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Natural killer (NK) cells represent the cytotoxic member within the innate lymphoid cell (ILC) family that are important against viral infections and cancer. Although the NK cell emergence from hematopoietic stem and progenitor cells through multiple intermediate stages and the underlying regulatory gene network has been extensively studied in mice, this process is not well characterized in humans
Digital breast tomosynthesis (DBT) has become a standard screening tool for breast cancer. However, its diagnostic performance is still limited compared to contrast-enhanced MRI, especially in women with dense breasts. Ultrafast dynamic contrast-enhanced (UF DCE) MRI and diffusion-weighted imaging (DWI) offer a shorter scanning time than conventional MRI and have shown promise in previous studies.
Clinical pathological diagnosis and prognosis for cancer is often confounded by spatial tissue heterogeneity. This study investigates the utility of entropy as a robust quantitative metric of spatial disorder within Fourier Transform Infrared (FTIR) chemical images of breast cancer tissue. The use of entropy is grounded in its capacity to encapsulate the complexities of pixel-wise spectral intensi
We present calculations on the formation of 258Rf in the reaction 50Ti+208Pb within the Langevin framework. The initital stage after contact of the colliding nuclei is dominated by a drift in the center-of-mass direction, while the subsequent process of forming a compound nucleus is diffusion dominated. The probability for the composite system to diffuse over the inner saddle is obtained by perfor
Since 1988, China's influence in Myanmar, both on a political and financial scale, has been relevant. Following the democratic bend that occurred in former Burma in 2011 and the ensuing opening to global markets, Beijing has partially lost its long-held privileges in the country. In order to maintain a solid geo-economic supremacy in Naypyitaw's internal affairs, since 2006, China has embarked upo
Inconel 718 is one type of nickel-based alloy used for a large range of applications, including gas turbines and aeroengines components. Although mechanical and thermodynamic properties of this material have been deeply studied in the past years, a method able to investigate local properties of the thin white layer formed on the alloy surface after machining remains challenging. Here, a 90 nm X-ra
IMPORTANCE: Behavior therapy is a recommended intervention for Tourette syndrome (TS) and chronic tic disorder (CTD), but availability is limited and long-term effects are uncertain.OBJECTIVE: To investigate the long-term efficacy and cost-effectiveness of therapist-supported, internet-delivered exposure and response prevention (ERP) vs psychoeducation for youths with TS or CTD.DESIGN, SETTING, AN
Objective: Powered mobility offers young children the opportunity to explore their world, develop awareness of their environment, and actively participate in play and daily activities. It enables children with severe disabilities to experience equity and equality by increasing their mobility. Powered mobility devices not only provide means for movement but also enhance children's understanding of
In this study, soil cores (0–20 cm) were collected at 45 sites located within a 30-km radius zone around the Belarusian nuclear power plant (BelNPP) in 2019 before its commissioning. Activity of gamma-emitting radionuclides was measured in the samples using HPGe detectors. The study revealed low levels of 137Cs in the soil: the weighted average dry weight (d.w.) activity concentration (ACw) varied
Popular Abstract in Swedish I en alltmer konkurrenskraftig omvärld är det av störst vikt att i ett högkostnadsland som Sverige att innovera och utveckla produkter så effektivt som möjligt. För att uppnå dessa mål finns det klara indikationer på att våra nuvarande produktutvecklings- och konstruktionstillvägagångssätt saknar väsentliga egenskaper för att uppnå önskvärd effektivitet. Den frekvent mIn an industrial context when the product development cycles are shortened and constraints on technical innovations are high, it is very important to provide a very efficient and effective engineering design activity. In the current engineering design literature, most methodologies are by and large based on the so-called systematic engineering design approach. This approach is characterized by an
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Information technology is a vital driver in today’s business environment. Recent developments of IT have facilitated for the relatively easy creation of markets on the Internet, so called B2B-marketplaces. However, judging from the survival rate of B2B-marketplaces (5 to 10 per cent), it seems like B2B-marketplaces are doing something wrong. This paper scrutinises several theoretical frameworks re
A novel photodynamic therapy system based on interstitial illumination using multiple fibres is under development. The aim with this system is to enable treatment of large tumour volumes and also to utilise real-time measurements to allow on-line dosimetry. Important dosimetric parameters to measure are light fluence rate, sensitizer fluorescence intensity and local blood oxygenation. A constructi
