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Popular Abstract in Swedish Nollvisionen antagen av Sveriges riksdag fastlägger att ingen skall behöva dödas eller skadas svårt i trafiken i Sverige. Införande av detta begrepp förskjuter fokus från trafikolyckorna till konsekvenserna av trafikolyckorna och härmed skapas förutsättningar för ett paradigmskifte i trafiksäkerhetsarbetet. För att åstadkomma önskade förändringar är det nödvändigt och bThe over-arching objectives of this thesis were to formulate a method to describe the consequences of traffic casualties, and to explain the influence of different traffic engineering factors on these consequences for society and individuals over time. A more detailed objective was to examine whether available short-term indicators can be used to predict consequences in a long-term perspective. Ot

We investigate vascular changes during Photodynamic therapy (PDT) of skin tumors using optical Doppler tomography (ODT). The effect of vascular shut down on tumor destruction is currently not known, and to optimize treatment it is relevant to investigate this issue further. Optical Doppler tomography is capable of measuring blood flow in biological tissue down to 1-2 mm with sub-mm/s velocity sens

Deterministic Lateral Displacement (DLD) devices have been used to separate particles based on size [1] and shape [2]. Here we show how DLD devices can also be used to separate particles based on their ability to deform under shear forces. Varying experimental conditions allows us to vary the relative contributions of size, morphology and deformability. The ability to distinguish between cells bas

High-elevation hydropower units in California might be sensitive to climate warming since they have been designed to take advantage of snowmelt and have low built-in storage capacities. Snowmelt is expected to shift to earlier in the year and the system might not be able to store sufficient water for release in high-electricity-demanding periods. Previous studies have tried to explore the climate

This chapter examines the evolution of REDD+ governance and identifies policy options to increase synergies among REDD+, the sustainable management of forests and biodiversity conservation. REDD+ emerged at the international level as a point of convergemnce acorss the 'institutional complexes' of forests, climate and biodiversity. This convergence attracted the engagement of a wide range of instit

This paper examines whether or not specific forms of adaptation governance that involve city administrations and citizens can help (or hinder) creating a foundation for more sustainable climate adaptation and transformation. Based on the analysis of recurring patterns of social adaptation dilemmas (caused by the interdependencies between adaptation providers and beneficiaries), associated actor co

Kraven på historisk rättvisa har intensifierats under de senaste decennierna. Sanningskommissioner, officiella ursäkter och ekonomiska ersättningar är nu vanliga sätt att bemöta människors vittnesmål om oförrätter i det förflutna. Tidigare forskning har fokuserat på uppgörelser med krig och kolonialism. I denna avhandling studeras gottgörelse för kränkningar i samband med sociala interventioner.I In 1999 the Swedish Parliament decided to provide economic compensation to victims of involuntary sterilization, and in 2012 a similar law was enacted to redress neglect and abuse in foster homes and orphanages. This study explores the dilemmas that arise with reparations for past injustices, focusing on the process leading up to the reparation laws. Four themes are investigated: [1] state redress

Oligodendrocytes are part of the glial cells located in the central nervous system, capable of providing trophic support to neurons and ensheathing their axons. These cells can become dysfunctional under pathologic condition. Rodent and human pluripotent stem cells are inexhaustible sources for producing oligodendrocytes that can be used for disease modeling and cell replacement therapy studies. T

Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease with no known single predisposing genetic factor shown in all cases. Recently, a single nucleotide polymorphism (SNP) T393C in the GNAS1 gene has been reported to have a clinical impact on CLL progression and overall survival. In order to further investigate the T393C SNP in CLL, we have genotyped 279 CLL cases and correlated

Distinct morphologic and clinical features associated with specific chromosomal abnormalities have been described in subgroups of myelodysplastic syndromes (MDS), which often are losses or gains and only rarely translocations. Among 103 consecutive MDS patients diagnosed and karyotyped at the Albert-Ludwigs University of Freiburg (ALU) between 1993 and 1999, two chronic myelomonocytic leukemias (C

Mineralkvävegödsel är en av förutsättningarna för de höga skördenivåer som uppnåtts i det industrialiserade, moderna jordbruket. I Sverige finns idag ingen inhemsk produktion av mineralkvävegödsel, utan hela efterfrågan tillgodoses med import från utlandet. Produktionen är idag baserad på fossila resurser, vilka används både som råvara för produktionen och som energi för att driva processerna. Vi Mineral nitrogen fertilizer is one of the main reasons for the high yields in modern, industrial agriculture. There is currently no production of mineral nitrogen fertilizer in Sweden – the entire demand is met by imports from abroad. Global production is at present based on fossil resources, which are used both as raw materials for the production and as energy to fuel the process. We are thus dep

Life oil earth was formed during billions of years, exposed to, and shaped by the original physical forces such as gravitation, cosmic irradiation, atmospheric electric fields and the terrestrial magnetism. The Schumann resonances at 7.4 Hz are all example of oscillations possibly important for life.(1)) The existing organisms are created to function in harmony with these forces. However, in the l

The international development community is transitioning from the era of the Millennium Development Goals (MDGs), ending in 2015, to the era of the Sustainable Development Goals (SDGs), which have a 2030 target. Global development assistance for health (DAH) increased substantially in the MDGs era, from US $10.8 billion in 2001 to $28.1 billion by 2012 (in 2010 US dollars), and it played a crucial

BACKGROUND: To analyze the potential effect of social inequality on pancreatic cancer risk in Western Europe, by reassessing the association within the European Prospective Investigation into Cancer and Nutrition (EPIC) Study, including a larger number of cases and an extended follow-up.METHODS: Data on highest education attained were gathered for 459,170 participants (70% women) from 10 European

Background: Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills.We

The X-ray scanning microscope PtyNAMi at beamline P06 of PETRA III at DESY in Hamburg, Germany, is designed for high-spatial-resolution 3D imaging with high sensitivity. Besides optimizing the coherent ux density on the sample and the precision mechanics of the scanner, special care has been taken to reduce background signals on the detector. The optical path behind the sample is evacuated up unti