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The tissue distribution and prognostic relevance of subtype-specific proteins (ASCL1, NEUROD1, POU2F3, YAP1) present an evolving area of research in small-cell lung cancer (SCLC). The expression of subtype-specific transcription factors and P53 and RB1 proteins were measured by immunohistochemistry (IHC) in 386 surgically resected SCLC samples. Correlations between subtype-specific proteins and in
Background and purpose — Information on outcomes after some modern total ankle replacement (TAR) designs is scarce. We therefore examined outcomes after trabecular metal (TM) TAR in Sweden by use of data from the national registry. Patients and methods — On December 31, 2020, 239 primary TM TARs had been reported to the Swedish Ankle Registry. We analyzed prosthesis survival probability, using exc
A basic theoretical model that describes the effects of flow in and out of the imaging plane in nuclear magnetic resonance (NMR) images, obtained with the standard pulse sequences single spin echo, multiple spin echo, and inversion recovery, is presented. Theoretically calculated signal values are compared with experimental results obtained from single-slice images of a flow phantom for variable f
The vapor–liquid–solid (VLS) mechanism is probably the most versatile method to fabricate semiconductor nanowires and several investigations assume a compositionally homogeneous catalyst particle. In this investigation we address the compositional homogeneity of the catalyst particle during growth of nanowires. Using diffusion calculations, we show that the particle is indeed homogeneous during VL
From the beginning Parajett was a printing company which has developed into a graphical IT company. Today Parajett delivers complete communication solutions to their customers. The customers demand more flexible solutions and this generates more work in the programming department. High postage cost, small edition and poor security are some of Parajett’s problems. To solve these problems Parajet wo
A transition probability is essentially a likelihood of ’something random’ transitioning from one state of being to another. Though, more formally, for all intents and purposes, the ’something random’ is a sequence of random events, which is a stochastic process. There are many stochastic processes that are valuable to understand. Examples can be found in a multitude of topics, from finance to biol
Föreliggande uppsats utreder förändringen från den 26 mars 2021 avseende den bredare tillämpningen av artikel 22 koncentrationsförordningen och undersöker de osäkerhetsmoment som därigenom uppstår för parter i företagsförvärv. Förändringen innebär ett tydligt avsteg från den Europeiska kommissionens väletablerade praxis i tillämpningen av bestämmelsen. Denna kursändring får som konsekvens att kritThe present thesis examines the changes from the 26th of March 2021 regarding the wider application of article 22 of the EC Merger Regulation, and examines the uncer-tainties that thereby arise for parties in certain mergers and acquisitions (M&A). The change constitutes a clear parting from the European Commission’s own, well-estab-lished practice regarding the application of the provision. T
Collecting and storing data is easier and more common than ever before. A lot of this data is personal data, which is problematic to store and use both for ethical reasons and because of legislations. In some scenarios the personal information in the data is not interesting or relevant for the given task but it is still collected and stored as a byproduct of the data collection. In these scenarios
Amelogenin is a major constituent of enamel matrix protein that is responsible for the development of tooth enamel. Due to its self-assembly and physicochemical properties, amelogenin has been widely used as one of the natural biomaterials. Amelogenin, along with the other enamel matrix proteins have been known for its regenerative properties. The purpose of this project is to evaluate the enginee
The purpose of this work was to contribute to the creation of a prototype of a new type of robot called Agile Parallel Kinematic Manipulator or AgilePKM for short. Designing, building and controlling a new type of robot is a task which goes beyond the scope of any master thesis project, but there are subtasks which are more suitable to handle within the available time frame. A principle design wil
Introduction: The main purpose of this study was to extract global values of oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) in healthy volunteers, using magnetic resonance imaging (MRI) phase maps. The repeatability of the method was evaluated, and the age dependences of OEF and CMRO2 were analyzed. Material and methods: Phase data were acquired using a 3T MRI scann
This essay mean to describe treatment in foster care in a special method called Multidimensional Treatment Foster Care. My purpose is to study the cost and consequences for break down in family placement through to MTFC-method with starting point in one particularly case. The MTFC-method treats adolescents with chronic delinquency and antisocial behaviour. It’s an alternative to residential treatm
Syftet med förevarande uppsats är att belysa den sakrättsliga problematiken kring lösöreköp genom att undersöka huruvida avtalsprincipen är förenad med tillräckligt stora fördelar för att ersätta den nu gällande traditionsprincipen. Traditionsprincipen har tillämpats i svensk rätt sedan 1800-talet. Dessförinnan erhöll en köpare skydd mot säljarens borgenärer genom köpeavtalet, i enlighet med avtaThe purpose of this essay is to throw light upon the complexity of the branch of law as regards the Swedish law of property and inquire whether the advantages of the doctrine of consensus exceed the benefits of maintaining the existing doctrine of traditio. The doctrine of traditio has existed in Swedish law since the 19th century. Before that, the buyer obtained protection against the seller’s cr
AimsOrthostatic hypotension (OH) is an important differential diagnosis in unexplained syncope. Neurogenic OH (nOH) has been postulated to differ from non-neurogenic OH (non-nOH), yet pathophysiological differences are largely unexplored. We aimed to investigate aetiology and tilt table test (TTT)-induced haemodynamic responses in symptomatic OH patients.Methods and resultsWe performed a retrospec
The higher education system has since the 2000s changed fundamentally in Finland, Norway, and Sweden. One reason behind this is so-called managerialism as a part of NPM, which means a shift towards more managerial forms of leadership, business-oriented aspects, and neoliberal university policies. Managerialism in all the Nordic countries conflicts with decades of collegial institutional tradition.
Background: Emerging evidence suggests that artificial intelligence (AI) can increase cancer detection in mammography screening while reducing screen-reading workload, but further understanding of the clinical impact is needed. Methods: In this randomised, controlled, parallel-group, non-inferiority, single-blinded, screening-accuracy study, done within the Swedish national screening programme, wo
