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Pyrazinamide (PZA) is a potent first-line agent for the treatment of tuberculosis (TB) with activity also against a significant part of drug-resistant Mycobacterium tuberculosis strains. Since PZA is active only at acid pH, testing for susceptibility to PZA is difficult and insufficiently reproducible. The recommended critical concentration for PZA susceptibility (MIC, 100 mg/liter) used in the Ba
Many extensions of the Standard Model predict the existence of charged heavy long-lived particles, such as R-hadrons or charginos. These particles, if produced at the Large Hadron Collider, should bemoving non-relativistically and are therefore identifiable through the measurement of an anomalously large specific energy loss in the ATLAS pixel detector. Measuring heavy long-lived particles through
A search for a massive [Formula: see text] gauge boson decaying to a top quark and a bottom quark is performed with the ATLAS detector in [Formula: see text] collisions at the LHC. The dataset was taken at a centre-of-mass energy of [Formula: see text] and corresponds to [Formula: see text] of integrated luminosity. This analysis is done in the hadronic decay mode of the top quark, where novel jet
Background: The intervention; "Continuum of Care for Frail Older People", was designed to create an integrated continuum of care from the hospital emergency department through the hospital and back to the older person's own home. The aim of this study is to evaluate the effects of the intervention on functional ability in terms of activities of daily living (ADL). Methods: The study is a non-blind
Helicobacter species are fastidious bacterial pathogens that are difficult to culture by standard methods. A PCR-denaturing gradient gel electrophoresis (PCR-DGGE) technique for detection and identification of different Helicobacter species was developed and evaluated. The method involves PCR detection of Helicobacter DNA by genus-specific primers that target 16S rDNA and subsequent differentiatio
As legislators in recent years have adopted regulations demanding companies to disclose information on their supply chains, a new chapter of corporate transparency has been opened. However, what power such regulations have to initiate a change of corporate behaviour is questionable. In this thesis the most topical of the recently adopted supply chain transparency and due diligence regulations, are
Denna uppsats undersöker hur Khasifolket och dess matrilinjära samhällsstruktur framställs i den rikstäckande dagstidningen “The Times of India”. En matrilinjär samhällsstruktur bygger på kvinnlig arvsrätt. Undersökningen görs mot bakgrund av att tidigare forskning inom fältet media och kommunikation inte gjorts gällande Khasifolket. Genom att använda Van Dijks kritiska diskursanalys vid övergripa
“The buck stops here”. Så stod det skrivet på det lilla plakatet på president Trumans skrivbord. Detta budskap, lika allmängiltigt idag som 1953, borde verka som en påminnelse om värdet av ansvar och möjligheten till utkrävande av detsamma från alla instutioner och personer med inflytande över människors liv och välmående. Privata militära aktörer är idag aktiva över hela världen och är involverad“The buck stops here”, as was the wording on the famous sign on President Truman’s desk, should remind us today - as it reminded all Americans of the virtues of accountability and responsibility in 1953 - that any office or person that holds influence over the lives of others needs to be able to be held accountable for their actions. Today, Private Military Companies - or PMCs for short - are depl
Nya skyldigheter för utländska företag verksamma i Sverige infördes den 1 januari 2021. Trots frånvaron av ett fast driftställe i Sverige eller annan skattskyldighet, ska skatteavdrag för preliminär inkomstskatt göras från betalningar för arbete som ett utländskt företag utför i Sverige. Den innehållna skatten kan återbetalas, men tidigast efter att ett beslut om slutlig skatt har fattats efter räNew obligations for foreign companies operating in Sweden have been introduced on 1 January 2021. Despite the absence of a Swedish PE or other tax liability, payments for work performed in Sweden by foreign companies is subject to a requirement of withholding preliminary income tax. A refund of the withheld amount can be granted, but only once a final tax assessment has been completed after the en
This study describes an aggregate relationship between exchange rate risk and foreign direct investments. The relationship is conducted by panel data estimations, with variables derived from the OLI-framework and prior research. Sample data consists of 36 countries for the time series 1991-2009. Estimations are controlled for country specific variations by using fixed effects, regional dummy varia
Background: For locally advanced Siewert type II and III tumors we have performed total gastrectomy including resection of the distal 2/3 of the esophagus, through separate abdominal and right chest incisions (THX-ABD). The procedure involves wide lymphadenectomy in the abdomen/chest and a Roux-en-Y jejunostomy to the level of the azygos vein or above. The aim of the study was to investigate short
After the disintegration of the Soviet Union, the national identities of the Eastern and Central European states are finding themselves in a process of transformation and the results are having an impact on international relations in the region. National and foreign political identities of states are constituted by means of everyday discursive practices, not least in the media. In the present stud
A novel optical design for a flexible SAXS beamline at a modern synchrotron has been implemented for the CoSAXS beamline at the 3GeV ring at the MAX TV Laboratory. The performance of the beamline has been simulated through combined ray tracing and wave propagation with the code xrt taking into account the low emittance and highly coherent beam of MAX TV and the short inter-optics distances of the
Objectives To use the estimates from the Global Burden of Disease Study 2016 to describe patterns of suicide mortality globally, regionally, and for 195 countries and territories by age, sex, and Socio-demographic index, and to describe temporal trends between 1990 and 2016. Design Systematic analysis. Main outcome measures Crude and age standardised rates from suicide mortality and years of life
We present 77 new granite whole-rock analyses from the Qattar and Gharib areas, Eastern Desert, Egypt. Both areas include a “normal” granite and either a hypersolvus (Gharib) or an almost plagioclase-free granite (Qattar) enriched in fluorite. According to earlier results, F influences element distribution in granitic melts forming complexe
