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Adequate heat balance is critical to human performance in the heat. If heat balance cannot be maintained, the core temperature increases and body water dehydration leads to exhaustion and limit the performance. Clothing heat transfer properties.. thermal insulation and water vapour resistance, modify heat exchange and may indirectly affect performance. Work in protective clothing quickly becomes e

This book shows that the intensity of use of energy and materials in OECD countries is diminishing over time despite falling metal and energy prices. Material demand is sometimes falling in absolute terms, but there are also a few examples of rapid growth. The supply of fossil fuels and minerals is being exhausted, in some cases at a rapid speed, but the question addressed here is whether the rat

In contrast to risk management studies on organisations that overtly deal with risk, this article explores organisational risk management in a context in which risk is more or less absent from managerial vocabulary or organisational communication. It presents a single case study of a Swedish public transportation authority in which managers actually attend to a multitude of risk matters through co

The genetic variance-covariance matrix (G) has long been considered to summarize the genetic constraints biasing evolution in its early stages, although in some instances, G can enhance divergence and facilitate adaptation. However, the effects of G on the response to selection might be of less importance than previously thought. In addition, it has been suggested that selection itself, under cert

Three potential filter materials, granular activated carbon, bone meal and iron fines, were evaluated for treatment of heavy metal contaminated landfill leachate. All materials could sorb some metals to a high extent; more than 90 % of some metals were removed. However, all filters suffered from the drawback of releasing unwanted substances. Geochemical modelling was used to elucidate sorption mec

The immunoglobulin D (IgD)-binding protein MID/Hag of the human respiratory pathogen Moraxella catarrhalis is an outer membrane protein of approximately 200kDa belonging to the autotransporter family. MID also functions as an adhesin and hemagglutinin. In the present paper, the ultrastructure of MID was mapped. Using a series of Escherichia coli transformants, the last 210 aa of the C-terminal reg

Adjuvant pelvic radiotherapy has the potential to eradicate micrometastases within the irradiated field but has not resulted in survival improvements in randomized studies. This illustrates the need for systemic therapy. Chemotherapy, mainly with anthracyclines, platinum compounds, and taxanes, renders high response rates although this unfortunately translates in only modest improvements in progre

“The Future is distributed: a vision of sustainable economies” is a collection of case studies on distributed economies, a concept describing sustainable alternatives to the existing business models. The authors of this publication are international Masters students of the Environmental Sciences, Policy and Management Programme at the International Institute for Industrial Environmental Economics

Introduction Human breast tumors are heterogeneous and consist of phenotypically diverse cells. Breast cancer cells with a CD44(+)/CD24(-) phenotype have been suggested to have tumor-initiating properties with stem cell-like and invasive features, although it is unclear whether their presence within a tumor has clinical implications. There is also a large heterogeneity between tumors, illustrated