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Earth system models (ESMs) are key tools for providing climate projections under different scenarios of human-induced forcing. ESMs include a large number of additional processes and feedbacks such as biogeochemical cycles that traditional physical climate models do not consider. Yet, some processes such as cloud dynamics and ecosystem functional response still have fairly high uncertainties. In t

The emerging concept of sustainable welfare attempts to integrate environmental sustainability and social welfare research. Oriented at a mid-term re-embedding of Western production and consumption norms into planetary limits, it suggests the development of “eco-social” policies in the rich countries. In this theoretical context, this article empirically investigates the relationships between atti

Accurate and efficient measurement techniques are needed for exposure assessment of 5G portable devices---which are expected to utilize frequencies beyond 6 GHz---with respect to the radio frequency electromagnetic field exposure limits. Above 6 GHz, these limits are expressed in terms of the incident power density, thus requiring that the electromagnetic fields need to be evaluated with high prec

Second primary cancers (SPCs) are becoming a common cancer entity, which may interfere with survival in relatively benign first primary cancers. We examined the hypothesis that immune dysfunction may contribute to SPCs by assessing SPCs associated with known immune responsive skin cancers, invasive and in situ squamous cell carcinoma, Kaposi sarcoma, and Merkel cell carcinoma. Cancers were identif

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of caffeine compared to aminophylline or theophylline in preterm infants at risk of apnea, with apnea, or in the peri-extubation phase.

Treatment of chronic osteomyelitis by radical debridement and filling of the dead space with antibiotic containing calcium sulphate/hydroxyapatite (CaS/HA) bone substitute has shown excellent long-term outcomes. However, in extensive infections, sessile bacteria may remain in bone cells or soft tissues protected by biofilm leading to recurrences. The primary aim of this study was to evaluate if sy

Universities are increasingly being seen as a positive vehicle for territorial development and regional transformation, with an important role in enhancing Social, Economic and Sustainable Development of territories. The world’s sustainability challenges are listed in the United Nation’s Agenda 2030, that includes Higher Education Institutions (HEIs) as actors that can work in partnership with oth

The advent and popularity of shared electric scooters in many urban areas worldwide offer new opportunities and challenges to be addressed by the research community, especially as far as safety and accessibility issues are concerned. This paper proposes a methodology, based on geofencing technology (i.e., virtual geographic boundaries) to define in which urban areas the speed of shared electric sc

Background. We investigated how varying the treatment margin and applying hippocampal sparing and proton therapy impact the risk of neurocognitive impairment in pediatric medulloblastoma patients compared with current standard 3D conformal radiotherapy. Methods. We included 17 pediatric medulloblastoma patients to represent the variability in tumor location relative to the hippocampal region. Trea

This study investigated the dosimetric impact of uncompensated motion and motion compensation with dynamic multileaf collimator (DMLC) tracking for prostate intensity modulated arc therapy. Two treatment approaches were investigated; a conventional approach with a uniform radiation dose to the target volume and an intraprostatic lesion (IPL) boosted approach with an increased dose to a subvolume o

Responsible internationalization has become an increasingly used term to promote relationship building in a world which is increasingly shaped by the growing impact of global challenges and geopolitical competition. Amidst these changing global conditions researchers and universities have started to learn that they need to adhere to an expanded set of norms related to the research endeavor. Today

BOADICEA is a comprehensive risk prediction model for breast and/or ovarian cancer (BC/OC) and for carrying pathogenic variants (PVs) in cancer susceptibility genes. In addition to BRCA1 and BRCA2, BOADICEA version 6 includes PALB2, CHEK2, ATM, BARD1, RAD51C and RAD51D. To validate its predictions for these genes, we conducted a retrospective study including 2033 individuals counselled at clinical

The sixth volume in the Interdisciplinary European Studies assesses the changes that are taking place in the EU’s policies, institutions, and political structures. On the eve of a new chapter of European integration in the dark shadow of the war in Ukraine, it is high time to assess the changes that have taken place in recent time and consider whether current developments are taking the EU on the

The majority of spatial data users are inexperienced in spatial information science. This group of users cannot analyze spatial data and produce the required information. Therefore, the availability of mechanisms and applications for automatic and interoperable spatial data processing and information extraction is necessary. Generalization is one of the main geoprocesses, which is widely used. The

Diffusion MRI is a non-invasive imaging technique used to study the microstructural properties of biological tissues by observing the self-diffusion of water molecules. Traditional diffusion MRI methods, based on the pulsed gradient spin-echo sequence, employ magnetic field gradients to encode information about translational motion. However, this approach combines various aspects of diffusion, suc