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The value of bone mineral density (BMD) measurements to stratify fracture probability can be enhanced in a case-finding strategy that combines BMD measurement with independent clinical risk indicators. Putative risk indicators include age and gender, BMI or weight, prior fracture, the use of corticosteroids, and possibly others. The aim of the present study was to develop a mathematical framework
Popular Abstract in Swedish Infektioner i urinvägar, tarm och luftvägar orsakas av bakterier som speciellt anpassats till respektive vävnad. Infektionen börjar med att bakterien binder till slemhinneytan, och därmed sätter igång inflammation och försvar. Urinvägsinfektioner (UVI) är en värdefull modell för att förstå de molekylära detaljerna som avgör balansen mellan värd och bakterie. UVI orsakaBacterial adhesion to the bladder mucosa is a critical step for the establishment of Escherichia coli bacteriuria. The P-fimbriae, encoded by the pap gene cluster, are considered as virulence factors but the mechanisms have been debated. This study defined the roles for P fimbriation during the early colonization of the human urinary tract. Patients with recurrent UTI were first subjected to deli
This paper investigates the feasibility of OCA for ASEAN after the implementation of ASEAN Economic Community Blueprint in 2008. Dynamic Conditional Correlation (DCC) model with and without a structural break are used to identify whether the policy implemented facilitates the region to move closer to a single currency area. Industrial production index growth rate and change in short-term interest
In 2012, the Greater Mekong Sub-region (GMS), an initiative launched by the Asian Development Bank (ADB) to promote regional integration and development between six mainland Southeast Asian countries, will reach its twentieth anniversary. Throughout the past twenty years, the GMS has been considered as highly successful, in comparison with other regional initiatives, in improving connectivity, com
Background: Osteoclasts have been strongly implicated in osteoarthritic cartilage degradation, at least indirectly via bone resorption, and have been shown to degrade cartilage in vitro. The osteoclast resorption processes required to degrade subchondral bone and cartilage-the remodeling of which is important in the osteoarthritic disease process-have not been previously described, although cathep
One of the greatest impediments to the use of probabilistic reasoning in legal arguments is the difficulty in agreeing on an appropriate prior probability for the ultimate hypothesis, (in criminal cases this is normally “Defendant is guilty of the crime for which he/she is accused”). Even strong supporters of a Bayesian approach prefer to ignore priors and focus instead on considering only the lik
Classical homogenization theory based on the Hashin-Shtrikman coated ellipsoids is used to model the changes in the complex valued conductivity (or admittivity) of a lung during tidal breathing. Here, the lung is modeled as a two-phase composite material where the alveolar air-filling corresponds to the inclusion phase. The theory predicts a linear relationship between the real and the imaginary p
The Multi-Blade is a Boron-10-based gaseous thermal neutron detector developed to face the challenge arising in neutron reflectometry at neutron sources. Neutron reflectometers are challenging instruments in terms of instantaneous counting rate and spatial resolution. This detector has been designed according to the requirements given by the reflectometers at the European Spallation Source (ESS) i
Biomedical research projects involving multiple partners from public and private sectors require coherent internal governance mechanisms to engender good working relationships. The DIRECT project is an example of such a venture, funded by the Innovative Medicines Initiative Joint Undertaking (IMI JU). This paper describes the data access policy that was developed within DIRECT to support data acce
For more than 30 years polyimides (PA) have been one of the main polymers for the fabrication of thin film composite membranes. Several researchers have assessed the main fabrication variables that influence the final structure of the polyamide layers including monomer concentration, solvents, additives in aqueous and organic phases and type of support to mention few [1,2]. However, few studies ha
This review describes the history, development, and evolution of cell-based replacement therapy for Parkinson's disease (PD), from the first pioneering trials with fetal ventral midbrain progenitors to future trials using stem cells as well as reprogrammed cells. In the spirit of Tom Isaacs, the review takes parallels to the storyline of Star Wars, including the temptations from the dark side and
The endemic mesosaurid reptiles of the Whitehill-Irati sea in southern Africa and South America during the Permian were studied with preference for the Namibian material. To date three valid mesosaurid species have been described of which two occur on both continents. These mesosaurid aquatic reptiles were among the first evidence used to support the theory of continental drift at the beginning of
A recurring theme in debates on European Union politics is the lack of enthusiasm and involvement of European citizens in the decision-making and legislative procedures, which may appear complex and impermeable. While some scholars deny the existence of a democratic deficit, others fear that continued failure to bridge the gap between the political elite and the constituents will lead to an ever-d
This essay develops a theory for the explanation of the diffrences in succes of Radical Right Populist Parties in Western Europe. In order to create a succesfull radical right populist movement and thus a succesfull radical right populist party, three elements are needed; ?demand?, ?supply? amd ?mobilisation?. Because the creation of a radical right populist movement is different than the creatio
The objective of this thesis is to comprehensively demonstrate the existing extent, and the nature of the Ius Cogens Human Rights Obligations of Transnational Companies and their enforcement in the international law. The existing international human rights law is mainly state-centric as it creates obligations primarily upon States to promote human rights. Apart from that one can outline an affluen
