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Retrograde and transganglionic labeling techniques are commonly used to visualize subsets of neurons and sensory afferent projections in the nervous system. These methods commonly require anesthesia and surgical methods. However, some tracers can also be administered systemically in awake animals, thus reducing risks associated with anesthesia and surgery and allowing for labeling of neuronal popu
In August 2008, Georgia was engaged in an internal armed-conflict with its breakaway region of South Ossetia, which shortly after, grew into a large-scale war with Russian Federation. In the course of the war, hundreds of civilians became victims of the international crimes committed by belligerent sides. Hence, the central issue of my research is a post-conflict justice. In particular, if there e
This book is a reprint of the Special Issue Sustainable Healthy Working Life for All Ages - Work Environment, Age Management and Employability that was published in IJERPH.
This article looks at upcycling and the library of things from intellectual property law perspective
Newly diagnosed breast cancer (BC) patients with clinical T1–T2 N0 disease undergo sentinel-lymph-node (SLN) biopsy, although most of them have a benign SLN. The pilot noninvasive lymph node staging (NILS) artificial neural network (ANN) model to predict nodal status was published in 2019, showing the potential to identify patients with a low risk of SLN metastasis. The aim of this study is to ass
Background: The 2030 agenda for sustainable development calls upon all nations to make critical investments in their health systems to deliver universal access to Sexual and Reproductive Health and Rights (SRHR). Capacity development is listed among the strategies for achieving sustainable development goals. Although capacity development has been a major component of international development for
Aims/hypothesis: The aim of this work was to study the incidence over time of lower extremity amputations and determine variables associated with increased risk of amputations in people with type 1 diabetes. Methods: Individuals with type 1 diabetes registered in the Swedish National Diabetes Registry with no previous amputation from 1 January 1998 and followed to 2 October 2019 were included. Tim
A search for dark-matter particles in events with large missing transverse momentum and a Higgs boson candidate decaying into two photons is reported. The search uses 139 fb−1 of proton-proton collision data collected at s = 13 TeV with the ATLAS detector at the CERN LHC between 2015 and 2018. No significant excess of events over the Standard Model predictions is observed. The results are interpre
Two conspicuous wet shifts in the peat stratigraphy of Store Mosse in southern Sweden, associated with bog-wide changes in vegetation and degree of peat decomposition, were analysed at high resolution. The bog-surface wetness (BSW) proxy data (organic matter bulk density, C/N ratio, plant macrofossils and testate amoebae) highlight the importance of interactions between vegetation composition, mic
Background: Chronic pain patients frequently suffer from psychological symptoms. There is no consensus concerning the prevalence of severe anxiety and depressive symptoms and the strength of the associations between pain intensity and psychological distress. Although an important aspect of the clinical picture is understanding how the pain condition impacts life, little is known about the relative
The results of a search for new heavy W′ bosons decaying to an electron or muon and a neutrino using proton–proton collision data at a centre-of-mass energy of s=13 TeV are presented. The dataset was collected in 2015 and 2016 by the ATLAS experiment at the Large Hadron Collider and corresponds to an integrated luminosity of 36.1 fb-1. As no excess of events above the Standard Model prediction is
Background: Previous research suggests that sleep problems may be an important predictor for chronic widespread pain (CWP). With this study we investigated both sleep problems and fatigue as predictors for the onset of CWP over a 5-year and an 18-year perspective in a population free from CWP at baseline. Methods: To get a more stable classification of CWP, we used a wash-out period, including onl
Background and Aims: Incisional hernia development is a frequent long-term sequel after open abdomen treatment. This report describes a novel technique, the vacuum-assisted wound closure and permanent onlay mesh–mediated fascial traction for temporary and final closure of the open abdomen, with the intention to decrease incisional hernia rates. Primary aim was to evaluate incisional hernia develop
Background: Many existing patient-reported outcome measures are extensive regarding both patient burden and administration, and in terms of analysing and reporting results. The VascuQoL-6 (VQ6) - a short version of the original Vascular Quality of Life Questionnaire (VascuQoL), a disease-specific instrument for peripheral arterial disease - was recently developed. However, the VQ6 has not yet been
Based on small to moderate effect sizes for the wide range of symptomatic treatments in osteoarthritis (OA), and on the heterogeneity of OA patients, treatment guidelines for OA have stressed the need for research on clinical predictors of response to different treatments. A meta-analysis to quantify the effect modified by the predictors using individual patient data (IPD) is suggested. The initia
Pinus sylvestris (tall) är en betydelsefull trädart i Sverige och Europa, både ekonomiskt och kulturellt sett. Trädet infekteras dock av den destruktiva rottickan (Heterobasidion spp.) vilket resulterar i stora ekonomiska förluster inom skogsindustrin, med en uppskattad monetär förlust på ca 800 miljoner EUR årligen i Europa. Det är svårt att upptäcka svampen i tidiga infektionsstadier eftersom inPinus sylvestris (Scots pine) is an important tree species in Sweden and Europe, both economically and culturally. However, the highly destructive root rot fungi Heterobasidion spp. infect P. sylvestris and cause major economic losses in the forest industry, estimated to about 800 million EUR annually in Europe alone. Detection of the fungus in early stages is hard, as the infection mainly stays i
