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Floods account for the majority of disasters caused by natural hazards worldwide, and their frequency and intensity are set to increase further as a result of climate change. To protect people and property, protective measures such as dykes and drainage systems are put in place. However, events that are often overlooked in this context are compound floods, in which several types of flooding occur
The Mediterranean subpopulation of sperm whales (Physeter macrocephalus) is classified as Endangered by the IUCN, yet the western Ionian Sea, a key corridor connecting the eastern and western Mediterranean sub-populations, remains a data-poor region for cetacean monitoring. Passive acoustic monitoring (PAM) offers an effective approach for long-term surveillance of this deep-diving species, but la
Spår i sanden: Mänsklig påverkan på sandstränder Att åka till stranden en varm sommardag är en populär aktivitet som många ser som en självklarhet. Inför badsäsongen rensas de populäraste stränderna på tång och annan stranddrift för att välkomna de snart kommande badgästerna och när tiden väl är inne fylls både stranden och dynlandskapet med folk som letar efter den perfekta platsen att slå sig nDuring the summer season, many popular beaches are subjected to human disturbances by way of excessive trampling and beach cleaning. Falsterbo beach in the south of Sweden is one example of this. By making plant establishment harder and removing important habitat structures, these types of disturbances have been shown to negatively influence the vegetation of coastal habitats, reducing both biodiv
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Inflammation plays an important role in different CVD such as atherosclerosis and myocarditis. Myocarditis is characterized by immune cell infiltration in the myocardium. This can lead to fibrosis, cardiac remodeling, progression to dilated cardiomyopathy and heart failure. New evidence highlights the role of immunometaboli
More than 70% of climate policies target low-carbon technologies, with hopes that policy support will trigger tipping points and self-reinforcing growth. In practice, however, trajectories of policy-driven technologies remain difficult to explain and anticipate because their growth is nonlinear and often constrained by backlash, policy reversals and systemic barriers. In this Perspective, we devel
Musculoskeletal health is essential to health, well-being, and independence across the life course. Musculoskeletal conditions including inflammatory joint diseases, osteoarthritis, back pain, osteoporosis, and fragility fractures are among the greatest causes of disability globally imposing a major burden on health and social care and economic impact also through lost productivity. Despite effect
Urban expansion is a defining feature of rapidly growing cities and has important implications for urban thermal behaviours, particularly in hot and semi-arid regions that are increasingly vulnerable to the effects of climate change. Tripoli, the capital of Libya, has experienced substantial urban growth over recent decades under conditions of weak planning and uneven development. Despite this, th
The structural organization of the gene for the human cysteine-proteinase inhibitor cystatin C was studied. Restriction-endonuclease digests of human genomic DNA hybridized with human cystatin C cDNA and genomic probes produced patterns consistent with a single cystatin C gene and, also, the presence of six closely related sequences in the human genome. A 30 kb restriction map covering the genomic
Some human papilloma viruses are thought to be associated with skin cancer. In this pilot study, 21 female renal transplant carriers, 10 with a history of skin squamous cell carcinoma and 11 without, together with 9 age-matched healthy women were investigated for human papilloma virus DNA in sun-exposed (forehead) and less sun-exposed (buttock) skin, mouth and uterine cervix. Paraffin-embedded tum
Human antibodies directed towards functionally associated tumor antigens have great potentials as adjuvant treatment in cancer therapy. Here we describe an efficient subtractive approach to select single chain Fv (scFv) antibodies, specifically binding to unknown rapidly internalizing tumor-associated antigens (TAA) on human breast and pancreatic carcinoma cell lines. After re-engineering the scFv
Laxity of the distal radioulnar (DRU) joint after distal radial fractures has a worse general outcome in patients before the usual age for development of osteoporosis. The hypothesis for this study was that patients with laxity also have less strength during supination and pronation. An apparatus for measuring strength in supination and pronation was constructed and validated. 20 patients were cho
