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A critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part II: the meta-analyses.

We appraised the methodology, execution and quality of the five published meta-analyses that are based on the five randomized controlled trials (RCTs) which compared cardiotocography (CTG) +ST analysis to CTG. The meta-analyses contained errors, either created de novo in handling of original data, or from a failure to recognize essential differences among the RCTs, particularly in their inclusion

Evidensbaserad omvårdnad, sjukvård och kunskap

Research within nursing and medicine is moving at an increasing pace. This makes it difficult for the staff - involved with medical care to find the right path through all the new research and development. Working according to evidencebased procedures within both medicine and nursing means using in one’s work the recommendations which have been based on literature studies that have compiled, revie

A beta 40 Oligomers Identified as a Potential Biomarker for the Diagnosis of Alzheimer's Disease

Alzheimer's Disease (AD) is the most prevalent form of dementia worldwide, yet the development of therapeutics has been hampered by the absence of suitable biomarkers to diagnose the disease in its early stages prior to the formation of amyloid plaques and the occurrence of irreversible neuronal damage. Since oligomeric A beta species have been implicated in the pathophysiology of AD, we reasoned

Neutron decay width of one-particle resonant levels in deformed nuclei

The neutron partial decay width of one-particle resonant levels that are the bandhead states in odd-N deformed nuclei is estimated in the formalism with a real-energy variable, using the width of one-particle resonance calculated in terms of eigenphase. It is shown that because of the presence of various (lj) components in a given one-particle resonant level of deformed nuclei, the neutron decay w

The intestinal musculature of Derocheilocaris typica (Crustacea, Mystacocarida) - A different and unique pattern.

An ultrastructural study of the intestine of Derocheilocaris typica revealed an organization of the midgut musculature, which is unique in the Crustacea. This species unusual anal skeletomusculature has also not been seen before. The intestinal musculature of D. typica displays different patterns in the fore-, mid-, and hindgut. Around the foregut, eight pairs of dilator muscles complement a conti

Fabrication and Characterization of Ultra-Thin PIN Silicon Detectors for Counting the Passage of MeV Ions

This paper describes the fabrication and initial characterization of an ultra-thin silicon PIN detector using a new technique in silicon nanotechnology. In collaboration with the Nuclear Physics Division and the Lund Nano Lab at Lund University, we have developed and manufactured ultra thin Delta E-detectors for spectroscopic applications. The fabrication process has been carried out using a doubl

The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems-A review.

Poly(d,l-lactic-co-glycolic acid) (PLGA) is the most frequently used biodegradable polymer in the controlled release of encapsulated drugs. Understanding the release mechanisms, as well as which factors that affect drug release, is important in order to be able to modify drug release. Drug release from PLGA-based drug delivery systems is however complex. This review focuses on release mechanisms,

Pancreatic cancer tumorspheres are cancer stem-like cells with increased chemoresistance and reduced metabolic potential

Cancer stem cells are a population of slow-cycling cells within the tumour bulk, with self-renewal capacity that attracts interest as a therapeutic target. In highly heterogeneous tumours, like pancreatic ductal adenocarcinoma (PDAC) however, the characterisation of cancer stem cells has led to controversial results due to the lack of consensus on specific markers. Here we investigated the charact

New perspectives on the design of the buildings

The design of buildings has mainly focused on energy performances during the last decades however, it is also important to emphasize human needs and behaviour. Our research projects aim to advance knowledge of sustainability concepts in building design by investigating how buildings communicate with users towards sustainability, how are buildings perceived and used, and the roles of the individual

Heritable variation in thermal profiles is associated with reproductive success in the world's largest bird

Organisms inhabiting extreme thermal environments, such as desert birds, have evolved spectacular adaptations to thermoregulate during hot and cold conditions. However, our knowledge of selection for thermoregulation and the potential for evolutionary responses is limited, particularly for large organisms experiencing extreme temperature fluctuations. Here we use thermal imaging to quantify select

Ultrafast charge transfer dynamics in 2D covalent organic frameworks/Re-complex hybrid photocatalyst

Rhenium(I)-carbonyl-diimine complexes have emerged as promising photocatalysts for carbon dioxide reduction with covalent organic frameworks recognized as perfect sensitizers and scaffold support. Such Re complexes/covalent organic frameworks hybrid catalysts have demonstrated high carbon dioxide reduction activities but with strong excitation energy-dependence. In this paper, we rationalize this

Understanding Bachelorhood in Povertystricken and High Sex Ratio Settings : An Exploratory Study in Rural Shaanxi, China

Coupled with the social practice of female hypergamy, the male surplus within the never-married population means that today’s Chinese marriage market is extremely tight in particular for men from a rural background and the least privileged socio-economic categories. Drawing on quantitative data from a survey conducted in 2014–2015, this article sheds light on the situation of single men who are pa

Identification and characterization of in vitro expanded hematopoietic stem cells

Hematopoietic stem cells (HSCs) cultured outside the body are the fundamental component of a wide range of cellular and gene therapies. Recent efforts have achieved > 200-fold expansion of functional HSCs, but their molecular characterization has not been possible since the majority of cells are non-HSCs and single cell-initiated cultures have substantial clone-to-clone variability. Using the Fgd5

Management of Large Crowds in Underground Metro Stations

This report focuses on the issues associated with large occupant loads and counter-flows in underground metro stations. A basic case study is performed by simulating different countermeasures scenarios to investigate the implication that the countermeasures may have on the occupant load on the platform. The countermeasures investigated were modifications to the flow through ticket gates or escalat