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Synucleinopthies are neurodegenerative diseases characterised by the formation of α-synuclein-rich intracellular inclusions in neurons and glia. Traditionally, animalmodels and immortalized cell lines have been used to investigate why and how theseinclusions form, and how they impact on cellular function. Recent advances incellular reprogramming and directed differentiation have enabled the genera

Pulmonary arterial hypertension (PAH) is a lethal condition where expansion of the vascular extracellular matrix contributes to increased pulmonary vascular resistance. Versican, a chondroitin sulfate proteoglycan, is known to accumulate in vascular lesions of PAH and hyaluronan and tenascin-C, binding partners of versican, are elevated in PAH. The specific distribution and localization of versica

Course Outline COSM23 - 2025 1 Course Outline COSM23: Contemporary Chinese Society 20 January to 21 March 2025 Course Convener Stefan Brehm Contact: stefan.brehm@ace.lu.se Teachers: Ning Ao, Stefan Brehm, Benjamin Davies, Martin Lavička, Gina Song Lopez, Nicholas Loubere, Marina Svensson, Jinyan Zeng Guest Lecturers: Christian Göbel, Rune Steenberg Place: All lectures and seminars will be held at

https://www.ace.lu.se/sites/ace.lu.se/files/2024-12/Course%20Outline%20COSM23%20-%202025.pdf - 2026-07-17

Uppsatsen har till syfte att beskriva och analysera vilken funktion förvaltningsrevisionen fyller i aktiemarknadsbolag som tillämpar Svensk kod för bolagsstyrning, samt ge förslag på hur förvaltningsrevisionen bör förändras i dessa bolag. Uppsatsen är till största del deduktiv då den tar sin utgångspunkt i teorier. Vidare grundas uppsatsen på en kvalitativ metod i form av semistrukturerade intervj

Sammanfattning Bakgrund: Stroke är en av de vanligaste folksjukdomarna i Sverige där 27 000 - 35 000 personer drabbas varje år. Stroke är ett samlingsnamn på vaskulära skador i hjärnan, vilka kan vara ischemiska eller till följd av blödning. En vanlig nedsättning hos personer drabbade av stroke är balansproblematik. Balansen är väsentlig för en självständig vardag och påverkar även den drabbades

I Sverige finns en väletablerad marknad för handel med barn för sexuella ändamål. Det är dock väldigt få anmälda brott som leder till åtal eller fällande dom. Detta visar på att barn som faller offer för människohandel inte innehar fullt rättsskydd. Den 1 januari 2020 trädde barnkonventionen i kraft som lag i Sverige, implementeringens primära syfte var att stärka barns rättsliga ställning. SyftetIn Sweden, there is a well-established market for child trafficking for sexual purposes. However, there are very few reported crimes that lead to prosecution or conviction. This shows that children who are victims to human trafficking do not have full legal protection. On January 1st, 2020, the Convention on the Rights of the Child entered into force as law in Sweden. The primary purpose of the im

Public procurement for innovation is a matter of using public demand to trigger innovation. Empirical studies have demonstrated that demand-based policy instruments can be considered to be a powerful tool in stimulating innovative processes among existing firms. However, the existing literature has not focused on the role this policy instrument can play in the promotion of (knowledge-intensive) en

The purpose of this study was to explore neuroretinal transplantation in a large animal model of severe retinitis pigmentosa and to establish graft development, long-term survival, graft-host integration, and effects on the host retina. Methods Rhodopsin transgenic pigs, aged 6 months, received in one eye a fetal full-thickness neuroretinal sheet in the subretinal space by means of vitrectomy and

– en rapport om lågkonjunkturens effekter Över 100 000 arbetslösa akademiker Över 100 000 arbetslösa akademiker - en rapport om lågkonjunkturens effekter Gilbert Fontana © Gilbert Fontana och Saco 2025 www.saco.se http://www.saco.se/ 2 Sammanfattning Sveriges svaga konjunktur märks allt tydligare på arbetsmarknaden. Sedan sommaren 2023 har arbetslösheten gradvis ökat, även bland högutbildade som v

https://www.saco.se/contentassets/a127f8576f9a4598b1ba62279526380b/over-100-000-arbetslosa-akademiker---en-rapport-om-lagkonjunkturens-effekter.pdf - 2026-07-17

In this work, we present an actors-to-hardware design flow where applications are described as networks of actors and compiled to hardware. Specifically, we use the CAL actor language to describe these applications. CAL has previously been used to specify applications such as the MPEG-RVC decoder and is well suited for compilation to hardware. A key limitation of CAL is that the applications descr

This chapter examines elite polarisation as a challenge to governance in parliamentary democracies. We emphasise the distinction between ideological polarisation based on substantive policy disagreements from affective polarisation, characterised by identity-based animosity that creates barriers to cooperation even when policy compromise might otherwise be possible. While parliamentary regimes hav

This position paper examines the growing dominance of health economics in Swedish healthcare governance and argues that its elevated epistemic authority produces significant risks for the sustainability and ethical integrity of care systems. Drawing on feminist theories of care and critical political economy, the paper interrogates the assumption that care can be adequately represented, valued, or

Syfte: Syftet med uppsatsen är att beskriva och analysera den företagsinterna implementeringsprocessen rörande Svensk kod för bolagsstyrning i några företag, diskutera inställningen till Koden och dess självregleringsprincip, samt söka samband mellan dessa beståndsdelar och hur väl företagen följer bestämmelserna. Metod: Vår kvalitativa undersökning baseras på en tidigare utförd kvantitativ studie

A multi-lane traffic flow model based on stochastic noise driven dynamics is introduced and analyzed. The model employs conservative anisotropic Arrhenius spin-exchange (surfacediffusion) dynamics. We generate an asymmetric simple exclusion process to model vehicleinteractions. Vehicles react and advance based on the energy profile of their surrounding trafficthrough a novel look-ahead asymmetric

Introduction: Deliberate self-harm (DSH) is a common symptom in psychiatric disorders. It is a cross-diagnostic symptom, although it has mainly been associated with borderline personality disorder (BPD). Research has suggested an association between DSH and deficits in executive functioning. The main aim of the current study was to assess three specific aspects of executive functioning (EF) (worki

Flexible colonoscopy remains the prime mean of screening for colorectal cancer (CRC) and the gold standard of all population-based screening pathways around the world. Almost 60% of CRC deaths could be prevented with screening. However, colonoscopy attendance rates are affected by discomfort, fear of pain and embarrassment or loss of control during the procedure. Moreover, the emergence and global