Filetype
The goal of this research is to use hematopoietic cells as vehicles for targeting transgenic immunomodulators to the inflammatory sites. The work presented was focused on the anti-inflammatory soluble TNF receptor. A transmembrane soluble TNF receptor (sTNFR1) construct was expressed in hematopoietic cell lines. ER export was facilitated by addition of a transmembrane (tm) sequence, and constituti
The aim of the present study was to evaluate the risk for vascular morbidity or death and retinopathy in relation to urinary albumin concentration. To that end, we performed a 5-year follow-up study of all type 2 diabetic patients attending the outpatient-clinic. A total of 444 (98.4%) out of 451 adult patients initially studied were evaluated for the degree of retinopathy and levels of HbA1c bloo
BACKGROUND: A previous study has shown that pentoxifylline in combination with vitamin E can reverse radiation-induced fibrosis. The aim of the present study is to investigate if the same drugs could prevent radiation-induced side-effects in women with breast cancer. PATIENTS AND METHODS: A randomised, placebo-controlled, double-blind, parallel group trial was performed. Women with breast cancer w
A search is presented for direct top squark pair production using events with at least two leptons including a same-flavour opposite-sign pair with invariant mass consistent with the boson mass, jets tagged as originating from -quarks and missing transverse momentum. The analysis is performed with proton-proton collision data at collected with the ATLAS detector at the LHC in 2012 corresponding to
Objective. New proposed definitions of chronic kidney disease necessitate the development and use of simple and accurate methods for estimating glomerular filtration rate (GFR). Plasma cystatin C has been shown to be a more reliable GFR marker than creatinine and formulae for estimating GFR have been reported. The purpose of this study was to validate a cystatin C-based GFR prediction equation in
Background. Randomized trials have shown that icodextrin reduces the volume of extra-cellular fluid (ECFv) with variable effects on residual renal function. To explore this fluid shift and its possible mechanisms in more detail, prospectively collected data from one such trial, including measures of inflammation (C-reactive protein, tumor necrosis factor-a, albumin and low and high molecular weigh
The results of a search for pair production of light top squarks are presented, using 4.7 fb(-1) of root s = 7 TeV proton-proton collisions collected with the ATLAS detector at the Large Hadron Collider. This search targets top squarks with masses similar to, or lighter than, the top quark mass. Final states containing exclusively one or two leptons (e, mu), large missing transverse momentum, ligh
Shredder residues of end-of-life vehicles and white goods are a complex waste stream, which nowadays most often is disposed of at industrial landfills. This paper describes the most important findings concerning the complex composition of the landfill leachate and its on-site, year-round treatment under cold-climate conditions. A 3-year investigation has confirmed that concentrations of different
This Letter presents the results of a direct search with the ATLAS detector at the LHC for a Standard Model Higgs boson of mass 110 <= m(H) <= 130 GeV produced in association with a W or Z boson and decaying to b (b) over bar. Three decay channels are considered: ZH -> l(+)l(-)b (b) over bar, WH -> lvbb (b) over bar and ZH -> v (v) over bar(b) over bar where l corresponds to an electron or a muon.
Mesenchymal stroma cells (MSCs) have a high potential for novel cell therapy approaches in clinical transplantation. Commonly used bone marrow-derived MSCs (BM-MSCs), however, have a restricted proliferative capacity and cultures are difficult to standardize. Recently developed human embryonic stem cell-derived mesenchymal stroma cells (hES-MSCs) might represent an alternative and unlimited source
Background: Globalization is a phenomenon which has been around since the mid- 19th century, influencing companies to either expand existing markets or entering new markets, to seek new profits. For companies with a global supply chain, the total supply chain cost is a vital factor. It is of high importance to reduce the costs in the supply chain, as lower costs will increase the profit. The case
This paper aims to examine the arguments proposed by the Obama administration regarding a U.S. military intervention in Syria due to the use of chemical weapons by the Syrian regime in 2013. During his presidency, Obama stated that the He draws a ‘red line’ at the use of chemical weapons against civilians, but the threat proved to be empty a year later when thousands of people were killed in a che
In light of the growing “coherence” between humanitarianism and political actions in today’s world, does aid remain conducive to socio-economic improvement, or does it inhibit the ushering of much needed change? In the context of this study, the besieged population of Gaza organized large weekly demonstrations known as the Great Return March (2018-2020) to demand their basic political, economic an
Although the Bangsamoro peace-process in the Southern Philippines has been valued for its gender commitments and potential to build just and sustainable peace, discrimination of the Bangsamoro peoples and other minorities prevail. This thesis uncovers how women peace advocates understand social justice and its remedies in the context of the Bangsamoro peace-process, and which opportunities they ha
Sinusitis is a common disease caused by a virus or bacteria, with 84% to 91% of cases caused by a viral pathogen. However, physicians prescribe antibiotics for this disease in 85% of all cases. GPX Medical is a company working on the development of a medical device which, by means of absorption spectroscopy, can determine whether the disease is caused by virus or bacteria supporting, thus, the doc
This essay explores four English teachers’ views on their methods of teaching vocabulary, as well as the incorporation of translanguaging in their teaching of English vocabulary. The study investigates what the teachers’ preferred methods of teaching vocabulary are and whether they rely more on implicit or explicit vocabulary teaching. Furthermore, the study explores if the participating teachers
The study field of the thesis is regional integration in Africa. The focus is set on the African Union (AU) and its main programme for promoting democracy on the continent, the New Partnership for Africa´s Development (NEPAD). By applying two theories, one on democratization through regional organizations and the other on hidden agendas within them, the thesis makes an assessment on the work for d
Aim: To investigate the effect of general anaesthesia on the TCI-dosage, the depth of anaesthesia and the need for hemodynamic treatment. A comparison between general anaesthesia (GA) alone and general anaesthesia combined with epidural anaesthesia (GA+EDA). Background: There are some uncertainties in the literature whether epidural anaesthesia has any effect on general anaesthesia governed by Ta
