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MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

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FRAF21 Franska: Grundkurs i Frankrike Semestre d’automne 2025 Hitta (student)boende i Toulouse Trouver un logement (étudiant) à Toulouse Detta dokument är tänkt som ett stöd för de studenter från Lunds universitet som kommer att åka till Université de Toulouse Jean Jaurès för att läsa franska under höstterminen 2025. Dokumentet innehåller information om hemsidor och länkar som hjälper er att komma

https://www.sol.lu.se/fileadmin/user_upload/sol/aemnen/sektion3/Logement_%C3%A9tudiant_%C3%A0_Toulouse_HT2025.docx - 2026-05-09

Changing the game - The effects of a radical logo rebranding strategy on the consumer-brand relationship in football

Purpose: The purpose of this thesis is to provide an understanding of how consumer-brand relationships are affected by a radical rebranding strategy of a football club’s logo. This further leads the paper to contribute to the literature of consumer-brand relationships in the special context of football. Methodology: The interpretative nature of this research calls for a qualitative research appro

Automatic Landing without GPS

Sagem Défense et Sécurité (now Safran Electronics & Defense), a French space and defense company of the SAFRAN group, is working on the next generation of Unmanned Aerial System (UAS). This UAS features a fully automatic Unmanned Aerial Vehicle (UAV) equipped with a state-of-the-art navigation system. This navigation system relies mainly on a high-accuracy Inertial Measurement Unit (IMU) coupl

Highly efficient CO2 and propylene oxide co-polymerization using Zn glutarate/Zn-Cr double metal cyanide composite catalyst

A highly active zinc glutarate-double metal cyanide (DMC) composite catalyst (ZnGA/Zn-CrDMC) was designed for the carbon dioxide (CO2) and propylene oxide (PO) copolymerization reaction. The composite catalyst was synthesized in a rheological phase reaction and characterized using Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), and scanning electron microscopy (SE

Asymptotic Performance Analysis of Distributed Non-Bayesian Quickest Change Detection with Energy Harvesting Sensors

This paper focuses on the distributed non-Bayesian quickest change detection based on the Cumulative Sum (CUSUM) algorithm in an energy harvesting wireless sensor network (WSN), where the distributions before and after the change point are assumed to be known. Each sensor is powered by randomly available harvested energy from the surroundings. It samples the observation signal and computes the log

Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow

This study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples. This strategy involves using antibodies circulating in plasma to affinity-enrich antigenic proteins in biochemically fractionated pools of bacterial proteins, followed by their identification and quantification using mass spe

Intercomparison of C-14 Analysis of Carbonaceous Aerosols: Exercise 2009

Radiocarbon analysis of the carbonaceous aerosol allows an apportionment of fossil and non-fossil sources of airborne particulate matter (PM). A chemical separation of total carbon (TC) into its subfractions organic carbon (OC) and elemental carbon (EC) refines this powerful technique, as OC and EC originate from different sources and undergo different processes in the atmosphere. Although C-14 an

High Affinity Antibodies to Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Malaria

Background: Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown. Methodology/Principal Findings: In this study, surface plasmon resonance technology was used to evaluate the affinity (measured as kd) of naturally acquired antibodies to the Plasmodium falciparum antigens MSP2 and AMA1. Antibodies in serum samp

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro

Certain monoclonal antibodies (mAbs) to type II collagen (CII) induce arthritis in vivo after passive transfer and have adverse effects on chondrocyte cultures and inhibit self assembly of collagen fibrils in vitro. We have examined whether such mAbs have detrimental effects on pre-existing cartilage. Bovine cartilage explants were cultured over 21 days in the presence of two arthritogenic mAbs to

Artefacts

Museum Stobaeanum included a collection of artefacts, originally labeled ”artificialia”. It consisted primarily of ethnographic objects from Asia, North and South America, Russia, Siberia, Greenland and Lapland, but also Classical antiquities, Nordic antiques, curious European works of art, as well as scientific instruments and models. Museum Stobaeanum included a comparatively small collection of

https://www.historiskamuseet.lu.se/stobaeus-project/artefacts - 2026-05-09

Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe : A report from the Innovative Therapies for Children with Cancer (ITCC) consortium

Introduction: Data regarding real-world impact on cancer clinical research during COVID-19 are scarce. We analysed the impact of the COVID-19 pandemic on the conduct of paediatric cancer phase I–II trials in Europe through the experience of the Innovative Therapies for Children with Cancer (ITCC). Methods: A survey was sent to all ITCC-accredited early-phase clinical trial hospitals including ques

Combinatorial Methodology. Screening for affinity specific ligands to biological and artificial receptors.

Combinatorial screening methodology has been employed to select new affinity specific ligands to bilogical and artificial receptors. The screening methodology, in particular screening of combinatorial phage display peptide libraries against target molecules differing in function and shape, is focused upon. A linear combinatorial phage display hexapeptide library has been used to select novel pept