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OBJECTIVE: To monitor serum concentrations of the aggrecan alanine-arginine-glycine-serine (ARGS) neoepitope in a clinical trial of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 inhibition as disease-modifying therapy of knee osteoarthritis, and to investigate relationships between reduction in ARGS and change in cartilage thickness, knee-related pain and function. DESITo monitor serum concentrations of the aggrecan alanine-arginine-glycine-serine (ARGS) neoepitope in a clinical trial of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 inhibition as disease-modifying therapy of knee osteoarthritis, and to investigate relationships between reduction in ARGS and change in cartilage thickness, knee-related pain and function.DesignROCCELLA t

Excited state dynamics of three iron(II) carbene complexes that serve as prototype Earth-abundant photosensitizers were investigated by ultrafast optical spectroscopy. Significant differences in the dynamics between the investigated complexes down to femtosecond time scales are used to characterize fundamental differences in the depopulation of triplet metal-to-ligand charge-transfer (3MLCT) excit

https://www.innovation.lu.se/en/sites/innovation.lu.se.en/files/lu-innovation_yib2019_webb.pdf - 2026-06-04

Eco Schools – Are They Really Better? Comparison of Environmental Knowledge, Attitude and Actions between Students in Environmentally Certified Schools and Traditional Schools in Iceland By Salome Hallfreðsdóttir salomehall@gmail.com Supervisor Dr. Kimberly Nicholas kimberly.nicholas@lucsus.lu.se A thesis submitted in partial fulfillment of the requirements of Lund University International Master’

https://www.lumes.lu.se/sites/lumes.lu.se/files/hallfredsdottir_thesis_2011.pdf - 2026-06-04

Analyses with Point Scheme Risk Analysis method for hospital wards and event tree analysis at several ward at homes for the aged in order to evaluate the agreement between the two methods.

The dissertation is about career in working life – not career solely in the sense of climbing upwards in the organizational hierarchy to management level, but career as the movement that individuals or groups make over time through working life. The focus is on social workers and their professional field. The overall aim is to describe and analyse social workers’ career patterns and careers at the

Abraham från Godegård – berättelsen om en originell människa och hans musik bygger på Peter Berrys mångåriga efterforskningar om folkskolläraren Abraham Hagholm (1811-1890). Hagholm var son till en fattig torpare i en avlägsen socken av Östergötland och drabbades i tidig ålder av förlamning. Hagholm övervann svårigheterna i sitt liv genom sin starka vilja och sitt livslånga engagemang i musik. Ida

Popular Abstract in Swedish Den globala landbaserade kolcykeln reglerar mängden växthusgaser i atmosfären. För närvarande tas varje år 25-30% av våra utsläpp upp av de landbaserade ekosystemen vilket är en viktig ekosystemtjänst som kanske inte kommer att bestå i längden. Upptagskapaciteten av både hav och landbaserade ekosystem tenderar att försvagas av global uppvärmning. Detta leder till att enThe global terrestrial carbon cycle plays a pivotal role in regulating the atmospheric composition of greenhouse gases. Currently it is responsible for removing 25-30% of our emissions every year, an important ecosystem service that may not persist in the long term. Global warming tends to decrease the CO2 sink capacity of the world’s oceans and ecosystems leading to a larger fraction of our emiss

Popular Abstract in Swedish Vattentransporten i växter är viktig för en mängd olika processer. De flesta fritidsodlare vet att vattentillgången påverkar växternas utveckling i stor utsträckning. För att solros ska kunna gro, växa, vända sig mot solen och bilda nya frön, behöver vatten flöda på ett kontrollerat sätt genom olika celltyper i växten. Växter transporterar vatten på olika sätt. Över lånPlant water channels are members of the very old Major Intrinsic Protein (MIP) family, with representatives in bacteria, fungi, animals, and plants. The genome of the model plant Arabidopsis thaliana contains 35 MIP genes. Based on protein sequence comparisons, the MIP family has been divided in four subfamilies: the PIP (Plasma membrane Intrinsic Protein), the TIP (Tonoplast Intrinsic Protein), t

Popular Abstract in SwedishUnder slutet av 1950-talet, ungefär samtidigt med tv:s etablering, innehade Sverige Europarekordet vad gäller antalet biografer. Folk gick på bio som aldrig förr. Biograferna att spela en mycket stor roll för film- och biografkulturens tillgänglighet och spridning. Den här boken handlar om att gå på bio. Genom att gå på bio lärde sig människor att se och uppleva film ochGoing to the Pictures The Cinema as a Meeting Place in the 1940s and 1950s Summary At the end of the 1950s, at roughly the same time as television became established, Sweden had the largest number of cinemas of any country in Europe. People went to the cinema in unprecedented numbers. In 1956 ticket sales in Swedish cinemas reached 80 million. There were palatial cinemas which offered people a f

The Helicobacter genus now consists of at least 26 species, with additional novel species in the process of being validated. Beyond the impact of H. pylori and human health, considerable research has focused on other Helicobacter species isolated from humans and animals and the associated natural diseases that range from subclinical inflammation to cancer in the gastrointestinal and hepatobiliary

Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. E140Q-Tr2C exhibits global conformational exchange on the microsecond time-scale. The populati

The doubly magic nucleus ¹⁰⁰Sn represents a crucial test for the nuclear shell model, which is a widely used model for a quantitative description of nuclei. Excited states in ¹⁰⁰Sn are experimentally not accessible with present day techniques, but it is possible to gain insight into its structure by studying the properties of excited states of neighboring nuclei. These nuclei

The tight junction protein claudin-4 has been reported to be overexpressed in advanced ovarian cancer. We investigated the prognostic significance of claudin-4 overexpression and whether claudin-4 expression could predict platinum response in primary ovarian carcinoma (OC). Claudin-4 expression was evaluated by immunohistochemistry in a tissue microarray of 140 OCs. Multivariable Cox-regression mo

Miljöbalkens övergripande mål är att uppnå hållbar utveckling enligt balkens portalparagraf. Begreppet består av tre element: ekologisk, ekonomisk samt social hållbarhet. Hållbar utveckling ska genomsyra tillämpningen av hela balken. För att hållbar utveckling ska förverkligas krävs att underliggande delmål beaktas. Inom ramen för det övergripande målet finns 16 miljökvalitetsmål fattade av riksdaThe main objective of the Environmental Code (miljöbalken) is to achieve sustainable development, according to the code’s initial paragraph. The objective of sustainable development consists of three pillars: ecological, economic and social sustainability. Sustainable development is supposed to permeate and influence the application of the entire Environmental Code. In order to achieve the goal of

Underexplored Gram (-) bacteria as a new source of natural products. Microorganisms produce an impressive array of structurally diverse and complex natural products with industrially-important properties. Microbial natural products therefore continue to be an important source of clinical drug candidates. While natural products from a few soil Gram (+) bacteria, together with their biosynthetic pa

Urban Sprawl is one of the challenges to urban development in many nations. Different aspects of the phenomenon have been researched with a view to providing solutions to myriad of ills attributed to it. For any meaningful intervention, however, assessment of development to ascertain sprawl is essential. Despite this, its quantification and monitoring in environment with paucity of data remains a