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Cell Division is a new, open access, peer-reviewed online journal that publishes cutting-edge articles, commentaries and reviews on all exciting aspects of cell cycle control in eukaryotes. A major goal of this new journal is to publish timely and significant studies on the aberrations of the cell cycle network that occur in cancer and other diseases.
MAK (male germ cell-associated protein kinase) and MRK/ICK (MAK-related kinase/intestinal cell kinase) are human homologs of Ime2p in Saccharomyces cerevisiae and of Mde3 and Pit1 in Schizosaccharomyces pombe and are similar to human cyclin-dependent kinase 2 (CDK2) and extracellular signal-regulated kinase 2 (ERK2). MAK and MRK require dual phosphorylation in a TDY motif catalyzed by an unidentif
Background: Chronic pain is a common comorbid complaint in traumatized refugees seeking treatment for posttraumatic stress disorder (PTSD) and depression. However, the effect of comorbid pain on treatment remains under investigated. Objective: To investigate whether pre-treatment pain (severity/interference) predicts outcomes in a multimodal treatment targeting PTSD, depression, anxiety, somatic c
AimDecades of research confirm that children and adolescents in out‐of‐home care (foster family, residential care) have much greater health care needs than their peers. A systematic literature review was conducted to evaluate organisational health care models for this vulnerable group.MethodsA systematic literature search was undertaken of the following databases: Academic Search Elite, CENTRAL, C
Background: In patients on hemodialysis with end-stage renal disease there is an increasing interest in measuring both residual renal function (RRF) and quantity and quality of dialysis because insufficient dialysis gives higher mortality. For that purpose we have measured clearances of two urographic iodine (I) contrast media (CM) with different molecular masses (iohexol 821 u and iodixanol 1,550
Sweden and Japan are developed welfare countries facing serious societal and public health challenges due to demographic ageing. The objective of the present study was to provide a background to environmental challenges in the home, related to demographic ageing. Specific aims were to compare: 1) demography and household composition 2) physical housing stocks 3) indoor accidents and 4) housing ada
BACKGROUND: Germinal matrix-intraventricular haemorrhage (GMH-IVH) remains a substantial issue in neonatal intensive care units worldwide. Current therapies to prevent or treat GMH-IVH are limited. Stem cell-based therapies offer a potential therapeutic approach to repair, restore, and/or regenerate injured brain tissue. These preclinical findings have now culminated in ongoing human neonatal stud
Hydrogen peroxide treatment is a cost-effective and simple method to improve the bioactivity of titanium implants. In this study, the effects of chloride ion concentration and temperature of hydrogen peroxide on the surface treatment of titanium were investigated using X-ray diffractometry (XRD), Field Emission-Scanning Electron Microscopy (FESEM), and tests in order to determine wettability and a
This article offers an analysis of three popular Swedish handbooks for new parents, written by authors in the “media class.” In these texts breastfeeding as a gendered, embodied practice collides with the Swedish ideal of gender-equal parenting. The analysis explores the various ways that gendered bodies, gendered (parental) rights, and gender equality figure in the handbooks, drawing upon feminis
Yangia sp. ND199 is a moderately halophilic bacterium isolated from mangrove samples in Northern Vietnam, which was earlier reported to grow on several sugars and glycerol to accumulate poly(hydroxyalkanoates) (PHA). In this study, the potential of the bacterium for co-production of exopolysaccharides (EPS) and PHA was investigated. Genome sequence analysis of the closely related Yangia sp. CCB-M3
STUDY DESIGN: We retrospectively analyzed Spinal Instability Neoplastic Score (SINS) in 110 patients with prostate cancer operated for metastatic spinal cord compression (MSCC). OBJECTIVE: We aimed to investigate the association between SINS and clinical outcomes after surgery for MSCC in patients with prostate cancer. SUMMARY OF BACKGROUND DATA: The SINS is a useful tool for assessing tumor-relat
This paper investigates how multiple in-cycle closed-loop combustion controllers can be integrated for a seamless operation under a wide-range of operating conditions. The stochastic cyclic variations of the combustion can be successfully compensated by the adjustment of the fuel injection pulses within the same cycle. The feedback information and controllability obtained relies on the different o
In Bolivia climate change and anthropogenic activities such as extensive agriculture, industries and urbanization have increased the groundwater demand and extraction, which is leading to severe stress on groundwater resources in several regions of Bolivia. This research aims to present an overview of different geophysical surveys performed in Valle Alto (central Bolivia), in particular in the Pun
Streptococcus pneumoniae (pneumococcus) resides asymptomatically in the nasopharynx but can progress from benign colonizer to lethal pulmonary or systemic pathogen. Both viral infection and aging are risk factors for serious pneumococcal infections. Previous work established a murine model that featured the movement of pneumococcus from the nasopharynx to the lung upon nasopharyngeal inoculation w
Despite the fact that the laser-cooling method is a well-established technique to obtain ultracold neutral atoms and atomic cations, it has rarely if ever been applied to atomic anions due to the lack of suitable electric-dipole transitions. Efforts of more than a decade have until recently only resulted in La- as a promising anion candidate for laser cooling, but our previous work [Tang et al., P
Solar radiation plays a pivotal role in the energy balance at the Earth's surface, evaporation, snow melting, water requirements of plants, and hydrological control of catchments. In this work, performance of ERA-Interim (a reanalysis dataset) was examined to estimate solar radiation at Ahvaz, BandarAbbas, and Kermanshah weather stations representing the even spatial distribution over Iran using e
BackgroundThe efficacy of technology-delivered cognitive-behavioral therapy (tCBT) for pediatric anxiety disorders (ADs) is uncertain as no meta-analysis has examined outcomes in trials that used structured diagnostic assessments at pre- and posttreatment.MethodsWe carried out a systematic review and meta-analysis of randomized controlled trials (RCTs) of tCBT for pediatric ADs that included parti
Microscopy analysis of tumour samples is commonly performed on fixed, thinly sectioned and protein-labelled tissues. However, these examinations do not reveal the intricate three-dimensional structures of tumours, nor enable the detection of aberrant transcripts. Here, we report a method, which we name DIIFCO (for diagnosing in situ immunofluorescence-labelled cleared oncosamples), for the multimo
A novel kind of Z-scheme ternary heterojunctions phosphate-doped BiVO4/graphene quantum dots/P-doped g-C3N4 (BVP/GQDs/PCN) were fabricated for the visible light degradation of norfloxacin (NOR), a typical antibiotic. Compared with binary type-II heterojunction phosphate-doped BiVO4/PCN (BVP/PCN), Z-scheme BVP/GQDs/PCN exhibited promoted interfacial charge transfer efficiency and broadened visible
Background: Long-term follow-up (LTFU) care for childhood, adolescent, and young adult (CAYA) cancer survivors is essential to preserve health and quality of life (QoL). Evidence-based guidelines are needed to inform optimal surveillance strategies, but many topics are yet to be addressed by the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG). Therefore, the Pan
