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The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research using various approaches including genetics, imaging, clinical and animal models has advanced our knowledge regarding NPDs, we still lack basic knowledge regarding the underlying pathophysiological mechanisms. Moreover
Background: Newborn infants undergoing therapeutic hypothermia (TH) are exposed to multiple painful and stressful procedures. The aim of this systematic review was to assess benefits and harms of pharmacological and non-pharmacological interventions for the management of pain and sedation in newborn infants undergoing TH for hypoxic-ischemic encephalopathy. Methods: We included randomized and obse
Exposure to elemental mercury (Hg) vapour results in an accumulation of Hg in the pituitary, the thyroid, and the testis. In this study, basal serum concentrations of pituitary hormones (thyrotrophin (TSH), prolactin (PRL), follicle stimulating hormone (FSH), and luteinising hormone (LH] or their response after administration of thyrotrophin and gonadotrophin releasing hormones did not differ betw
This work presented the working scheme developed and used in order to conduct multiple daylight simulations for distinct rooms in a wide range of apartment buildings within the urban grid. The objective was to generate 3D models of the rooms under study and their urban surroundings, and to obtain the corresponding illuminance files and geometry information in a time-efficient, automated manner. Th
Disease gene identification is still a challenge despite modern high-throughput methods. Many diseases are very rare or lethal and thus cannot be investigated with traditional methods. Several in silico methods have been developed but they have some limitations. We introduce a new method that combines information about protein-interaction network properties and Gene Ontology terms. Genes with high
Sclerosing injections under ultrasonographic guidance is a new method of treatment for persistent pain in Achilles tendinosis. Good results, even superior to those of surgery, have been described. We report the outcome of 25 patients with midportion tendinosis receiving sclerosing treatment. Twenty-eight consecutive patients (29 tendons) with ultrasonographical findings of midportion tendinosis ex
This paper presents a technique to reduce the noise figure of a passive mixer-first receiver front-end. By using lower than 50Ω switch resistance in the current-mode passive mixer and introducing a positive feedback from baseband to the RF-input, it can be well matched close to fLO while achieving a noise figure below 3dB, which is otherwise a fundamental limit. A quadrature front-end prototype fo
From newly obtained high-resolution, high signal-to-noise ratio spectra the abundances of the elements La and Eu have been determined over the stellar metallicity range -3<[Fe/H]<+0.3 in 159 giant and dwarf stars. Lanthanum is predominantly made by the s-process in the solar system, while Eu owes most of its solar system abundance to the r-process. The changing ratio of these elements in stars ove
The aim of this study was to gain knowledge about leadership style and its relation to coworker's wellbeing. Of special interest was to find the best predictor variable of wellbeing. A further aim was to study differences between males and females in organizational commitment and wellbeing. A questionnaire was distributed to 100 employees in Telia, a Swedish telecom company. 62 questionnaires
In this thesis, the Wideband Sparse Exponential Mode Analysis (WSEMA) estimator is introduced. It combines two recently developed techniques, the wideband dictionary and the Sparse Exponential Mode Analysis (SEMA) to make for an efficient estimator. WSEMA estimates the parameters of decaying sinusoids, without a priori-information about the number of modes present in the signal. WSEMA works with a
As the negative environmental impacts of contemporary agriculture become still more evident and widespread, the question of how to feed future generations while preserving the vital stability of the planet’s environment is more urgent than ever. Major institutions are targeting the environmental sustainability of agriculture, internationally as well as in Brazil. Brazil is one of the largest agric
