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We present the design, prototype developments and test results of the new time-of-flight detector (ToFD) which is part of the R3B experimental setup at GSI and FAIR, Darmstadt, Germany. The ToFD detector is able to detect heavy-ion residues of all charges at relativistic energies with a relative energy precision σΔE/ΔE of up to 1% and a time precision of up to 14 ps (sigma). Together with an el
Life cycle environmental problems have been addressed by a number of strategies, but with unsatisfactory results, since solutions are searched for within the same paradigms that give rise to the problems. This work questions the vision of linear material growth and searches for ways to sustain economic growth without putting the natural environment under stress. The research explores the concept o
Meta-analysis is a statistical method used in evidence synthesis for combining, analyzing and summarizing studies that have the same target endpoint and aims to derive a pooled quantitative estimate using fixed and random effects models or network models. Differences among included studies depend on variations in target populations (ie, heterogeneity) and variations in study quality due to study d
This article analyses the ideas and potential contribution of dematerialisation and eco-efficiency, and an innovation framework to promote Sustainability and increasing business competitiveness. From a strategic point of view and productivity approach, initiatives to reducing the resource intensity in producing products and providing services include: dematerialisation of the economy, extending pr
Environmental issues still have low priority within industries and universities in countries from the former Soviet Union. There is a weak link between academic R&D and industrial application, which leads to innovative retardation and economic backwardness. A short course conducted by IIIEE in Russia introduced Cleaner Production (CP) to both audiences and helped to gain some valuable insight
Code-switching is generally dispreferred at points of non-shared word order across a bilingual’s two languages. In priming studies, this dispreference persists even following exposure to a code-switched non-shared-word-order utterance. The present study delves deeper into the scope of code-switching priming by investigating whether lexical repetition across target and prime, a factor known to boos
This study was conducted as part of a government commission which wasgiven to the Swedish Environmental Protection Agency (Swedish EPA) in 2014.The Environmental Protection Agency mandated the International Institutefor Industrial Environmental Economics (IIIEE) at Lund University to conducta research study on nudging. The study has served and will serve as a directinput to further strategic work
Pointing with the chin is a practice attested worldwide: it is an effective and highly recognizable device for re-orienting the attention of the addressee. For the chin point to be observed, the addressee must attend carefully to the movements of the sender’s head. This demand comes into conflict with the politeness norms of many cultures, since these often require conversationalists to avoid meet
Since the colonial period spatial violence has been a regular occurrence for people throughout Yangon (Rangoon). These acts, led by successive state powers have only increased. Since 2021, the scale of these violences are unprecedented and country wide displaying raw brutality exerted by the junta.Yangon Stories is a collaborative research project aimed at documenting and bearing witness to the sp
Rapid-eye movement (REM) sleep behavior disorder (RBD), enactment of dreams during REM sleep, is an early clinical symptom of alpha-synucleinopathies and defines a more severe subtype. The genetic background of RBD and its underlying mechanisms are not well understood. Here, we perform a genome-wide association study of RBD, identifying five RBD risk loci near SNCA, GBA, TMEM175, INPP5F, and SCARB
Side-channel resilience is a crucial feature when assessing whether a postquantum cryptographic proposal is sufficiently mature to be deployed. In this paper, we propose a generic and efficient adaptive approach to improve the sample complexity (i.e., the required number of traces) of plaintext-checking (PC) oracle-based sidechannel attacks (SCAs), a major class of key recovery chosen-ciphertext S
Electroconvulsive therapy (ECT) is effective and safe for adults with severe depression, but less studied in adolescents. Here, we examined the indications, prevalence, practice, response and remission rates, and side effects in young people treated with ECT in Sweden. We also examined the usage of ECT in the transition to adult psychiatry. Using data from national patient registers and the Swedis
Background: The nature of free, uncomplexed prostate-specific antigen (s) in the circulation is still unknown. In this study, we developed novel anti-PSA antibodies using PSA produced by a metastasized cancer cell line, LNCaP, as an immunogen. Methods: Hybridoma cell lines were screened with different methods that aimed at finding antibodies specific for the forms of free PSA produced by LNCaP cel
Purpose: Prostate specific antigen (PSA) exists in the serum in several molecular forms that can be measured by immunodetectable assays: free PSA, PSA complexed to alpha 1-antichymotrypsin (complexed PSA) and total PSA, which represents the sum of the free and complexed forms. We determined the normal distribution of values and established the appropriate reference ranges for these 3 molecular for
Background: The favorable properties of lanthanide chelates compared with conventional fluorescent probes have attracted considerable interest. A Eu3+ chelator, 4,7-bis(chlorosulfophenyl)-1,10-phenanthroline-2,9-dicarboxylic acid (BCPDA), has been synthesized previously. Methods: We here describe immunoassay, immunohistochemistry, and microarray applications of a new streptavidin-based universal p
We describe a novel assay for detection of point mutations. The method combines the specificity and sensitivity of the polymerase chain reaction (PCR) and allele-specific oligonucleotides (ASO) with highly sensitive time- resolved fluorometry. ASO probes differing by a single base substitution and labeled with europium (Eu) chelates were hybridized in solution simultaneously with a biotinylated ol
Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal antibody against β‐MSP were used for immunocytochemical detection of the respective antigens in different organs from different species. SG immunoreactiv
Background: The free PSA fraction in serum of patients with various prostatic disorders is essentially unreactive with the anti-proteases in blood. Recently reported data show that it is likely to consist of a mixture of proPSA, internally cleaved PSA forms, and possibly other uncharacterized forms. Currently there are no specific methods available to measure the different free PSA subfractions an
