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IntroductionLow serum selenium and altered tumour RNA expression of certain selenoproteins are associated with a poor breast cancer prognosis. Selenoprotein expression stringently depends on selenium availability, hence circulating selenium may interact with tumour selenoprotein expression. However, there is no matched analysis to date.MethodsThis study included 1453 patients with newly diagnosed

The first part of this study focuses on the effect of cone calorimeter test variables on polyurethane flexible foam properties such as ignitability, heat release rate, effective heat of combustion and mass loss. Three of the main commercial foam types were used, i.e. conventional slabstock foams, high‐resilience slabstock foams and all‐MDI (methylene diphenyldiisocyanate) moulded foams. A decrease

The first part of this study focused on the effect of cone calorimeter test variables on polyurethane flexible foam properties such as ignitability, heat release rate, effective heat of combustion and mass loss. Three of the main commercial foam types were used; viz. conventional slabstock foams, high resilience slabstock foams and all-MDI moulded foams. A decrease in heat flux (down to 40%) with

In fMRI studies with evoked activity, brain activity is detected by voxel-wise GLM tting, followed by statistical hypothesis testing. Statistical parametric mapping (SPM), one of the most popular classical methods, relies upon Gaussian smoothing to deal with the multiple-comparison correction. As an alternative, we have recently introduced a graph-based framework for fMRI brain activation mapping

Objective Comparison of provider performance is commonly used to inform health care decision-making. Little attention has been paid to how data presentations influence decisions. This study analyzes differences in suggested actions by decision-makers informed by league tables or funnel plots.Design Decision-makers were invited to a survey and randomized to compare hospital performance using either

Infant Acute Lymphoblastic Leukemia (ALL) driven by the KMT2A::AFF1 onco-fusion is an aggressive, poor prognosis disease with few co-operative mutations. The fusion originates in utero, yet the embryonic initiating steps of disease development remain poorly understood. Here, we present a novel murine KMT2A::AFF1 model, that provides key insights into KMT2A::AFF1 pre-leukemia, relevant to human dis

Nanowires have an ideal shape for high-resolution imaging, with a small cross-section for high resolution and a long length for strong absorption. However, since the absorption in nanowires is dominated by nanophotonic effects, it is unclear what resolution and efficiency such devices could offer. Here, we investigate the limits of spatial resolution and efficiency of nanowire-based direct detecto

The structure and dynamics of intrinsically disordered proteins (IDPs) are malleable to solution conditions. Considerable effort has been devoted to understanding the effects of molecular crowding on these properties. Polymer-based crowders, such as polyethylene glycol (PEG) and Ficoll®, are commonly used to simulate the intracellular environment by replicating the high concentration of macromolec

Phage collections are essential tools for discovering and dissecting bacterial anti-phage defense systems. Here, we report the isolation, characterization, and annotated genome sequences of five environmental Escherichia coli-infecting phages, obtained during the 2023 Fundamentals of Basic and Applied Phage Biology course at Lund University. The phages were isolated using a motile E. coli K-12 BW2

Star clusters stand at the crossroads between galaxies and single stars. Resolving the formation of star clusters in cosmological simulations represents an ambitious and challenging goal, since modelling their internal properties requires very high resolution. This paper is the third of a series within the SImulating the Environment where Globular clusters Emerged (SIEGE) project, where we conduct

The International Monetary Fund (IMF) is a highly influential financial international organization that will be vital for the success of the Sustainable Development Goals (SDGs). While the IMF has been criticized by civil society actors for its negative impact on sustainable development, it is now focusing on supporting the SDGs. This support is particularly relevant when it comes to ensuring the

Accountability is central for accelerating progress towards achieving the Sustainable Development Goals (SDGs). It means to hold powerful actors answerable for how they turn agreements into action. Governments, who hold the main responsibility for SDG implementation, can in the ideal case be held accountable by voters, parliaments, civil society, and the media, for how they address the SDGs. At th