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A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes

Obesity and type 2 diabetes are causally related, yet there is considerable heterogeneity in the consequences of both conditions and the mechanisms of action are poorly defined. Here we show a genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects. We annotate and then compare association signals for these profiles across clinical an

Deep Learning Algorithms for Cardiac Image Classification and Landmark Detection

Artificiell intelligens (AI) har under de senaste åren används framgångsrikt inom många olika områden. Ett område där dessa AI algoritmer ännu inte slagit igenom är sjukvården, där denna typ av automatisering utgör en potentiell lösning på de långa vårdköerna som finns idag. I denna rapport utvärderas den potential artificiell intelligens har för att lösa problem inom medicinsk bildanalys.With the increase in computational power, deep learning algorithms have become an active field of research over the last 7 years. These data-driven machine learning algorithms have produced good results in many applications, image analysis being one of them. Today, many image analysis tasks in the medical field are done manually, taking valuable time and effort from professionals. Automating some

To bee or not to bee - an evaluation of management strategies to promote pollinators in private gardens

Rädda bina! Planteringar och anlagda ängar; funkar de? I takt med att befolkningsmängden i världen ökar, växer våra städer, vilket leder till att naturliga habitat för växter och djur minskar. Vi människor förlitar oss på den naturliga miljön för att överleva. Exempelvis måste våra grödor pollineras. En viktig pollinationsgrupp är insekter. Bin, humlor, blomflugor och fjärilar är viktiga insektsUrbanisation has an increasingly negative effect on wild bees and other pollinating insects because it results in land-use change and habitat-loss, leading to population declines. We rely on ecosystem services that bees provide and must ensure their survival. Private gardens constitute a substantial part of green spaces in cities, making them important foraging habitats for pollinators. In 2018 Th

Marockansk Arkitektur, traditionell och modern

This thesis is about traditional and modern architecture in Casablanca, Morocco. Morocco is located in north-western Africa and Casablanca is the country's largest city with a population of 3.3 million (2011). Morocco has a long history with many different rulers which have left its mark on the country's architecture. The old, traditional architecture of Casablanca is in the old medina, Me

Dynamic effluents : a political economy analysis of the water sector in Lebanon

After years of neglect, Lebanon is facing the consequences of a struggling water sector. Existing water networks are deficient; water supply continuity is low; most wastewater is discharged into rivers or the Mediterranean Sea without adequate treatment; and inter-agency coordination remains weak and fragmented. In 2000, the government together with international donor agencies initiated a reform

Becoming a Citizen:The Process of Leaving a Gang in Cape Town, South Africa

This study investigates the process of how eight people left competing informal institutions, in the form of gangs, to join substitutive informal institutions, which is more compatible with a democratic society, and in this way became ‘good citizens’. The research question is as follows: How do ex-gang members explain their change in lifestyle, from past involvement in gangs to the subsequent tran

A development of a tool to improve traceability between requirement and verification

In the development of a product or system it is important to know that all the requirements are verified and validated in order to maintain a good reputation and standard. Today ThyssenKrupp Marine Systems AB does not have a clear traceability between requirements and verification. In order to improve and create a clear formal traceability for their developing process a traceability examination ha

En jämförelse mellan två prototypdon med avseende på spridningsbild och tryckfall

I rådande klimat och omvärldsläge har energianvändning fått ett allt större fokus än vad det hade för en 5 – 10 år sedan. Företag och regioner har blivit alltmer medvetna om energikostnaderna där en av de största punkterna är uppvärmning och nedkylning av lokaler. Ett sätt att minska energianvändningen är att kyla ner visa zoner i stället för hela lokalen. Detta lämpar sig i lokaler med höga krav In current times due to climate change and the geopolitical environment, more emphasis has been placed on energy usage compared to 5 – 10 years ago. Companies and Counties have become more aware of the energy costs, where one of the biggest posts are heating and cooling indoor spaces. One way of lowering the energy usage of buildings is that instead of cooling the whole indoor space only certain z

Leverantörs tillgång till information vid överprövning av upphandling – Metoder för anskaffning och tillgång till information efter parts- och domstolsaktivitet i mål om överprövning av offentlig upphandling

Vid överprövning av en offentlig upphandling är information absolut nödvändigt för sökande leverantör. För bifall till yrkandet krävs att sökanden åberopar rättsligt relevanta omständigheter och för dessa i bevis. Hela sökandens processföring som sådan emanerar från den information som denna har tillgång till. Denna uppsats utreder hur en leverantör – efter egen aktivitet samt med hjälp av domstolInformation is an absolute necessity for a supplier when applying for a review procedure of a procurement. To succeed with the application, the supplier needs to fulfil its burden of invoking certain legally relevant facts, as well as its burden of proof for said facts; all of which require access to information. This paper investigates how said supplier – on its own in addition to with the assist

Fördrivning av socialbidragstagare i Sverige: Problemrepresentationer hos kommuner och organisationer i civilsamhället

Denna studie undersöker fördrivning av socialbidragstagare, ett fenomen som uppmärksammades i media hösten 2020 under namnet ”social dumpning”, vilket beskrev hur kommuner runt om i landet genom socialtjänsten aktivt tvingar personer i behov av ekonomiskt bistånd att flytta till andra kommuner. Genom intervjuer med anställda i kommuner som tagit emot fördrivna socialbidragstagare samt civilsamhällThis study examines displacement of people in need of social assistance in Sweden, a phenomenon that received media attention during the fall of 2020 under the name “social dumping”, that describes how municipalities around the country actively forces people to move to other municipalities. Through interviews with employees within municipalities who have received displaced people in need of social

The Complex User of Sustainable Technologies – A qualitative study of factors that enable and constrain consumers to adopt food waste reduction apps

Thesis purpose: The aim of this study is to identify enablers and constraints for consumers to adopt food waste reduction apps. Consequently, it contributes to the field of innovation diffusion and, importantly, consumer adoption of technological innovations. Methodology: This exploratory study uses qualitative methods to investigate consumer values, expectations and experiences as the main unit

Piece by Piece

The growth of informal settlements especially in third world countries has become a problem on a global scale. In Asia and Africa, although under different circumstances, the fastest urbanization takes place. To find a good way on how to include the poor city migraters into the growing cities will be crucial in order to have more sustainable, peaceful and just societies. My focus lays on the semi-

Cultural Heritage & Brand Communication - Case Study Sofiero Castle & Castle Park

This study examines the effect of different organizational aspects on the internal brand communication of an organization in the context of cultural heritages. As cultural tourism is growing and becoming more competitive, this particular tourism branch has to be introduced to internal brand communication to provide a good base for branding. The topic has been studied in a case study. As a case Sof

"Vi som överlevt helvetet" : Kvinnor i missbruk berättar om våld

Violence against women with experience of substance abuse is a complex issue where both violence and substance abuse aggravate each other, creating social situations difficult to break up from. Social services tend only to categorise these women as substance abusers, concealing their status as victims of violence and leading to inadequate support. To further understand these women’s experiences of

"Men just vad det gäller droger så är det ju - tyvärr handlar det om att släcka bränder." : Skolkuratorers drogförebyggande arbete med elever i grundskolan.

The purpose of this study was to examine how school counselors work with pupils in a drug preventive way and furthermore to examine possibilities, obstacles and efficiency experienced by school counselors in that work. In order to achieve the purpose of the study seven qualitative semi-structured interviews were conducted with school counselors. The interviews were transcribed, coded and analyzed

Climate change adaptation strategies for urban stormwater management : a comparative study of municipalities in Scania

Skåne är en region sårbar för klimatförändringar och klimatmodeller förutspår en ökning av extrem nederbörd i länet. Nederbördsrelaterade översvämningar i tätorter förknippas med en intensiv nederbörds mängd, de många ogenomträngliga ytor i städer samt överbelastning av avloppssystem. År 2014 publicerades en regional handlingsplan för klimatanpassning av Länsstyrelsen i Skåne. I den beskrivs dagvaScania is a region vulnerable to climate change and climate models project an increase in extreme precipitation events for this area. Pluvial flooding in urban areas is mostly associated with the large amount of impermeable surfaces and sewer system overload. In 2014 the County Administrative Board of Scania released a regional action plan for adaptation strategies and stormwater is described as a