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Glycerol-3-phosphate dehydrogenase is a biomedically important enzyme that plays a crucial role in lipid biosynthesis. It is activated by a ligand-gated conformational change that is necessary for the enzyme to reach a catalytically competent conformation capable of efficient transition-state stabilization. While the human form (hlGPDH) has been the subject of extensive structural and biochemical
Popular summary Estuarine eutrophication, the systemic limitation of oxygen in a body of water, has been increasingly monitored and scrutinized as an environmental concern needing acute and long term remediation efforts. The roots of eutrophication are largely attributed to anthropic sources within the watershed, sources that are products of modern civilization; such as agricultural and urban poll
This paper considers the effects of defects in the form of cracks on the failure properties in the thickness direction of multilayered board. The objective was to study how the peak stress value changes with various crack lengths under various load conditions. Specimens with manufactured cracks cut parallel to the machine-direction–cross-machine-direction plane were glued in the Arcan device and t
Kursutvärdering kursnamn Sida 1 av 2 Biologiska institutionen Grund- och avancerad utbildning KURSANALYS Datum 251209 Kursansvarig: Christoffer Johansson Antal studenter: 33 Antal svar: 8+2 Betyg: 4,0 Kursanalys: ”Ekologi”, ”BIOC10/12”, VT-24 Sammanfattning av kursvärderingen Studenterna har varit generellt nöjda med kursen (4,0), och med lärarnas insatser (3,8). Kommunikationen har fungerat ok (3
Untitled Sida 1 av 4 Biologiska institutionen Grund- och avancerad utbildning KURSANALYS Datum 2025-06-02 Kursansvarig: Allan Rasmusson Antal studenter: 24 (exkl. omreg.) Antal svar: 19 Omdöme: 3.8/5 Kursanalys: Molekylärbiologi, MOBA03, VT2025 Sammanställd av Allan Rasmusson i samråd med Urban Johanson Sammanfattning av kursvärderingen Mittkursvärdering: Enligt ombuden har kursens första del fung
Kursutvärdering kursnamn Centrum för miljö- och klimatvetenskap Grund- och avancerad utbildning KURSANALYS Datum 2025-05-22 Kursansvarig: Patrik Edén Antal studenter: 44 Antal svar: 10 Betyg (antal G, VG): 15G, 14VG Sida 1 av 2 Sida 2 av 2 Kursanalys: Introduktion till artificella neuronnätverk och djupinlärning (BERN04) höstterminen 2024 Sammanfattning av kursvärderingen Kursutvärdering saknade d
Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to deoxyribonucleotides, the building blocks for DNA synthesis, and are found in all but a few organisms. RNRs use radical chemistry to catalyze the reduction reaction. Despite RNR having evolved several mechanisms for generation of different kinds of essential radicals across a large evolutionary time frame, this initial r
Uncharacterized side activities of enzymes can have significant effects on reaction products and yields. Hence, their identification and characterization are crucial for the development of successful reaction systems. Here, we report the presence of feruloyl esterase activity in CtXyn5A from Acetivibrio thermocellus, besides its well-known arabinoxylanase activity, for the first time. Activity ana
Pyridoxal 5′-phosphate (PLP), the biologically active form of vitamin B6, is an essential cofactor in many biosynthetic pathways. The emergence of PLP-dependent enzymes as drug targets and biocatalysts, such as tryptophan synthase (TS), has underlined the demand to understand PLP-dependent catalysis and reaction specificity. The ability of neutron diffraction to resolve the positions of hydrogen a
Uncharacterized side activities of enzymes can have significant negative effects on reaction products and yields. Hence, their identification and characterization is crucial for the development of successful reaction systems. Here, we report the presence of feruloyl esterase activity in CtXyn5A from Acetivibrio thermocellus besides its well-known arabinoxylanase activity for the first time. Both r
In recent years, particularly following the definition of the UN Sustainable Development Goals (SDGs) for 2030, Nature-Based Solutions (NBS) have gained considerable attention, capturing the interest of both the scientific community and policymakers committed to addressing urban environmental issues. However, the need for studies to guide decision-makers in identifying suitable locations for NBS i
C4b-binding protein (C4BP) is a plasma glycoprotein involved in regulation of the complement system. C4BP consists of seven alpha-chains and one unique beta-chain, all constructed of repeating complement control protein (CCP) modules. The beta-chain, made up of three CCPs, binds tightly to vitamin K-dependent protein S, a cofactor to anticoagulant activated protein C. When bound to C4BP, protein S
We present a solution for long-term direct current resistivity and time-domain induced polarization (DCIP) monitoring, which consists of a monitoring system and the associated software that automates the data collection and processing. This paper describes the acquisition system that is used for remote data collection and then introduces the routines that have been developed for pre-processing of
The multi-layer dynamic model SAFE was applied to the forested catchment istebna (Southern Poland), to study recovery from acidification. Environmental pollution in the area has been historically high. The model uses data from an intensive monitoring plot established in 1999 in a spruce stand, which was planted in 1880. Observations showed that the soil was depleted of base cations. The measured b
Aim: It has been claimed that supraspinal structures are necessary forthe depression of nocifensive behaviour elicited by acupuncture or acupuncturelike (AL) stimulation. However, nocifensive reflexes in the spinal catwere inhibited for long periods by a mechanism releasing opieids on AL conditioning stimulation of groups II-III muscle afferents (Sj~lund and Eriksson, Neurosci.Lett. S3:264:1979).
