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Laminins are basement membrane components that regulate a plethora of biological processes. Despite decades of research, the exact roles of laminins in different tissues and in organogenesis remain to be elucidated. Here, we investigated the function of laminin γ1 chain in heart, lung and other tissues by generating a mouse that lacks laminin γ1 in cells expressing SM22α (Tagln) (LMγ1 flox/SM22α C
Intravenous thrombolysis with tissue plasminogen activator is the only proven acute therapy for ischemic stroke. This therapy has not been translated into clinical practice in the developing world primarily due to economic constraints. Streptokinase, a lower cost alternative thrombolytic agent, is widely available in developing countries where it is utilized to treat patients with acute coronary s
Corporate mergers and acquisitions (M&As) are prominent means for corporate strategy. In many M&As information systems (IS), integration is critical for achieving the intended goals. By integrating previous research on M&A and IS integration, we develop a six-dimensional theoretical framework for IS integration in corporate M&As. The framework is used to describe and explain IS int
The relation between use of sunscreens, different host factors and malignant melanoma was investigated in a population-based, matched case-control study of malignant melanoma in the South Swedish Health Care Region, which has the highest risk for melanoma in Sweden, between 1 July 1988 and 30 June 1990. In total, 400 melanoma patients and 640 healthy controls aged 15-75 years answered a comprehens
This paper reports the interim results of an ongoing systematic review of the available evidence for the effectiveness of nursing care for people with Parkinson's disease (PD). Five clinical and four health-economic evaluations suggest that the clinical and cost effectiveness of nursing care for PD remain inconclusive. This is in contrast to clinical experience and may be due to issues related to
Pancreatic Ductal Adenocarcinoma (PDAC) is a very aggressive disease, lacking effective therapeutic approaches and leaving PDAC patients with a poor prognosis. The life expectancy of PDAC patients has not experienced a significant change in the last few decades with a five-year survival rate of only 8%. To address this unmet need, novel pharmacological targets must be identified for clinical inter
Titti MattssonBarnet och rättsprocessen: Rättssäkerhet, integritetsskydd och autonomi i samband med beslut om tvångsvårdDatum för disputation: den 9 november 2002Fakultetsopponent: professor Trude HaugliÄmne: socialrättAbstractVad är barnets bästa i en domstolsprocess? Hur skall barns behov och intressen tillvaratas under utredningsarbete och beslut, och av vem? I vilken utsträckning skall barn få
https://www.jur.lu.se/forskning/disputationer/disputationer-2002 - 2026-07-03
23 mars 2026 14:15 till 15:00 | Seminarium A Physical Chemistry seminar by Dr. Benedetta Rosi, European Spallation Source (ESS), LundWhen: 23 March, 14:15-15:00Where: Lecturehall KC:MTitle: Title: Investigations on the segmental dynamics of polymers in permanent and transient networks by neutron spectroscopy methodsAbstract: Viscoelastic and transport properties of polymers have both theoretical a
https://www.kilu.lu.se/evenemang/physical-chemistry-seminar-benedetta-rosi - 2026-07-03
When corporations are faced with accusations of crime, they usually find it necessary to justify their actions to the public, the media and their shareholders. Corporate self-defense, aimed at protecting a corporation’s image and legitimacy, belongs to a broader category of offenders’ denials and neutralizations. The objective of this article is to compile and discuss literature that is of value f
This master thesis explores the usage of stainless steel in mobile phones. The first part is an introduction to stainless steel which explains the properties of the different stainless steels, and also the most common methods used for sheet metal production. It is concluded with a selection process to determine which stainless steels are best suited to be used at Sony Ericsson Mobile Communication
In this article I examine whether an influential theory of mechanisms proposed by Peter Machamer, Lindley Darden and Carl Craver can accommodate polygenic effects. This theory is both interesting and problematic, I will argue, because it ascribes a central role to activities. In it, activities are needed not only to constitute mechanisms but also to perform their causal role. These putative functi
The aim of this article is to reflect on the evolution of total quality management (TQM) as the most widespread quality management approach during the last 25 years. However, during the first 10 years of the new millennium, the term TQM seems to have lost its attractiveness in Western parts of the world and instead new terms such as Business Excellence, Organisational Excellence, Six Sigma, and Le
