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Dynamic modelling of the forest ecosystem: Incorporation of the phosphorus cycle

Skogsekosystemet är ett av de viktigaste ekosystemen på jorden. Skogen förser oss med mycket som vi har nytta av, vilket numera ofta kallas ekosystemtjänster. Skogen reglerar och förser oss med många viktiga ekosystemtjänster, till exempel biodiversitet, skydd av mark och vatten, tillförsel av fiber, bränsle och andra skogsprodukter, klimatreglering samt sociokulturella värden och tjänster. ArealeThe forest ecosystem provides and regulates many important ecosystem services, such as soil and water protection, timber production, and climate regulation. It has been influenced by changes induced by humans, for example, our increasing demand for timber and bioenergy, the increase in nitrogen (N) deposition and CO2 concentrations due to industrialization, and climate change which has caused an i

COVID-19 vaccine effectiveness against severe disease from SARS-CoV-2 Omicron BA.1 and BA.2 subvariants - surveillance results from southern Sweden, December 2021 to March 2022

We compared vaccine effectiveness against severe COVID-19 between December 2021 and March 2022 when Omicron BA.1 and BA.2 were the dominating SARS-CoV-2 variants in Scania county, Sweden. Effectiveness remained above 80% after the transition from BA.1 to BA.2 among people with at least three vaccine doses but the point estimate decreased markedly to 54% among those with only two doses. Protection

Cultural ideals in the entrepreneurship industry

As both public and private organizations are spending resources on fostering entrepreneurship, we have witnessed the emergence of an entrepreneurship industry. Using the entrepreneurship industry in Sweden as a case and example, this chapter provides an explorative analysis the emergence, manifestations and consequences of cultural ideals within this industry. The analysis reveals how the entrepre

Counterintuitive Electrostatics upon Metal Ion Coordination to a Receptor with Two Homotopic Binding Sites

The consecutive binding of two potassium ions to a bis(18-crown-6) analogue of Tröger’s base (BCETB) in water was studied by isothermal titration calorimetry using four different salts, KCl, KI, KSCN, and K2SO4. A counterintuitive result was observed: the enthalpy change associated with the binding of the second ion is more negative than that of the first (ΔH°bind,2 < ΔH°bind,1). This remarkable f

The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor

Despite recent improvement in adjuvant therapies, triple-negative, and ER+ subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), a key upstream factor of PI3K/AKT, and the therapeutic effect of PIP5Kα inhibitor on subtypes of BC. The clinical importance of PIP5K1Despite recent improvement in adjuvant therapies, triple-negative, and ER+ subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), a key upstream factor of PI3K/AKT, and the therapeutic effect of PIP5Kα inhibitor on subtypes of BC. The clinical importance of PIP5K1

Investigating the prognostic value of mammographic breast density and mammographic tumor appearance in women with invasive breast cancer : The Malmö Diet and cancer study

Background: High breast density is a risk factor for breast cancer. However, whether density is a prognostic factor is debatable. Also, tumor appearances are related to tumor characteristics. Here we investigate the relationship between breast cancer-specific survival and mammographic breast density and mammographic tumor appearances. Methods: Women in the Malmö Diet and Cancer study with invasive

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer

Analysis of DNA methylation is a valuable tool to understand disease progression and is increasingly being used to create diagnostic and prognostic clinical biomarkers. While conversion of cytosine to 5-methylcytosine (5mC) commonly results in transcriptional repression, further conversion to 5-hydroxymethylcytosine (5hmC) is associated with transcriptional activation. Here we perform the first st

Deep Learning Algorithms for Cardiac Image Classification and Landmark Detection

Artificiell intelligens (AI) har under de senaste åren används framgångsrikt inom många olika områden. Ett område där dessa AI algoritmer ännu inte slagit igenom är sjukvården, där denna typ av automatisering utgör en potentiell lösning på de långa vårdköerna som finns idag. I denna rapport utvärderas den potential artificiell intelligens har för att lösa problem inom medicinsk bildanalys.With the increase in computational power, deep learning algorithms have become an active field of research over the last 7 years. These data-driven machine learning algorithms have produced good results in many applications, image analysis being one of them. Today, many image analysis tasks in the medical field are done manually, taking valuable time and effort from professionals. Automating some

Rätten att leva som andra - En rättsfallsanalys av HFD 2017 ref. 27 ur ett rättssäkerhetsperspektiv

Innan 1994 fanns ingen lagstadgad rätt till personlig assistans. Efter den s.k. Handikapputredningen år 1989 kom ett lagförslag som utmynnade i Lag (1993:387) om stöd och service till vissa funktionshindrade (LSS). Enligt denna lag skulle de funktionshindrade som hade krävande och omfattande hjälpbehov ha rätt till en personlig assistent. Försäkringskassan blev beslutsmyndighet för att avgöra huruBefore 1994 there was no legal right to a personal assistant in Sweden. After the so-called Handikapputredningen in year 1989, Lag (1993) om stöd och service till vissa funktionshindrade (LSS) was instituted.* According to this law, the disabled people who had exigent and extensive needs would have right to a personal assistant. The Swedish Social Insurance Agency (SSIA) became the agency responsi

To bee or not to bee - an evaluation of management strategies to promote pollinators in private gardens

Rädda bina! Planteringar och anlagda ängar; funkar de? I takt med att befolkningsmängden i världen ökar, växer våra städer, vilket leder till att naturliga habitat för växter och djur minskar. Vi människor förlitar oss på den naturliga miljön för att överleva. Exempelvis måste våra grödor pollineras. En viktig pollinationsgrupp är insekter. Bin, humlor, blomflugor och fjärilar är viktiga insektsUrbanisation has an increasingly negative effect on wild bees and other pollinating insects because it results in land-use change and habitat-loss, leading to population declines. We rely on ecosystem services that bees provide and must ensure their survival. Private gardens constitute a substantial part of green spaces in cities, making them important foraging habitats for pollinators. In 2018 Th