Search results

On October 9, 2023, Harvard University Professor Claudia Goldin received the Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel, a landmark achievement that not only celebrates her outstanding contributions but also highlights the profound impact an economist can have on society.

Obesity and type 2 diabetes are increasing at alarming rates worldwide, presenting significant public health challenges. A key player in these conditions is GLUT4, a protein that helps transports glucose into cells in response to insulin. Proper function of GLUT4 is crucial for maintaining healthy blood sugar levels and overall metabolic health.To address this, in this thesis I have explored the m

This work demonstrates the utility of dual-arm robots with dual-wrist force-torque sensors in manipulating a Deformable Linear Object (DLO) within an unknown environment that imposes constraints on the DLO’s movement through contacts and fixtures. We propose a strategy to estimate the pose of unknown environmental contacts encountered during the manipulation of a DLO, classifying the induced const

This paper derives theoretical results for adaptive bias in Doherty amplifiers and presents the design and measurements of an integrated adaptive bias circuit tailored for high peak-to-average high bandwidth signals. Fundamental equations for output power, impedance, and efficiency of the complete Doherty amplifier are derived. Even with ideal transistor models, the Doherty amplifier is fundamenta

This article focuses on citizens’ experiences of enablers of- and barriers to obtaining digital citizenship. E-applications for social assistance are used as an exemplar. In Sweden, as in many countries, there is political pressure on welfare services to become more digitalized, and to offer different kinds of self-service technology such as e-applications. Even if the goals of implementing these

This thesis addresses the critical issue of design and development of products like production machines for SMEs and rural communities as an essential capability to foster local technology development within the innovation systems of Latin America. What is studied and discussed in this thesis is the pre-requisites for effective application of design and development methods, like design thinking

Non-invasive biological samples benefit studies that investigate rare, elusive, endangered, or dangerous species. Integrating genomic techniques that use non-invasive biological sampling with advances in computational approaches can benefit and inform wildlife conservation and management. Here, we used non-invasive fecal DNA samples to generate low- to medium-coverage genomes (e.g., >90% of the co

AIMS: Biomarkers associated with asymptomatic ventricular dysfunction might improve risk stratification and identify pathways leading to heart failure (HF). We explored the association between proteomic biomarkers and left ventricular hypertrophy (LVH), diastolic dysfunction (DD) and incident HF in three population-based cohorts.METHODS AND RESULTS: A chip was used to measure 92 protein biomarkers

Quality control of stabilized dredged sediment (DS) presents significant challenges due to its high-water content. Nowadays, many in-situ and laboratory tests have been used to evaluate the quality of treated DS, and the dominant method is 28-day unconfined compressive strength that can be done on undisturbed samples from the field and the laboratory. Due to the waiting period to get results from

Changes in biomarker levels of Alzheimer’s disease (AD) reflect underlying pathophysiological changes in the brain and can provide evidence of direct and downstream treatment effects linked to disease modification. Recent results from clinical trials of anti–amyloid β (Aβ) treatments have raised the question of how to best characterize the relationship between AD biomarkers and clinical endpoints.

Multi-functional molecules with spirocyclic acetal structures have recently emerged as attractive monomers to prepare high-performance polymers, which may subsequently be de-polymerized and recycled under specific physicochemical conditions. Spirocyclic acetal structures can be formed by condensation of a suitable aldehyde or ketone with a polyol so that the functionalities necessary for the polym

Since the last edition of this book (2014), progress has been astonishing in all areas of Natural Language Processing, with recent achievements in Text Generation that spurred a media interest going beyond the traditional academic circles. Text Processing has meanwhile become a mainstream industrial tool that is used, to various extents, by countless companies. As such, a revision of this book was

As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their technical setup from a conventional TBI technique to multi-isocenter conformal arc therapy techniques such as Volumetric Modulated Arc Therapy (

Purpose: Prior research has proposed a number of scales measuring the customer experience (CX), which tend to conceptualize and operationalize CX differently, raising potential confusion among researchers (e.g. regarding which scale to use). Addressing this issue, this article conducts a systematic review to inventorize key CX scales and assess their theoretical rigor, with a focus on the identifi

Objectives: To perform a descriptive analysis of a series of patients with recurrent macroscopic haematuria after a primary standard evaluation including computed tomography urography (CTU) and cystoscopy negative for urinary bladder cancer (UBC) and upper tract urothelial cancer (UTUC) and to identify potential factors associated with occurrence of recurrent macroscopic haematuria. Methods: All p

Climate change has diverse effects on the planet’s environment, including changes and shifts in the distribution and abundance of species. In this paper, we present a robust prediction ensemble algorithm for the current and future species distribution of Aegilops tauschii. Four modeling approaches were trained using various environmental variables (bioclimatic and soil variables) to accurately pre

Protein tyrosine phosphatases (PTPs) possess a conserved mobile catalytic loop, the WPD-loop, which brings an aspartic acid into the active site where it acts as an acid/base catalyst. Prior experimental and computational studies, focused on the human enzyme PTP1B and the PTP from Yersinia pestis, YopH, suggested that loop conformational dynamics are important in regulating both catalysis and evol