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Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function

Angiogenesis is a hallmark of cancer and is now a validated therapeutic target in the clinical setting. Despite the initial success, anti-angiogenic compounds impinging on the vascular endothelial growth factor (VEGF) pathway display limited survival benefits in patients and resistance often develops due to activation of alternative pathways. Thus, finding and validating new targets is highly warr

Surface Properties of Antigen-Antibody Complexes

In this paper, the authors show that liquid-liquid partition chromatography in an aqueous two-phase system offers unique possibilities of comparing the overall surface properties of intact antibodies in solution before and after binding of antigen. The authors demonstrate that the surface properties of antigen-antibody complexes are dependent on the variable regions of the antibodies, the nature o

Affinity fractionation of lymphocytes using a monolithic cryogel.

A new type of continuous, supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing specific fractionation and separation of human peripheral blood lymphocytes in a chromatographic format. The affinity adsorbent was used to design a novel cell separation strategy, which was based on the interaction of protein A from Staphylococcus aureus with cells bearing IgG antibodies on

Body descriptions in biohacking and their overlaps and origins : a Swedish case study

This article researches what body descriptions are present within Swedish biohacking, what roots they have, and what overlaps they create between biohacking and other philosophical, political, and scientific discourses. As biohacking has become an increasingly popular subcultural influence incontemporary culture, not least when it comes to individual responsibility for ones health, the aim of the

Policy för akademiskt ledarskap på Lunds universitet

Policy for academic leadership at Lund University Universitetet beslutade om Lunds universitets policy för akademiskt ledarskap den 11 januari 2024. Innehåll på sidan:Frågor och svar om policy för akademiskt ledarskap på Lunds universitetRelaterade dokumentSjälvskattningstest: Reflektera och skatta dig själv i ditt ledarskap utifrån förväntade kompetenser och önskvärda färdigheter i policyn för ak

https://www.hr-webben.lu.se/chefsplattformen-chef-och-ledarutveckling-pa-lunds-universitet/policy-akademiskt-ledarskap-pa-lunds-universitet - 2026-05-27

HR-information kopplad till situationen i Ukraina

Längre ned på sidan: Information in English Stöd och guidning för dig som arbetar med HR-frågor Arbetsrättsliga lagar och avtal gäller som vanligt Vid höjd beredskap - kris- och krigsplacering? Massflyktsdirektivet och möjligheten att anställa personer från Ukraina Uppehållstillstånd som är på väg att gå ut Vilken status har våra arbetsrättsliga lagar i denna situation? Vad betyder anställning uti

https://www.hr-webben.lu.se/hr-information-kopplad-till-situationen-i-ukraina - 2026-05-27

Förvärvade riktlinjer : en diskursanalytisk kartläggning av förvärvspolicys på svenska forskningsbibliotek

Recent years have seen many changes to the library field, not least when it comes to acquisitions. Internationally, the concept of letting library users take part in the acquisition process has developed over the past 30 years, from looking at inter-library loan applications as purchase requests to systems such as Patron-Driven Acquisitions (PDA). In a Swedish context, user influence has long been

Studies of molecular mechanisms of telomere maintenance in Naumovozyma castellii

POPULAR SCIENTIFIC SUMMARYI was on my way home, sitting on the bus. My tired eyes swept through the pages of the local newspaper and that was the moment I met Lisa. She had previously been diagnosed with cancer. She had recovered and was back to her daily life. Unfortunately the cancer has come back and it has spread to several organs. Lisa as a mother of two kids, as a wife, as a daughter, as a sTelomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins.When a cell replicates its chromosomes, a certain piece of DNA is lost from chromosomal ends due to the ´´ end replication problem´´. This progressive shortening of telo