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Given the rise of new startups and the challenges amplified by events like the Covid-19, it is critical to address the notion of the Entrepreneurial Ecosystem which, in turn, facilitates the development of new ventures. One of the actors within this ecosystem is startup accelerators, which provide networking opportunities, financial and mentoring assistance to new ventures. Previous research on ac
We have estimated free energies for the binding of eight carboxylate ligands to two variants of the octa-acid deep-cavity host in the SAMPL6 blind-test challenge (with or without endo methyl groups on the four upper-rim benzoate groups, OAM and OAH, respectively). We employed free-energy perturbation (FEP) for relative binding energies at the molecular mechanics (MM) and the combined quantum mecha
Numerous protein biomarkers have been analyzed to improve prognostication in non-small cell lung cancer, but have not yet demonstrated sufficient value to be introduced into clinical practice. Here, we aimed to develop and validate a prognostic model for surgically resected non-small cell lung cancer. A biomarker panel was selected based on (1) prognostic association in published literature, (2) p
Aims: Abdominal aortic aneurysm is a life-threatening condition due to the risk of aneurysm growth and rupture. There are no approved diagnostic or prognostic biomarkers for abdominal aortic aneurysm. We aimed to identify diagnostic and prognostic biomarkers for abdominal aortic aneurysm and to investigate their relationship with abdominal aortic aneurysm diameter and growth. Methods: In this case
In England saltmarshes account for less than 0.5% of the land area; however they have a very high biodiversity value and provide significant economic and social services. Climate change, continuous coastal urbanisation and port development are serious concerns for coastal protection planners, city councils and state government agencies interested in balancing the social, economic and environmental
Introduction: Radiographic progression-free survival (rPFS) by Prostate Cancer Working Group (PCWG) criteria is a radiographic endpoint. The automated bone scan index (aBSI) quantifies osseous disease burden on bone scintigraphy as a percentage of total skeletal weight. Using the aBSI, we sought to quantify increase in tumor burden represented by PCWG progression criteria, and to determine the int
Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comp
Background: Since its discovery in 2007, the importance of the human gut bacterium Prevotella copri (P. copri) has been widely recognized with its links to diet and health status and potential as next generation probiotic. Therefore, precise, convenient and cost-effective diagnostic tools for the detection and quantification of P. copri from clinical and environmental samples are needed. Results:
Departure deviations from shunting yards impact the reliability of rail freight services and the punctuality of a railway network. Therefore, the statistical analysis of these deviations are necessary for improving the operation of trains in mixed-traffic networks. In our paper, we conduct a detailed statistical analysis of departure deviations considering individual shunting yards characteristics
Vegetation phenology obtained from time series of remote sensing data is relevant for a range of ecological applications. The freely available Sentinel-2 imagery at a 10 m spatial resolution with a ~ 5-day repeat cycle provides an opportunity to map vegetation phenology at an unprecedented fine spatial scale. To facilitate the production of a Europe-wide Copernicus Land Monitoring Sentinel-2 based
The current control strategy in the degassing system in a Gambro AK200S dialysis machine leads to a rather noisy flow upstream in the machine. This is where different concentrates are added to the dialysis fluid and as the control of this adding is rather slow the unsteady flow leads to an unsteady conductivity of the dialysis fluid, which makes it difficult to evaluate the effect of the dialysis
Children who witness violence against a parent falls victim to a form of mental abuse. The children often react in fear, anxiety and sadness. Children who witness violence are as much in need of help and support as those children who are themselves victims of violence. A person who is subjected to violence by their partners in Sweden have an opportunity to seek protection. With the help of social
After more than a century of colonial subjugation by the United States, Puerto Rico’s stunted development model has finally collapsed. As a result, the island is currently facing one of the worst economic crises in its history. Despite the United States’ continued affirmation of its political dominance over Puerto Rico, it has largely placed the blame for the crisis on Puerto Ricans themselves, ac
Lipases are the main fat digestive enzymes present in the digestive system of many animals, microorganisms and plants. Probiotic microorganisms that can possibly produce enzymes are of crucial importance since it can have an effect on human health. Two of the main probiotic strains are Lactobacillus rhamnosus and Biffidobacterium longum, in each there was a putative lipase encoded on the DNA and t
Yogurt is an ancient food, used for a better preservation of milk. Milk gets fermented by Streptococcus thermophilicus and Lactobacillus bulgaricus (lactic acid bacteria, LAB) which converts the lactose present in the milk to lactic acid. These probiotics support the microbial population balance of the gastrointestinal tract. Sweet potato, Ipomoea batatas, is an important security crop in developi
With the evolution of cartography from hand-drawn to digital maps, the task of icon placement has become increasingly complex. Nowadays there is a need to automate this process to produce high quality results in less time. This study aimed to optimize icon placement on city wayfinding maps, addressing challenges of placing icons in high-density areas and maintaining a strong association between ic
I denna kandidatuppsats undersöks rättsläget i Sverige gällande surrogatmoderskap med det huvudsakliga syftet att granska hur surrogatarrangemangets centralt berörda intressen återspeglas i befintlig lagstiftning och SOU 2016:11. Surrogatmoderskap är en form av assisterad befruktning och innebär att en kvinna genomgår graviditet och förlossning med avsikten att sedan lämna ifrån sig barnet. I svThis bachelor thesis examines the legal situation regarding surrogacy in Sweden, with the main purpose to review how the key interests of a surrogacy arrangement are reflected in current legislation and the public investigation SOU 2016:11. Surrogacy is a form of assisted fertilization and means that a woman goes through pregnancy and childbirth with the intention to hand over the child. Swedish
Ett av livets största beslut är beslutet om föräldraskap. Det är dessutom ett beslut som i slutändan görs av modern, eftersom det är hon som tar beslutet om abort. Härigenom uppstår en situation som inte är jämställd, vilket har orsakat en viss debatt den senaste tiden. Debatten gäller huruvida det bör finnas en rätt för fadern att göra en så kallad juridisk abort, alltså en möjlighet att avsäga sThe choice to become a parent is not an easy one to make, moreover it is today a choice more likely to be made by the mother. She has the opportunity of abortion, whereas the father can’t affect his becoming a parent after the moment of conception. This constitutes a situation of inequality between the sexes, which this year has caused a debate to arise in social media as well as in news papers. I
With increased demand and high prices for minerals and metals in recent years, many resource rich developing countries see mining sector as vital to develop their economies. Colombia is one of these nations. Non-renewable natural resource wealth is seen as an opportunity to obtain economic benefits that can be transformed into increased wellbeing for citizens. However, mining often involves a high
