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BACKGROUND: Immunohistochemical staining for tumor-associated proteins is widely used for the identification of novel prognostic markers. Recently, a tissue-conserving, high-throughput technique, tissue microarray, has been introduced. This technique uses 0.6-mm tissue core biopsy specimens, 500 to 1000 of which are brought into a new paraffin array block, which can be sectioned up to 100 times. M
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Thiol (SH) groups play a remarkable role in the cell with their redox state affecting the activity and structure of many enzymes, receptors and transcription factors. In the present work, carbon paste electrodes modified with sulfhydryl oxidase (SOX) were prepared. The proposed biosensor was based on the monitoring of the produced peroxide concentration that correlates with the concentration of re
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Limitations of the pulse-shape discrimination (PSD) technique - a promising method to identify the charged particles stopped in planar Si-detectors - have been investigated. The particle resolution turned out to be basically determined by resistivity fluctuations in the bulk silicon which cause the charge-collection time to depend on the point of impact. Detector maps showing these fluctuations ha
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Multiple sclerosis (MS) is a chronic disease of the central nervous system, characterized by focal inflammatory lesions with demyelination and axonal loss. It is believed that MS is an immune-mediated disorder with both genetic and environmental contributions to the pathogenesis. Interferons (IFNs) are naturally occurring proteins known to have antiviral, antiproliferative and immunoregulatory eff
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This study deals with the furst attempt at postwar European integration in the defense and foreign policy fields. The European army plan was laid forth by Paris in 1950 after Washington demanded a German contribution to Western defense. Claiming that she could not accept a German presence in NATO, France instead drafted a plan for a supranational, European army. This ill-fated proposal occupied mu
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BACKGROUND: In health economics, health is regarded as part of an individual's human capital. As such it depreciates over time, and investments in health are made in order to keep the stock of health capital at the desired level. Using this framework for analysis of health-related behaviour and Swedish panel data, we examined whether the presence of asthma or allergy affects perceived health and i
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During normal cooking of meat, a class of mutagenic/carcinogenic compounds called heterocyclic amines is formed. Heterocyclic amines are rapidly absorbed and metabolised in the human body, and for estimation of the intake of heterocyclic amines, it is useful to determinate their levels in the urine. Blue Chitin columns were used for the extraction and purification of heterocyclic amines from urine
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The fundamental equations for the theoretical treatment of wood during the process of pyrolysis are presented in Chapter 1. Expressions which must be specially introduced for combustible materials are those which describe the pyrolyctic reaction and reactions at the surface of the material. The reactions are assumed t o conform to first order Arrhenius functions. The treatment also includes the va
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Expression of genes for respiratory chain dehydrogenases was investigated in potato (Solanum tuberosum L. cv. Desiree) leaves. The recently characterized nda1 and ndb1 genes, homologues to genes encoding the non-proton pumping respiratory chain NADH-dehydrogenases of Escherichia coli and yeast, were compared to genes encoding catalytic subunits of the proton-pumping NADH dehydrogenase (complex I).
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The report presents a sample design of a multi-storey building with respect to the fire safety. Three design strategies are examined, a standard solution according to the requirements, a fire safety engineering design without a sprinkler system and finally a fire safety engineering solution with a sprinkler system. Both occupant safety and structural safety have been considered in the design for t
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Cold stress effects on the expression of genes for respiratory chain enzymes were investigated in potato (Solanum tuberosum L., cv. Desiree) leaves. The nda1 and ndb1 genes, homologues to genes encoding the non-proton-pumping respiratory chain NADH dehydrogenases of Escherichia coli and yeast, were compared to genes encoding catalytic subunits of the proton-pumping NADH dehydrogenase (complex I).
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The condensation energy of homogeneous electron gas is calculated within the density-functional theory for superconductors. Purely electronic considerations include the exchange energy exactly and the correlation energy on a level of the random phase approximation. Singlet superconductivity is assumed, and the Coulomb interaction is studied with a model pairing potential at angular momentum up to
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Objectives: To evaluate the use of cellular and cordless telephones as the risk factor For non-Hodgkin's lymphoma (NHL). Methods: Male and female subjects aged 18-74 years living in Sweden were Included during a period from I December 1999 to 30 April 2002. Controls were selected from the national population registry. Exposure to different agents was assessed by questionnalre. Results: In total, 9
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