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Therapeutic peptides are a fast-increasing segment in the pharmaceutical industry, and GLP-1 analogues stood for two out of the three most sold drugs last year, 2025. The most common production method of peptides is based on Merrifield’s discovery of solid-phase peptide synthesis (SPPS), which uses large volumes of hazardous chemicals like N,N-dimethylformamide (DMF), piperidine, and trifluoraceti
Electricity demand in southern Sweden is expected to increase significantly in the coming decades. More electric cars, cleaner industries, and the phase-out of fossil fuels will require much larger amounts of electricity than today. At the same time, Skåne currently produces only part of the electricity it consumes and depends heavily on electricity imports from other regions and neighbouring coun
Various devices rely on invasive biometric identifiers, such as voice and facial recognition, raising privacy concerns. Acoustic handclap control presents a privacy-preserving alternative for interaction with computers, as it does not capture speech or visual data. An analysis of the original implementation suggested that existing classifiers were influenced by environmental bias. With the objecti
1 Stadra 2015 STADRA TEATER Redovisning säsong 2018 2 Grafisk formgivning: Fernemo Information & Grafik AB Text: Magnus Wetterholm Samtliga foton: Dragan Popović, om inget annat anges Tryckt hos: Danagård Litho november 2018 ©Ideella kulturföreningen Cirkustältet STADRA TEATER Prästgatan 26, 713 31 Nora Besöksadress: Teaterfoajén Storgatan 8, Nora 0587-31 13 05 info@stadrateater.se | www.stadratea
https://www.thm.lu.se/sites/thm.lu.se/files/stadra_2018_1205b.pdf - 2026-07-20
Herein, we present KiMoPack, an analysis tool for the kinetic modeling of transient spectroscopic data. KiMoPack enables a state-of-the-art analysis routine including data preprocessing and standard fitting (global analysis), as well as fitting of complex (target) kinetic models, interactive viewing of (fit) results, and multiexperiment analysis via user accessible functions and a graphical user i
Background: Population-based register data could be used to improve our knowledge of patients surgically treated for foot and ankle disorders. The quality register Swefoot was recently created to collect surgical and patient-reported data of foot and ankle surgery. This manuscript aims to describe the development and current use of the register. Methods: The development of Swefoot started in 2014
Blood-based markers (BBMs) have recently shown promise to revolutionize the diagnostic and prognostic work-up of Alzheimer's disease (AD), as well as to improve the design of interventional trials. Here we discuss in detail further research needed to be performed before widespread use of BBMs. We already now recommend use of BBMs as (pre-)screeners to identify individuals likely to have AD patholo
Contemporary research and teaching on global environmental politics (GEP) draw upon many approaches to understanding the ways in which states and societies respond to transboundary environmental problems (see Chapter 2). Approaches that emphasize the state (see Chapter 7) and international organizations (see Chapter 8) derive in a straightforward way from scholarly work in international relations
The construction industry is often described as mature, conservative and resistant to change in research studies, governmental reports as well as in media. Both scholars and policy makers thereby find it critical to encourage innovation, development, and change within the construction industry. This study takes on a different perspective by investigating changes that have actually taken place. The
Chemicals is the industrial sector with the highest energy demand, using a substantial share of global fossil energy and emitting increasing amounts of greenhouse gasses following rapid growth over the past 25 years. Emissions associated with energy use have increased with growth in coal-dependent regions but are also commonly underestimated in regions with higher shares of renewable energy. Renew
Introduction: Due to its universal applicability for early detection and prediction of cancer stage and disease recurrence, widespread implementation of serum-based prostate-specific antigen (PSA) measurements has a significant influence on current treatment strategies for men with prostate cancer (PCa). However, over-detection and the resultant over-treatment of indolent cancers have been strongl
While the Transformer architecture has become ubiquitous in the machine learning field, its adaptation to 3D shape recognition is non-trivial. Due to its quadratic computational complexity, the self-attention operator quickly becomes inefficient as the set of input points grows larger. Furthermore, we find that the attention mechanism struggles to find useful connections between individual points
Ice fragments are generated by sublimation of ice particles in subsaturated conditions in natural clouds. Conceivably, such sublimational breakup would be expected to cause ice multiplication in natural clouds. Any fragment that survives will grow to become ice precipitation that may sublimate and fragment further. As a first step toward assessing this overlooked process, a formulation is proposed
The magnon Hedin's equations are derived via the Schwinger functional derivative technique, and the resulting self-consistent Green's function (GF) method is used to calculate ground state spin patterns and magnetic structure factors for two-dimensional magnetic systems with frustrated spin-12 Heisenberg exchange coupling. Compared with random phase approximation treatments, the inclusion of a sel
BACKGROUND: KRAS mutation can alter the treatment plan after resection of colorectal cancer. Despite its importance, the KRAS status of several patients remains unchecked because of the high cost and limited resources. This study developed a deep neural network (DNN) to predict the KRAS genotype using hematoxylin and eosin (H&E)-stained histopathological images. STUDY DESIGN: Three DNNs were c
The steel industry is a major contributor to emissions of CO2 and key air pollutants. Reducing air pollution has since long been a policy priority in China. Reducing CO2 emissions has more recently also become a key priority partially manifested through the signing of the Paris Agreement in 2015. Although there are often synergies between reducing CO2 emissions and air pollution, it may have impli
The Cherenkov Telescope Array (CTA) will be the next-generation observatory in the field of very-high-energy (20 GeV to 300 TeV) gamma-ray astroparticle physics. Classically, data analysis in the field maximizes sensitivity by applying quality cuts on the data acquired. These cuts, optimized using Monte Carlo simulations, select higher quality events from the initial dataset. Subsequent steps of t
In the last two decades, very-high-energy gamma-ray astronomy has reached maturity: over 200 sources have been detected, both Galactic and extragalactic, by ground-based experiments. At present, Active Galactic Nuclei (AGN) make up about 40% of the more than 200 sources detected at very high energies with ground-based telescopes, the majority of which are blazars, i.e. their jets are closely align
