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Microsoft Word - Rapport spänningsformlerOrtotropt080519 Master’s Dissertation Structural Mechanics PER JOHAN GUSTAFSSON STRESS EQUATIONS FOR 2D LAP JOINTS WITH A COMPLIANT ELASTIC BOND LAYER Denna sida skall vara tom! Copyright © 2008 by Structural Mechanics, LTH, Sweden. Printed by KFS i Lund AB, Lund, Sweden, May 2008. For information, address: Division of Structural Mechanics, LTH, Lund Univer

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm7000/web7148.pdf - 2026-07-24

Hepatitis B virus (HBV) strains from anti-HBe positive patients often show specific mutations in the precore gene, the core promoter region, or both. The dynamics of seroconversion in relation to the appearance of these mutations has not been studied and compared between defined HBV genotypes. Samples from patients followed during seroconversion from HBeAg to anti-HBe were amplified by polymerase

Antibodies directed against a pathogenic microorganism may recognize either protective or non-protective epitopes. Because antibodies elicited by a vaccine must be directed against protective epitopes, it is essential to understand the molecular properties that distinguish the two types of epitope. Here we analyse this problem for the antiphagocytic M protein of Streptococcus pyogenes, using the o

Under the principle of freedom of contract, when two parties begin contract negotiations, they are under no obligation to actually arrive at an agreement and each one carries the risk for its own expenses and losses caused by the negotiations. However, even if the main rule says that each party bears the costs it might have incurred during the negotiations, if the parties do not reach an agreement

Adult education in Sweden is extensive, based on a long tradition and range from higher education to non-formal popular education. Swedish adult education is highly decentralised and autonomous. As a general principle, adult education is free of charge for the learners and financed by the public budget. The Swedish perspectives takes it’s starting point from the initiatives of OECD, the European C

Objectives: To evaluate costs, benefits, and cost effectiveness of tumour necrosis factor inhibitor treatment over one year in routine clinical practice. Materials and methods: At four rheumatology units in southern Sweden treatment of 160 consecutive patients with RA was started with either etanercept or infliximab. The economic analysis was based on 116 patients with complete data who received

In the pancreatic islets, pituitary adenylate cyclase-activating polypeptide (PACAP) is expressed in beta cells and autonomic nerve terminals; the majority of these nerve terminals are parasympathetic. PACAP binds to three types of G protein-coupled receptors (GPCRs): VPAC1 receptors, VPAC2 receptors, and PAC1 receptors. All these receptor types are expressed in pancreatic islets. PACAP stimulates

Abstract Top Background Members of the Peroxisome Proliferator Activated Receptor, PPAR, subfamily of nuclear receptors display complex opposing and overlapping functions and a wide range of pharmacological and molecular genetic tools have been used to dissect their specific functions. Non-agonist bound PPARδ has been shown to repress PPAR Response Element, PPRE, signalling and several lines of ev

Background: Change in albuminuria as a surrogate endpoint for progression of chronic kidney disease is strongly supported by biological plausibility, but empirical evidence to support its validity in epidemiological studies is lacking. We aimed to assess the consistency of the association between change in albuminuria and risk of end-stage kidney disease in a large individual participant-level met

Under de senaste åren har västeuropeiska bedömare uttryckt oro över utvecklingen i Ungern och Polen. En ny spricka mellan Väst- och Östeuropa har tagit form, vilket märktes till exempel i samband med valet till Europaparlamentet förra året. Inte minst uppfattas Ungerns premiärminister Viktor Orbán och Frankrikes president Emmanuel Macron som representanter för ett östligt, bakåtblickande respektiv

Virtual Clinical Trials (VCT) are an effective tool to evaluate the performance of novel imaging systems using computer simulations. VCT results depend on the selection of virtual patient populations. In the case of breast imaging, virtual patients should be matched to a desired clinical population in terms of selected anatomical or demographic descriptors. We are developing a virtual population o

Borrelia burgdorferi sensu lato is a tick-borne pathogen that causes Lyme disease. The characterization of membrane proteins from this and other pathogens may yield a better understanding of the mechanisms of infection and information useful for vaccine design. Characterization of the highly hydrophobic Borrelia outer membrane component P13 from a mutant (OspA- OspB- OspC- and OspD-) strain was un

Mycobacterium tuberculosis (Mtb) is principally a pulmonary pathogen infecting one-third of the world's population and causing two million deaths annually. The only approved tuberculosis vaccine today is the Mycobacterium bovis bacilli Calmette-Guérin (BCG). BCG vaccine is used as a benchmark to compare the immunogenicity of new vaccines, but not much is known about its mechanisms to induce protec

Although the involvement of the tumor suppressor gene p53 in normal hematopoiesis is uncertain, it can give rise to differentiation signals in leukemic cells. It is not clear, however, whether differentiation merely is a consequence of the ability of p53 to arrest cell proliferation or whether hitherto unknown molecular mechanisms are responsible for the p53-mediated differentiation. To further ex