Search results

Antikroppar har ett brett användningsområde med stor potential men det är svårt att skapa stabila lösningar. Den strukturella stabiliteten är en viktig faktor när man väljer läkemedelskandidater, och i de tidiga utvecklingsstadierna görs prediktiva undersökningar för att ta reda på varje kandidats stabilitet och utvecklings-potential. Därmed är det av största intresse att utvärdera hur antikropparA great challenge during early development of medicinal antibodies is to determine the stability of the candidates. This is required to be able to select the candidates with the greatest developability. The stability of the candidates can be estimated using different orthogonal techniques and the aim of this investigation was thus to use orthogonal techniques for the investigation of conformationa

MERGE (ModElling the Regional and Global Earth system) står för modellering av jordens klimatsystem, med fokus på vegetation och terrestra ekosystem. Målet för den nationella strategiska plattformen är att öka kunskapen om klimatet med speciellt fokus på hur atmosfär, markyta, vegetation och ekosystem samverkar. Verksamheten omfattar avancerad forskning, disciplinär och tvärvetenskaplig forskarutbMERGE is a Strategic Research Area working with modelling the regional and global Climate System with focus on the interactions between the climate and the terrestrial biosphere. MERGE brings together more than 150 researchers collaborating across five Swedish universities - Lund University, Chalmers, University of Gothenburg, KTH and SMHI. The cutting-edge research environment are experts on the

We previously reported that soluble decay-accelerating factor (DAF) and coxsackievirus-adenovirus receptor (CAR) blocked coxsackievirus 133 (CVB3) myocarditis in mice, but only soluble CAR blocked CVB3-mediated pancreatitis. Here, we report that the in vitro mechanisms of viral inhibition by these soluble receptors also differ. Soluble DAF inhibited virus infection through the formation of reversi

Epidemiologi för hälsa - en gemensam satsning för Lund och Uppsala universitet för nationell och internationell excellensEpidemiology for health - a joint initiative between Lund and Uppsala universities for national and international excellence

In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that prevent neuronal growth and synaptic plasticity. The brain's ECM plays a crucial role in network formation, development, and regeneration of the c

BioMS is the national infrastructure for biological mass spectrometry (MS). BioMS offers access to qualified projects in proteogenomics, targeted protein quantitation, glycoproteomics, hydrogen-deuterium exchange MS, glycomics, lipidomics, and chemical proteomics. Detailed information and the project application forms can be found at www.bioms.se. BioMS is hosted by Lund University with support fr

Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T

I över femtio år har Teaterhögskolan i Malmö utbildat skådespelare som verkat på svenska och internationella scener, i film, radio och tv. Skolan har ett gediget rykte som en av Nordens ledande teaterutbildningar med ett tydligt metodiskt förhållningssätt, en medveten pedagogisk progression och en konsekvent syn på teaterns kunskapskärna som handlingsbaserad. Teaterhögskolan har funnits i Malmö, sFor over fifty years Malmö Theatre Academy has trained professional actors working in theatre, film, radio, and TV nationally and internationally. It has a solid reputation as one of the Nordic region's leading theater educations with a clear methodological approach, a conscious pedagogical progression, and a consistent view of the theater's core knowledge as action based. The academy is based in

Color is the most obvious and easily determined soil property that can provide crucial information about soil composition. The NIX™ Pro color sensor (Nix) presents a user-friendly alternative to the traditional Munsell manual method, with reduced sensitivity to environmental and human factors. Therefore, a new method was developed to use Nix in combination with machine learning to quickly and affo