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Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin
Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal
Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by
Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac
Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,
21 May 2026 14:30 to 15:30 | Other Do you have questions about the text and references for your thesis? Get help from our librarians and a language and study consultant via Zoom. During a one-hour session, we are available (with access to breakout rooms in Zoom) to answer any questions related to your thesis writing.Ask questions about:reference management (the reference list and in text reference
https://www.science-library.lu.se/calendar/thesis-writing-qa-7 - 2026-05-19
28 May 2026 14:30 to 15:30 | Other Do you have questions about the text and references for your thesis? Get help from our librarians and a language and study consultant via Zoom. During a one-hour session, we are available (with access to breakout rooms in Zoom) to answer any questions related to your thesis writing.Ask questions about:reference management (the reference list and in text reference
https://www.science-library.lu.se/calendar/thesis-writing-qa-8 - 2026-05-19
Utkast 2012-02-14 2012-02-22 Arende // Dnr LUNDS U N I V E R S I T E T Centrum for teologi och rel igionsvetenskap Arbets- och delegationsordning vid Centrum for teologi och religionsvetenskap (CTR) EnkgtArbetsordningforLunds universitet (2011-11-11, dnr LS 2010/625) ska en institution "ledas av en institutionsstyrelse som, inom de ramar som fakultetsstyrelsen beslutar, har ett samlat ansvar for u
https://www.ctr.lu.se/fileadmin/user_upload/ctr/pdf/policy/Arbets-och_delegationsordning002.pdf - 2026-05-18
One of the most important travelers of the 18th century was Jakob JonasBjörnståhl. From a young age, he aspired to reach prominence in academiccircles. Greek, Latin, and various Middle Eastern languages were part ofhis studies from the outset, and he distinguished himself by his enthusiasm,thirst for knowledge, and ability to quickly master diverse subjects, alongwith his encyclopedic education. HOne of the most important travelers of the 18th century was Jakob Jonas Björnståhl. From a young age, he aspired to reach prominence in academic circles. Greek, Latin, and various Middle Eastern languages were part of his studies from the outset, and he distinguished himself by his enthusiasm, thirst for knowledge, and ability to quickly master diverse subjects, along with his encyclopedic educati
Spectral aerosol light absorption is an important parameter for the assessment of the radiation budget of the atmosphere. Although on-line measurement techniques for aerosol light absorption, such as the Aethalometer and the Particle Soot Absorption Photometer (PSAP), have been available for two decades, they are limited in accuracy and spectral resolution because of the need to deposit the aeroso
https://www.geriatrik.lu.se/geriatrics/education - 2026-05-19
BACKGROUND: Brief admission by self-referral, a novel crisis intervention designed to reduce suicide and self-harm in adults, was adopted for adolescents in paediatric psychiatry in Malmö, Sweden, in 2018. We aimed to investigate changes in utilisation of emergency psychiatric care.METHODS: We did an observational longitudinal cohort study in The University Hospital in Malmö, Sweden, which provide
Den här artikeln är över 5 år gammal, och informationen kan därför vara inaktuell. För att öka samverkan mellan turism- och upplevelsebranschen, utbildning och forskning har Institutionen för Service management och tjänstevetenskap årligen bjudit in aktörer och organisationer till branschmöte. I slutet av maj ägde årets möte rum och då var temat Kulinarisk turism. Ett ämne som är högst aktuellt i
https://www.ses.lu.se/artikel/kulinarisk-turism-i-fokus - 2026-05-19
