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Antibiotika-resistens utgör ett ökande hälsoproblem i världen och bakterier blir alltmer resistenta mot de antibiotika vi har att behandla med. Fler bakterier blir också resistenta mot mer än ett antibiotikum och behandling av infektioner med dessa typer av bakterier kompliceras av bristen på effektiva läkemedel vilket leder till ökade sjukvårdskostnader, längre vårdtider och en minskad chans att Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. In this thesis, we present the human milk derived HAMLET (Human Alpha-

We exploit the 7 Ms Chandra observations in the Chandra Deep Field-South (CDF-S), the deepest X-ray survey to date, coupled with CANDELS/GOODS-S data, to measure the total X-ray emission arising from 2076 galaxies at 3.5 ≤ z < 6.5. This aim is achieved by stacking the Chandra data at the positions of optically selected galaxies, reaching effective exposure times of ≥109s.We detect significant (>3.

We review the main software and computing challenges for the Monte Carlo physics event generators used by the LHC experiments, in view of the High-Luminosity LHC (HL-LHC) physics programme. This paper has been prepared by the HEP Software Foundation (HSF) Physics Event Generator Working Group as an input to the LHCC review of HL-LHC computing, which has started in May 2020.

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Halsbränna och sura uppstötningar är vanliga åkommor i den svenska befolkningen där upp till 20 procent av de tillfrågade uppger sig ha besvär av dessa symtom varje vecka. Både halsbränna och sura uppstötningar anses vara symtom på att magsäcksinnehåll flödar tillbaka upp genom övre magmunnen till matstrupen sk gastroesofageal refluxThis thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. A statement based on the evidence that reflux induced complications as esophagitis and

Genetic vaccines offer a treatment opportunity based upon successful gene delivery to specific immune cell modulators. Driving the process is the vector chosen for gene cargo packaging and subsequent delivery to antigen-presenting cells (APCs) capable of triggering an immune cascade. As such, the delivery process must successfully navigate a series of requirements and obstacles associated with the

Avhandlingens ämne är osannolika händelser i den realistiska romanen. Den övergripande idén är att realismen utmärks av att osannolika händelser hanteras utifrån ett dubbelt perspektiv: både som ett existentiellt och ett estetiskt bekymmer. Som ett existentiellt bekymmer representerar den narrativa fiktionsberättelsens osannolika händelser den ständigt närvarande möjligheten att en oförutsägbar ocThis thesis deals with improbable events in the realistic novel. The overarchingidea is that realism is distinguished by dealing with improbable events on thebasis of a double perspective: both as an existential and as an aesthetic problem.As an existential problem the improbable events of narrative fiction representthe constantly present possibility of an unexpected and unforeseen event suddenly

We analyzed human papillomavirus (HPV) prevalences during prevaccination and postvaccination periods to consider possible changes in nonvaccine HPV genotypes after introduction of vaccines that confer protection against 2 high-risk types, HPV16 and HPV18. Our meta-analysis included 9 studies with data for 13,886 girls and women ≤19 years of age and 23,340 women 20–24 years of age. We found evidenc

The latest Gaia data release enables us to accurately identify stars that are more luminous than would be expected on the basis of their spectral type and distance. During an investigation of the 329 best solar twin candidates uncovered among the spectra acquired by the GALAH survey, we identified 64 such overluminous stars. In order to investigate their exact composition, we developed a data-driv

Classical B lymphocyte activation is dependent on BCR cross-linking in combination with physical interaction with Th cells. Other B cell molecules that contribute to the activation are complement, cytokine, and TLRs recognizing specific pathogen-associated molecular patterns. Moraxella (Branhamella) catarrhalis is a common Gram-negative respiratory pathogen that induces proliferation in human IgD-

Popular Abstract in Swedish Strax efter andra världskriget bestod den judiska befolkningen i Sverige av cirka 13.000 personer. Det var mindre än en procent av landets dåvarande befolkning, men för den judiska befolkningen i Sverige var det en ökning med 65 procent jämfört med tiden före andra världskriget. Denna studie handlar om vilka historiska händelser som betonats hos den svenska judiska befoThe thesis deals with the queswtion of which historic events have been emphasised amog Jewish people in Sweden after the Second World War. The founding of Israel is the point of departure and the termins ad quem is ten years further. The basic source material for the study is Judisk krönika ("Jewish Cronicle"), a periodical which was launched in 1932. In the 1950s Judisk krönika assumed a special

In future radio systems, flexible coding and decoding architectures will be required. In case of the latter, implementing architectural flexibility with regard to low power issues is a challenging task. The flexible encoding platform in this paper is a first step toward this envisioned decoder. It generates a wide class of codes, starting with convolutional codes. As an extension to this, turbo co

Vaccination against the Human Papillomavirus (HPV) has recently been approved as a means to prevent cervical cancer. The Swedish Institute for Infectious Disease Control and the Swedish Society for Obstetrics & Gynecology arranged a consensus conference to discuss design of future cervical cancer prevention programs. Conclusions include that preventive programs should aim at eradication of onc

Latent autoimmune diabetes in adults (LADA) is a special form of diabetes that is clinically similar to type 2 diabetes but with positivity for pancreatic autoantibodies. The frequency of LADA patients among all patients diagnosed as type 2 varies between 6-50% in various populations. The frequency is higher in younger age groups. It is clear, however, that the frequency of autoimmune diabetes amo

Among the three recently described GB viruses (GBV-A, GBV-B, and GBV-C), only GBV-C has been linked to cryptogenic hepatitis in man. Because of the limited utility of currently available research tests to determine antibody response to GBV-C proteins, the prevalence of GBV-C RNA in human sera was studied using reverse transcription-polymerase chain reaction (RT-PCR). The prevalence of GBV-C is hig

The year 2022 marked the 10th anniversary of the course Critical Animal Studies: Animals in Society, Culture and the Media at the Department of Communication and Media at Lund University. As the first initiative of its kind in Sweden, the course explores the shifting roles and positions of non-human animals in today’s complex societies. It aims to equip students with analytical tools to critically

Mantle cell lymphoma (MCL) is dependent on a supportive tumor immune microenvironment (TIME) in which infiltration of CD163+ macrophages has a negative prognostic impact. This study explores how abundance and spatial localization of CD163+ cells are associated with the biology of MCL, using spatial multiomic investigations of tumor and infiltrating CD163+ and CD3+ cells. A total of 63 proteins wer

Löneavtal Unionen - Akademikerförbunden 2020-12-01-2020-04-30 LÖNEAVTAL Tjänstemän 2020-12-01–2023-04-30 Akademikerförbunden har i förhandlingarna företrätts av Akavia. Akavia uppträder under innevarande avtalsperiod som gemensam representant för Akademikerförbunden. Central förhandling, vanligtvis efter lokal förhandling enligt MBL §§ 10-12, begärs hos eller av Akavia oberoende av om berörd perso

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/randstad/dokument/2020_2023-loneavtal-unionen_-akademikerforbunden.pdf - 2026-07-10

Objectives: To identify serum and salivary gland proteomic biomarkers in primary Sjögren’s disease (SjD), evaluate their correlation with tissue inflammation, and relate findings to clinical, autoantibody, and genetic profiles. Methods: Paired salivary gland extracts and serum samples from patients with SjD (n = 81) and sicca controls (n = 19), and serum from larger Swedish (SjD n = 456; controls

Guidelines for the Ethical Review of Researchwithin the HT Faculties Guidelines for the Ethical Review of Research within the HT Faculties 2021 | ULF GÖRMAN | LUND UNIVERSITY © Ulf Görman Cover photo: Kennet Ruona Translation: Lena Olsson Second revised and enlarged edition of Lathund för etikprövning, Lund 2017. ISBN 978-91-89415-10-2 Preface Ethical considerations and guidelines are necessary if

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/policydok_planer/Ethical_review_2021_ENG_web.pdf - 2026-07-09

Centre for Mathemat ica l Sc iences Div i s ion of Mathematics and Numer ica l Analy s i s Course Analysis for Course MATB21 Analysis in Several Variables 1 Autumn 2022 Course Information Lecturer: Evgeniy Lokharu Teaching assistants: Jonathan Holmquist, Joakim Cronvall Number of students: 83 Examination Project: 55 students passed. Written examination: 42 students passed. - Ordinary examination 2

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/HT2022/MATB21HT22.pdf - 2026-07-09