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The dangerous path to school and empowerment: a case study investigating the difficulties of empowerment in education for girls in West Kalungu County District, Uganda
Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins
Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T
Prevention and Management of Bleeding Episodes in Children with Hemophilia
Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat
Toward clinical use of the IgG specific enzymes IdeS and EndoS against antibody-mediated diseases
IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.
EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca
Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami
Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions
Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti
Investigation of bubble departure radius in subcooled pool boiling under microgravity condition
Induction of platelet thrombi by bacteria and antibodies.
We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai
AI Lund Lunch seminar: The Challenges of Generative AI for Democracy – Trust, Transparency, and Accountability in an AI-Infused Information Landscape
AI Lund Lunch seminar: The Challenges of Generative AI for Democracy – Trust, Transparency, and Accountability in an AI-Infused Information Landscape
The Workers the Work Environment Discourse Forgot - a critical analysis of the official psychosocial work environment discourse in Sweden
Purpose: To explore how the changes in work life, here represented and depicted through the concepts of knowledge work and knowledge worker, have been incorporated in the official psychosocial work environment discourse in Sweden. Methodology: Critical discourse analysis, contrasting the official psychosocial work environment discourse to literature on knowledge work and knowledge worker, to explo
Using Eye tracking technology to study digital writing processes.
Nyhetsbrev Från GÅS-projektet Mars 2025
Nyhetsbrev från GÅS-projektet mars 2025 Professor Sölve Elmståhl har ordet Temat för detta nyhetsbrev är nya forskningsfynd i GÅS-studien. Show as web page I detta nyhetsbrev berättar vi om aktuella forskningsfrågor och resultat som utgår ifrån insamlade data från GÅS- projektet. Fler projekt rör riskfaktorer för vanliga kroniska sjukdomar som nedsatt njur- och lungfunktion, högt blodtryck och på
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A simulation model of a reactor for ethylene oxide production
There are high demands on companies today to survive when competition is high and that also applies to companies that manufacture ethylene oxide. The raw material in the production of ethylene oxide is ethylene and oxygen where ethylene is the largest cost. To facilitate the reaction a catalyst, which increases the reaction rate, is used. The catalyst has a major influence on the efficiency and ec
Dabigatran eller warfarin vid elkonvertering i Region Skåne? – En kostnadsminimeringsanalys
Paraidrottare – dubbel kamp mot skador och sjukdomar – Vetenskap och Hälsa
Paraidrottare – dubbel kamp mot skador och sjukdomar – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Paraidrottare – dubbel kamp mot skador och sjukdomar 2019-12-10 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. iStock/nautiluz56 Parasporten växer sig allt
https://www.vetenskaphalsa.se/paraidrottare-dubbel-kamp-mot-skador-och-sjukdomar/ - 2026-05-26
Aerospace Electric Generator Specification and Selection - Opportunities and Challenges
The goal of this work is to specify and investigate suitability of a number of selected permanent magnet synchronous machine (PMSM) topologies to be mounted directly on a low pressure shaft (LPS) of a geared turbofan engine. The starting point of the work is to explore the status of electrical machines for more electric engine in order to study different design aspects when identifying and definin
