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The cerebrospinal fluid (CSF) biomarkers amyloid-beta (A beta)(1-42), T-tau, and P-tau have good diagnostic accuracy for clinically diagnosed Alzheimer's disease (AD). However, in multi-center studies, the predictive values of the CSF biomarkers have been lower, possibly due to differences in procedures for lumbar puncture and CSF handling and storage, and to differences in patient populations, cl
This dissertation concerns the field of applied psychiatry and focuses on the problems that are associated with the care and treatment of adult patients with autism spectrum disorders. The conditions that are described are valid for Swedish psychiatry and cannot be directly generalized to conditions outside of the country.
We present new polynomial-time approximation schemes (PTAS) for several basic minimum-cost multi-connectivity problems in geometrical graphs. We focus on low connectivity requirements. Each of our schemes either signifi- cantly improves the previously known upper time-bound or is the first PTAS for the considered problem. We provide a randomized approximation scheme for finding a biconnected graph
This thesis is based on three scientific papers dealing with costs and financial risks associated with keeping stock. Reasonable cost parameters are important to implement an effective inventory control system, which in turn is one of the key activities in logistics management. All three papers consider a single-level inventory system. Single-period, multi-period as well as continuous review syste
Wireless access technologies such as UMTS with HSPA extensions, WiMAX, and Flash-OFDM and the convergence towards next generation heterogeneous networks enable the realization of always best connected scenarios. As the resulting heterogeneous networks become easier to access and more reliable to depend on, novel telemedicine services such as vehicular emergency applications emerge. Due to their li
Background: Working conditions substantially influence health, work ability and sick leave. Useful instruments to help clinicians pay attention to working conditions are lacking in primary care (PC). The aim of this study was to test the validity of a short "Blue flags" questionnaire, which focuses on work-related psychosocial risk factors and any potential need for contacts and/or actions at the
Context. Determination and calibration of the ages of stars, which heavily rely on stellar evolutionary models, are very challenging, while representing a crucial aspect in many astrophysical areas. Aims. We describe the methodologies that, taking advantage of Gaia-DR1 and the Gaia-ESO Survey data, enable the comparison of observed open star cluster sequences with stellar evolutionary models. The
Preclinical data suggest that chronic stress may cause cellular damage and mitochondrial dysfunction, potentially leading to the release of mitochondrial DNA (mtDNA) into the bloodstream. Major depressive disorder has been associated with an increased amount of mtDNA in leukocytes from saliva samples and blood; however, no previous studies have measured plasma levels of free-circulating mtDNA in a
OBJECTIVES: The aim of this study was to compare fully quantitative cardiovascular magnetic resonance (CMR) and positron emission tomography (PET) myocardial perfusion and myocardial perfusion reserve (MPR) measurements in patients with coronary artery disease (CAD).BACKGROUND: Absolute quantification of myocardial perfusion and MPR with PET have proven diagnostic and prognostic roles in patients
How is it that a group that self-identifies as “religious” and is associated with one of the most dramatic events in the United States during the 1980s could receive almost no attention from religious studies scholars? Furthermore, how is it that the court case in which said group was determined to not qualify as a “religion” has been discussed and challenged by legal scholars while being virtuall
During the last 130 years, a number of exhibitions have interpreted and shown the Danish West Indies. The exhibitions are generally characterized by two tendencies: A rather romantic view on the colonial past with a strong focus on trade and the maritime. 2017 marked the centennial for the transfer of the Danish West Indies from Denmark to the United States. ;ore importantly, perhaps, it also mark
BACKGROUND:In recent years, survival after lung transplantation has remained largely unchanged despite improvements in short-and intermediate-term survival, indicating the need to identify factors associated with recovery and long-term survival. Very little is known about how lung recipients recover after lung transplantation and whether such factors are related to symptom distress and well-being.
In Europe, Scandinavia holds the largest concentration of rock art (i.e. petroglyphs), created c. 5000–first century BC, many of them showing figurative and seemingly narrative representations. In this paper, we will discuss possible narratological approaches applied to these images. We might reasonably distinguish between three levels of pictorial narrativity: representations of (i) single eventsIn Europe, Scandinavia holds the largest concentration of rock art (i.e. petroglyphs), created c. 5000–first century bc, many of them showing figurative and seemingly narrative representations. In this paper, we will discuss possible narratological approaches applied to these images. We might reasonably distinguish between three levels of pictorial narrativity: representations of (i) single events
We present a FrameNet-based semantic role labeling system for Swedish text. As training data for the system, we used an annotated corpus that we produced by transferring FrameNet annotation from the English side to the Swedish side in a parallel corpus. In addition, we describe two frame element bracketing algorithms that are suitable when no robust constituent parsers are available. We evaluated
PURPOSE: The purpose of the present study was to compare retinal function between the perifoveal nasal and perifoveal temporal areas of diabetic eyes using multifocalERG (mfERG). METHODS: We included 36 eyes from 27 patients with diabetes (age 58 ± 14 years; duration of diabetes 13 ± 9 years; HbA(1c) 7.1 ± 1.8%) and a control group with 18 eyes from 18 healthy subjects (age 57 ± 11 years). Retin
Scandinavia has historically been known for high levels of social justices. Universal and tax-funded social security and health systems, state pension and free basic as well as higher education became fundamental elements in creating more equal societies. Moreover, housing sectors based on use value rather than exchange value have historically been key to the development of Scandinavian welfare st
Vid strålbehandling används olika typer av strålning beroende på vad man ska behandla. Mätningarna i min undersökning gjordes på joniserande strålning med låg energi jämfört med den typ man vanligtvis förknippar med strålbehandling. Den sortens strålning som jag mätte på används främst vid behandling av åkommor som är relativt ytliga, till exempel hudcancer eller psoriasis. Läkarna ordinerar hur sAbsorbed dose was determined under reference conditions at four x-ray qualities; 30, 80, 120 and 200 kV using five different dosimetry protocols and codes of practice; IAEA TRS-398, AAPM, IPEMB, NCS and DIN. The dose determined by the IAEA protocol was chosen as reference. The dosimetry protocols use different formalisms for determining the absolute dose in a reference point. The IAEA and DIN prot
