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Background and purpose — Patients having a total knee arthroplasty (TKA) after a previous high tibial osteotomy (HTO) constitute a minor group among those undergoing primary TKA for knee osteoarthritis (OA). There have been few reports on whether such patients differ pre- and postoperatively from those who undergo TKA as the first measure. We evaluated patient characteristics, knee-related pain, f
Within the insect order Lepidoptera (moths and butterflies), the so-called nonditrysian superfamilies are mostly species-poor but highly divergent, offering numerous synapomorphies and strong morphological evidence for deep divergences. Uncertainties remain, however, and tests of the widely accepted morphological framework using other evidence are desirable. The goal of this paper is to test previ
It is our impression that Gordon Pask’s writings cover fundamentals for large parts of the widely expanding fields of Cybernetics and Systems Theory. Thereby, and by his lecturing activities, he has become a unique figure in maintaining a kind of unity of the field of Cybernetics, well in accord with Wiener’s view (“control and communication in the animal and the machine”; cf[26]). And that, with
Objectives: There is growing concern regarding waiting times in health care as a mechanism to improve fairness in health services. This essay addresses the issue by evaluating fairness defined by justice theories. Based on this discussion, the essay then investigates whether actual waiting times are consistent with ethical principles. Theory: The theories of justice discussed are utilitarianism, e
The aim of this thesis is to understand how migrants perceive their opportunities to access health care, and how underlying factors result in barriers impacting their access to health care and ability to safeguard their health. It does so by answering the research question: How do Venezuelan migrants in Medellín perceive their access to health care? To fulfil the aim and answer the research questi
Developing an e-government in a state has become a new trend in the world of political reform. However, e-government itself as a way of public service digitalization does not incline that political regime of the state will be democratic and inclusive. When e-government has been usually researched in the democratic setting, question marks remain of how it works in the non-democratic one. This paper
In connection to the Covid-19 pandemic, the global economy suffered significant damage regarding supply chains and the flow of free, open markets. In the aftermath of these struggles, both researchers and the public are debating a potential shift towards moving production sites closer to the market. This development, in combination with the ongoing establishment of larger production sites in Norrl
The aim of this study was to examine social service workers’ experiences of the relationship between their work-sphere and their private-sphere, as well as understand how they discuss this relationship. We conducted eight qualitative semi-structured interviews with social service workers who work with child welfare, in five different social services in Skåne. The material we obtained from the inte
Dataharmonisering är en förutsättning för smarta städer, för ett mer effektivt informationsflöde i samhällsbyggnadsprocessen och för många andra tillämpningar i en stadsmiljö. Vid ett bästa tänkbart scenario kommer dataharmonisering att resultera i ett digitalt informationsflöde som inkluderar information från ett objekts hela livscykel, till exempel för byggnader, vägar och tunnlar. Alla aktörer Data harmonisation is a prerequisite for smart cities, for a more efficient information flow in the planning and building process and for many applications in the urban environment. Ideally, data harmonisation will result in a digital information flow that include information from the whole lifecycle of a feature, for example for buildings, roads and tunnels. All actors and applications involved i
Prostate-specific antigen (PSA) has been the main drive for early detection of prostate cancer (PCa), including in population-based screening as in the European Randomised Study for Screening of Prostate Cancer (ERSPC). The specificity of PSA to indicate men with biopsy detectable prostate cancer can be improved by adding information obtained by new biomarkers, such as PSA isoforms. This improveme
Gene fusions have been discussed in the scientific literature since they were first detected in cancer cells in the early 1980s. There is currently no standardized way to denote the genes involved in fusions, but in the majority of publications the gene symbols in question are listed either separated by a hyphen (-) or by a forward slash (/). Both types of designation suffer from important shortco
Post partum depression är ett omfattande folkhälsoproblem som utlandsfödda mödrar löper ökad risk att drabbas av. Rutinmässig screening av alla nyblivna mödrar för post partum depression har implementerats i många länder för att öka identifikationen, men tidigare forskning indikerar att hälso- och sjukvårdspersonal upplever screening av utlandsfödda mödrar som en svår arbetsuppgift. Det övergripanPostpartum depression is a major public health problem, which immigrant mothers are at particular risk of being affected by. Routine screening is implemented by many countries to increase identification, but research suggests that health care professionals experience screening of immigrant mothers as challenging. The overall aim of this thesis was therefore to develop an evidence-based educational
Polyphenolic compounds in bark are resources of great interest to produce renewable chemicals and several different technologies are available or under early development for the extraction of these types of compounds. Since critical environmental effects of a product are often set during the design phase, it is important to use life cycle assessment (LCA) to identify the steps resulting in the lar
This paper describes a strategy for a general search used by the ATLAS Collaboration to find potential indications of new physics. Events are classified according to their final state into many event classes. For each event class an automated search algorithm tests whether the data are compatible with the Monte Carlo simulated expectation in several distributions sensitive to the effects of new ph
During the past decade, scholars have produced a vast amount of research using linked historical individual-level data, shaping and changing our understanding of the past. This linked data revolution has been powered by methodological and computational advances, partly focused on supervised machine-learning methods that rely on training data. The importance of obtaining high-quality training data
Background: Newborn infants undergoing therapeutic hypothermia (TH) are exposed to multiple painful and stressful procedures. The aim of this systematic review was to assess benefits and harms of pharmacological and non-pharmacological interventions for the management of pain and sedation in newborn infants undergoing TH for hypoxic-ischemic encephalopathy. Methods: We included randomized and obse
The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research using various approaches including genetics, imaging, clinical and animal models has advanced our knowledge regarding NPDs, we still lack basic knowledge regarding the underlying pathophysiological mechanisms. Moreover
Despite the increasing recognition of the critical role that nature-based solutions (NBS) play in urban resilience, decision-makers in many cities across the Global South continue to prioritize grey infrastructure and engineered solutions. This prevailing approach may offer short-term economic advantages but ultimately falls short in ensuring the long-term sustainability and resilience of communit
