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An increasing incidence of testicular cancer has been reported from several western countries during the last decades. According to current hypothesis testicular cancer is initiated during the foetal period and exposure to endocrine disruptors such as some persistent organic pollutants has been of concern. We have previously reported the results for concentrations of polychlorinated biphenyls (PCB
Summary: We studied the risk for hip fracture before and after total knee replacement (TKR) in the entire population in Sweden. Women and men had a low risk for hip fracture before TKR but an increased risk the first year after TKR. Purpose: It is known that osteoarthritis is associated with high bone mass. We therefore studied the risk of hip fracture before and after total knee replacement (TKR)
Context. Stellar evolution models predict that internal mixing should cause some sodium overabundance at the surface of red giants more massive than ~1.5-2.0 M⊙. The surface aluminium abundance should not be affected. Nevertheless, observational results disagree about the presence and/or the degree of Na and Al overabundances. In addition, Galactic chemical evolution models adopting different stel
Open access is a well-known externality problem in fisheries causing excess capacity and overfishing. Due to global warming, externality problems from CO2 emissions have gained increased interest. With two externality problems, a first-best optimum can be achieved by using two regulatory instruments. However, solving the open-access externality problem also affects CO2 emissions. By using a bio-ec
The Value of a Statistical Life (VSL) is a widely used measure of the value of mortality risk reduction. Since VSL should reflect preferences and attitudes to risk, there are reasons to believe that it varies depending on the type of risk involved. It has been argued that cancer should be considered a “dread disease”, which supports the use of a “cancer premium”. The objective of this study is to
Health care professionals frequently describe performance management and monitoring of efficiency and quality measures for external accountability as an administrative burden with limited benefits. Professionals argue that they are subject to too tight control that signals distrust, limits professional autonomy and ultimately decreases their motivation to perform. At worst, poorly incen
Many workers are exposed to heat stress that can be exacerbated by the type of clothing they wear. The resulted heat strain can lead to short or long-term heat-related disorders. This study aimed to measure clothing properties of sugarcane field workers and evaluate the heat strain by an international standard, predicted heat strain model (PHS). The clothing thermal insulation and evaporative resi
This paper examines a piece of headgear, usually referred to in modern literature asa Phrygian or Persian cap, but variously described as tiara, kurbasia or kidaris/kitaris in the ancient sources. According to Greek texts only the Persian king had theright to wear the headgear in an upright position, usually referred to as tiara orthé.The cap was part of the so-called Median riding dress, and was This paper examines a piece ofheadgear, usually referred to in modern literature as a Phrygian or Persian cap, but variously described astiara, kurbasiaor kidaris/kitarisin the ancient sources. According to Greek texts only the Persian king had the right to wear the headgearin an upright position, usually referred to as tiara orthé. The cap was part of the so-called Median riding
This thesis is based on work done by the author on the development of plasma-based electron accelerators driven by ultra-intense laser pulses and dense electron bunches. Plasma based accelerators have several benefits, such as accelerating fields around 1000 times stronger than in “conventional” radio-frequency accelerators, which can allow for shrinking the overall footprint of the accelerator. T
The pig is becoming an increasingly used non-primate model in experimental studies of human retinal diseases and disorders. The anatomy, size, and vasculature of the porcine eye and retina closely resemble the human counterparts, which allows for application of standard instrumentation and diagnostics used in the clinic. Despite the many reports demonstrating immunohistochemistry as a useful metho
Aims Genetic testing is needed for the formal diagnosis of maturity-onset diabetes of the young (MODY), but this is not widely available. If any MODY biomarkers were known, these could possibly be used as an alternative. Hepatocyte nuclear factor (HNF)-1alpha and HNF-4alpha regulate transcription of genes encoding complement 5 (C5), complement 8 (C8) and transthyretin (TTR), suggesting that these
Meta-analyses are vital for synthesizing evidence in medical research, but conflicts of interest can introduce research bias, undermining the reliability of the synthesized findings. This paper proposes a new robust Bayesian meta-analysis model. The model inflates uncertainty of low-quality studies and incorporates a bias term for studies subject to conflicts of interest. Using a random-effects mo
Two electrotechnologies: pulsed electric fields (PEF) and moderate electric field (MEF) in combination with vacuum impregnation of glycerol as cryoprotectant were used to increase the freezing tolerance of rocket leaves. Rocket leaves were treated with PEF using a nominal field strength of 1200 V/cm or MEF at different combinations of voltage and frequency. Leaves were then immersed in a glycerol
There has been an increased interest in the study of underlying autonomic correlates of emotions. This study tests the hypothesis that high levels of high-frequency heart rate variability (HF HRV) are associated with positive emotions. In addition, we hypothesize that this association will differ according to the type of positive emotion. Also, based on recent findings, we tested the hypothesis th
Background: Pelvic exenteration for locally advanced rectal cancer (LARC) and locally recurrent rectal cancer (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes of exenteration over time.Methods: This was a multicentre retrospective study of patients who underwent exenteration for LARC and LRRC between 2004 and 2015. Su
Microplastics are increasingly recognized as a pervasive pollutant in both aquatic and terrestrial environments, raising pressing concerns about their ecological impacts and implications for human health. Traditional detection and quantification methods—including manual microscopy and standalone spectroscopic techniques—offer reliable accuracy but are limited by labor-intensive procedures and low
Background: Despite newer treatments with immunosuppressive agents, there still exists a considerable morbidity and mortality risk among patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Since 1994 the European Vasculitis Society (EUVAS) has aimed for an improved outcome for patients with AAV, conducting several prospective randomized controlled trials (RCTs).
Purpose of Review: Despite no general conclusions regarding the therapeutic effect of MSCs on virus-induced acute lung injury in pre-clinical studies, a significant number of clinical trials using MSC-based treatment for COVID-19-associated ARDS were initiated during the global pandemic. Here, we aimed to discuss differences and similarities in clinical trials using MSC-based treatments for classi
