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Short-chain fatty acids (SCFA) are involved in immune system and inflammatory responses. We comprehensively assessed the host genetic and gut microbial contribution to a panel of eight serum and stool SCFAs in two cohorts (TwinsUK, n = 2507; ZOE PREDICT-1, n = 328), examined their postprandial changes and explored their links with chronic and acute inflammatory responses in healthy individuals and

Coherent InP nano-sized islands, embedded into GaInP, have been grown by metal-organic vapour phase epitaxy using the Stranski-Krastanow growth mode. Photoluminescence, atomic force microscopy and transmission electron microscopy studies show that the insertion of a thin similar to 4 monolayer thick GaP layer affects the critical thickness of the subsequently deposited two-dimensional InP wetting Coherent InP nano-sized islands, embedded into GaInP, have been grown by metal-organic vapour phase epitaxy using the Stranski-Krastanow growth mode. Photoluminescence, atomic force microscopy and transmission electron microscopy studies show that the insertion of a thin ∼ 4 monolayer thick GaP layer affects the critical thickness of the subsequently deposited two-dimensional InP wetting layer, in

Objectives: Genome-wide association studies have revealed over 200 genetic susceptibility loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be generated to predict risk of PCa. We summarize the published evidence and conduct meta-analyses of PRS as a predictor of PCa risk in Caucasian men. Patients and methods: Data were extracted from 59 studies, with 16 studies i

Background: Conservative management is an option for prostate cancer (PCa) patients either with the objective of delaying or even avoiding curative therapy, or to wait until palliative treatment is needed. PIONEER, funded by the European Commission Innovative Medicines Initiative, aims at improving PCa care across Europe through the application of big data analytics. Objective: To describe the cli

Primary and secondary bile acids (BAs) influence metabolism and inflammation, and the gut microbiome modulates levels of BAs. We systematically explore the host genetic, gut microbial, and habitual dietary contribution to a panel of 19 serum and 15 stool BAs in two population-based cohorts (TwinsUK, n = 2,382; ZOE PREDICT-1, n = 327) and assess changes post-bariatric surgery and after nutritional

Focusing on the photoinduced electron transfer properties of the D-D-A molecule ((TPA-TT)-BODIPY-C60) in an external electric field (Fext), the excited-state properties in which the double-donor molecule is excited to form three charge-separated states were simulated. The charge-Transfer processes of these three charge-separated states were investigated by considering the two donors as a whole ((T

Popular Abstract in Swedish Ju tidigare man kan upptäcka sjukdomskopplade förändringar i kroppen, desto större är chansen att bli frisk och överleva sjukdomen. Molekylär avbildning är ett nytt forskningsfält som vuxit fram de senaste årtiondena som svarar mot detta önskemål. Målet är att så tidigt som möjligt kunna avbilda de förändringar som ger upphov till sjukdomen, snarare än att som idag, avbThe earlier abnormalities coupled with disease can be discovered in the body, the larger is the chance to survive the disease. Molecular imaging is a growing research field which aims to detect these abnormalities at a molecular level, when the chance of survival is still high. The main idea of molecular imaging is to use target specific contrast agents that accumulate at the diseased region at a

Assessment of respiratory tract deposition of nanoparticles is a key link to understanding their health impacts. An instrument was developed to measure respiratory tract deposition of nanoparticles in a single breath. Monodisperse nanoparticles are generated, inhaled and sampled from a determined volumetric lung depth after a controlled residence time in the lung. The instrument was characterized

The signal crayfish (Pacifastacus leniusculus) was introduced to Sweden in 1960, and it has a high commercial and recreational value, but it may also have negative effects on native ecosystems. To better predict how climate warming will affect population dynamics of this cool-water crayfish, we explored the role of temperature and density dependence as explanatory factors of the subsequent years’

Mutations in the CFTR gene result in impaired host defense during cystic fibrosis (CF), where Pseudomonas aeruginosa becomes a key pathogen. We investigated the expression pattern of the antibacterial growth factor midkine in CF and possible interference with its activity by the altered airway microenvironment. High midkine expression was found in CF lung tissue compared with controls, involving e

Viruses are the most abundant and genetically diverse entities on Earth, yet the functions and evolution of most viral proteins remain poorly understood. Their rapid evolution often obscures evolutionary relationships, limiting the ability to assign functions using sequence-based methods. Although the conservation of protein fold can reveal deep homologies, viral proteins remain underrepresented i

Denna uppsats handlar om användning av artificiell intelligens i skol- och utbildningsmiljö, samt de potentiella utmaningar och hinder som finns för artikel 5(1)(a) AI förordningen, att försäkra uppfyllandet av barns rätt till tanke- och samvetsfrihet, i artikel 14 Barnkonventionen. De aktuella frågeställningarna i denna uppsats är: Hur försäkrar artikel 5(1)(a) AI förordningen uppfyllandet av baThis thesis investigates the use of AI within the educational environment, specifically the school environment, and the potential challenges and barriers for article 5(1)(a) AI Act, to ensure the realization of the children’s right to freedom of thought and conscience, under article 14 UNCRC. The research questions are: How does article 5(1)(a) AI Act ensure the realization of the children’s righ

Background and objective: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is an evolving diagnostic tool for prostate cancer. There is a need to harmonise existing guidelines and reporting recommendations for PSMA PET/CT. The Standardised PSMA PET/CT Analysis and Reporting Consensus (SPARC) project aims to consolidate classifications and recommen

Background and objective: Although cardiovascular toxicity from modern systemic treatments in metastatic hormone-sensitive prostate cancer (mHSPC) remains a concern, real-world data are limited. We aimed to characterise patients treated for mHSPC across multiple large cohorts and estimate cardiovascular adverse event (AE) risks. Methods: Leveraging PIONEER's Big Data platform, with databases stand

Correlated electron physics is intrinsically a multiscale problem, since high-energy electronic states screen the interactions between the correlated electrons close to the Fermi level, thereby reducing the magnitude of the interaction strength and dramatically shortening its range. Thus the handling of screening is an essential ingredient in the first-principles modeling of correlated electron sy

By combining ab initio downfolding with cluster dynamical mean-field theory, we study the degree of correlations in monolayer, bilayer, and bulk breathing-mode kagome van der Waals materials Nb3(F, Cl, Br, I)8. Our new material-specific many-body model library shows that in low-temperature bulk structures the Coulomb correlation strength steadily increases from I to Br, Cl, and F, allowing us to i

14 Utbildningsplan Musikerutbildning cembalo, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, cembalo. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: CEMB. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft HT-17

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_cembalo_kand.pdf - 2026-05-23

10 Utbildningsplan Musikerutbildning gitarr, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, gitarr. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: GITA. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft HT-17.

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_gitarr_kand.pdf - 2026-05-23

8 Utbildningsplan Musikerutbildning piano, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, piano. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: PIAN. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft HT-17. 3.

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_piano_kand.pdf - 2026-05-23