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Recombinant adeno-associated virus (rAAV) is a mammalian virus that has been altered to be used as a gene delivery vehicle. Several changes to the viral genome have made them replication deficient so that this aspect of the viral infection cycle is under full control of the experimenter, while maintaining gene expression machinery. Over the last decades, rAAVs have become the gold standard for stu
In diffusion MRI (dMRI), images are sensitised to water diffusion by the application of magnetic field gradients. Cell membranes hinder the diffusional motion and thereby contribute to the contrast in dMRI. Thus, the diffusion of water molecules is used a probe of tissue microstructure. Data from dMRI is often analysed using diffusion tensor imaging (DTI), which yields image biomarkers that reflec
Sweden's ATMP ecosystem is rapidly expanding, solidifying its place as a key player in Europe. Currently ranking among the top three countries among the EU9 for identified therapeutic ATMP companies, Sweden's strategic investments are further reinforcing its leadership (MSC 2020). This includes ongoing initiatives to establish industrial-scale ATMP manufacturing capabilities, enhancing the country
Avdelningen Studieadministrativa system ansvarar bland annat för systemen Ladok, Lubas och SUNET Survey. Avdelningen arbetar med systemförvaltning samt systemadministration och ger utbildning och service till användarna.Study Administration Systems have responsibility for the Ladok, Lubas and SUNET Survey systems, among others. The unit works on system management and system administration and provides training and service to users. More information for staff: https://www.staff.lu.se/study-administration-systems
Syftar till att genom olika projekt bidra till ökad patientsäkerhet och till kvalitetsförbättringar inom sjukvården. Kunskap och erfarenheter utvecklas kring hur vårdgivare, både som individer och som sjukvårdssystem, kan erbjuda patienter en säkrare vård. Arbetet genomförs i interprofessionellt samarbete inom det medicinska/sjukvårdsområdet, men också i samverkan med andra vetenskapsområden, så Aims through different projects at improved Patient safety and Quality improvements within the healthcare system. Knowledge and experiences about how healthcare providers, both as individuals and as an organization, can provide a safer healthcare to patients are developed. This work is carried out through interprofessional collaboration within the medical/healthcare field, but also through collabo
Profilområdet utvecklar tvärvetenskapliga och gränsöverskridande hälsofrämjande strategier och metoder för proaktivt åldrande. Området fokuserar särskilt på kognitiv och muskuloskeletal hälsa som förutsättningar för aktivitet och delaktighet. Profilområdet ska utveckla metoder för att tidigt identifiera individer och grupper i riskzonen för ohälsa eller annan utsatthet med hjälp av ekonomiska, socThe profile area develops transdisciplinary health promotive strategies for proactive ageing. It focuses particularly on cognitive functions and musculoskeletal health as prerequisites for activity and participation. The profile area will develop methods for early identification of individuals and groups at risk of poor health or other vulnerabilities, using economic, social as well as biological
The Middle East in the Contemporary World (MECW) is a multi- and transdisciplinary strategic research area, hosted and supported by the Center for Middle Eastern Studies, comprising staff from five different faculties at Lund University.
Objective. Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP) is recommended over ASDAS based on erythrocyte sedimentation rate (ASDAS-ESR) to assess disease activity in axial spondyloarthritis (axSpA). Although ASDAS-CRP and ASDAS-ESR are not interchangeable, the same disease activity cut-offs are used for both. We aimed to estimate optimal ASDAS-ESR values corr
The Centre for East and South-East Asian Studies was created in 1997 as the result of a special government initiative. The Centre's task is the encouragement and furtherance of research in Sweden concerning modern East and South-East Asia, including the rapidly changing societies, developing economies and political institutions in the region. Building upon existing strengths at Lund University in
Endovascular repair has become the primary treatment option for abdominal aortic aneurysms over the past decade. The favorable results as well as technical evolution have led endovascular repair to include fenestrated and branched technology for complex juxtarenal, suprarenal, and thoracoabdominal aneurysms. These grafts are, however, extensively customized and patient tailored at present precludi
Abstract not available.
Expertis och forskningsinfrastruktur tillgänglig vid Lunds Lasercentrum (LLC), NanoLund och MAX IV möjliggör kunskap om ljusinducerade processer och funktionaliteter i material som tidigare har varit omöjliga för forskare att studera.
Inom profilområdet utnyttjas de senaste framstegen inom grundläggande forskning för att mäta och kontrollera ljus och material. Detta kommer att avsevärt förbätExpertise and research infrastructure available in NanoLund, Lund Laser Centre (LLC) and MAX IV allows scientists to gain insights into light-induced processes and functionalities of materials that were previously impossible to study.
The profile area will harness recent fundamental research advances in measuring and controlling light and materials. This substantially improves our understandi
LTH:s profilområde Livsmedel och bioteknik fokuserar på hållbar mat och biobaserade processer och produkter. Området arbetar för ett samhälle med minimalt miljöavtryck och noll utsläpp av växthusgaser, vilket resulterar i ett verkligt hållbart och cirkulärt samhälle.LTH Profile Area Food and Bio focus on sustainable, healthy, accessible food and bio-based processes and products. The area is working for a society with minimal environmental footprint and zero emission of greenhouse gases, resulting in a truly sustainable and circular society.
Genom att utveckla nya lasrar och fotonkällor samt skräddarsydda lösningar för tillämpad spektroskopi i olika miljöer, adresserar profilområdet samhällsutmaningar relaterade till klimatförändringar, miljöpåverkan och bekämpning av cancer och andra hot mot människors hälsa.By developing novel lasers and photon sources as well as tailored solutions suited for applied spectroscopy in different environments, the profile area addresses specific societal challenges related to climate change, environmental impact and combatting cancer and other threats to human health.
BACKGROUND One of the most challenging tasks of modern biology concerns the real-time tracking and quantification of mRNA expression in living cells. On this matter, a novel platform called SmartFlareTM has taken advantage of fluorophore-linked nanoconstructs for targeting RNA transcripts. Although fluorescence emission does not account for the spatial mRNA distribution, NanoFlare technology has g
BackgroundA novel non-invasive method for generation of pressure volume loops (PV-loops) using brachial blood pressure and cardiovascular magnetic resonance (CMR) imaging has recently been presented and validated (1). The non-invasive nature of this method enables calculation of PV-loops in large patient cohorts previously not feasible due to the need of invasive measurements.PurposeThe purpose of
