Filetype
Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly
The aim of this study was to evaluate the equations for calculating the clothing area factor (fcl) used in the standards based on data sets of clothing ensembles, that are meant to provide thermal comfort over a wide range of climatic conditions from hot summer days to extremely cold winter. Over 10 equations for fcl calculations were selected from the international standards and the literature. A
Att insjukna i en reumatisk ledsjukdom innebär betydande förändringar i livet, särskilt när det sker under barndomen eller ungdomen. Vår forskning omfattar flera reumatiska och inflammatoriska tillstånd, med särskilt fokus på juvenil idiopatisk artrit (JIA), men även andra sjukdomar som Kawasakis sjukdom och MIS-C (hyperinflammation efter COVID-19-infektion). Vi bedriver både klinisk- och laboratoBeing diagnosed with a rheumatic disease entails significant life changes, especially when it occurs during childhood or adolescence. Our research encompasses several rheumatic and inflammatory conditions, with a particular focus on juvenile idiopathic arthritis (JIA), but also other diseases such as Kawasaki's disease and MIS-C (hyperinflammation following COVID-19 infection). We conduct both cli
The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.
Background Mental health interventions should demonstrate an effect on patients' functioning as well as his/her needs, in particular on unmet needs whose assessment depends on the perspective of either the patient or the clinician. However, individual met and unmet needs appear to change over time, qualitatively and quantitatively, raising questions about their sensitivity to change and about the
