huge potential as a renewable feedstock replacing petroleum for the production of chemicals, fuels and functional materials. The enhanced utilization of lignin would improve the economic viability of existing pulp and paper mills, as well as lignocellulosic biorefineries, where lignin is highly available, but mostly incinerate

A new setup for burning velocity measurements of liquid fuels at elevated pressures using the Heat Flux method has been constructed. The burner design has been improved comparing to previous studies in this and other laboratories. Laminar burning velocities were determined experimentally for ethanol+air and methanol+air mixtures over a range of conditions including equivalence ratio (0.8 to 1.3),

Hovering insects are divided into two categories: ‘normal’ hoverers that move the wing symmetrically in a horizontal stroke plane, and those with an inclined stroke plane. Normal hoverers have been suggested to support their weight during both downstroke and upstroke, shedding vortex rings each half-stroke. Insects with an inclined stroke plane should, according to theory, produce flight forces on

Purpose: The aim of this planned study is to evaluate the ability of a cranial microwave scanner in conjunction with nine brain biomarkers (Aβ40, Aβ42, GFAP, H-FABP, S100B, NF-L, NSE, UCH-L1 and IL-10) to detect and rule out traumatic intracranial hemorrhage in an emergency department setting. Traumatic brain injury is a world-wide topic of interest for researchers and clinicians. It affects 2% of

Objective: The aim was systematically to identify and evaluate factors related to fatigue in individuals with hip and/or knee OA. Methods: A systematic literature search was conducted using AMED, CINAHL, MEDLINE, ProQuest and Web of Science Core Collections databases. Inclusion criteria comprised cross-sectional, case-control or longitudinal studies on patients with a diagnosis of hip and/or knee

Background: Urinary tract infections (UTIs) affect around 20% of the male population in their lifetime. The incidence of UTIs in men in the community is 0.9–2.4 cases per 1000 aged <55 years and 7.7 per 1000 aged ≥85 years. Aim: To evaluate the outcomes of randomised controlled trials (RCTs) comparing the effectiveness of different antimicrobial treatments and durations for uncomplicated UTIs in a